Gene Details:

• Gene ID: MDP0000319941
• Gene Symbol: MdTCP46
• Gene Name: Teosinte branched1/cycloidea/proliferating transcription factor 46
• Genome: Golden ASM211411v1
• Species: Malus domestica

Functional Descriptions:

• The expression of MdTCP46 was responsive to high light intensity, and under these conditions it promoted anthocyanin biosynthesis by direct interactions with MdMYB1 that enhanced the binding of the latter to its target genes.
• MdTCP46 also interacted with a bric-a-brac/tramtrack/broad (BTB) protein, MdBT2, that is responsive to high light intensity, which ubiquitinated MdTCP46 and mediated its degradation via the 26S proteasome pathway.
• MdBT2 suppressed the role of MdTCP46 by inducing its ubiquitination, resulting in subsequent degradation via the 26S proteasome pathway.
• Our results demonstrate that the dynamic regulatory module MdBT2-MdTCP46-MdMYB1 plays a key role in modulating anthocyanin biosynthesis at different light intensities in apple, and provides new insights into the post-transcriptional regulation of TCP proteins.

Function-related keywords:

• anthocyanin-biosynthesis ,  anthocyanin ,  protein

Literature:

• Dynamic regulation of anthocyanin biosynthesis at different light intensities by the BT2-TCP46-MYB1 module in apple.   DOI:  10.1093/jxb/eraa056 ;  PMID:  31996900

Related News:

Gene Resources:

• NCBI ID:
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