Gene Details:

• Gene ID: MDP0000323311
• Gene Symbol: MdFRK2
• Gene Name: fructokinase 2
• Genome: Golden ASM211411v1
• Species: Malus domestica

Functional Descriptions:

• Increased activity of MdFRK2, a high-affinity fructokinase, leads to upregulation of sorbitol metabolism and downregulation of sucrose metabolism in apple leaves.
• MdFRK2 ectopic expression was associated with a general decrease in fructose concentration in transgenic lines.
• In the fruit of transgenic apple with decreased sorbitol synthesis, MdFRK2 was suggested as a main regulating factor of fructose homeostasis.
• The results demonstrate that overexpression of MdFRK2 in apple alters the allocation of photosynthetic carbon flux from sucrose to sorbitol, thereby changing sugar concentrations and homeostasis in apple leaves.

Function-related keywords:

• homeostasis ,  sugar ,  sucrose ,  sugar-homeostasis ,  fructose

Literature:

• Increased activity of MdFRK2, a high-affinity fructokinase, leads to upregulation of sorbitol metabolism and downregulation of sucrose metabolism in apple leaves.   DOI:  10.1038/s41438-018-0099-x ;  PMID:  30534388

Related News:

Gene Resources:

• NCBI ID:
• UniProt accessions:

Orthologs:

Sequences: