Gene Details:

• Gene ID: MDP0000245133
• Gene Symbol: MdCOP1
• Gene Name: CONSTITUTIVELY PHOTOMORPHOGENIC 1
• Genome: Golden ASM211411v1
• Species: Malus domestica

Functional Descriptions:

• The apple BTB protein MdBT2 positively regulates MdCOP1 abundance to repress anthocyanin biosynthesis.
• The ubiquitin ligase CONSTITUTIVELY PHOTOMORPHOGENIC 1 (MdCOP1) plays a central role in light-induced anthocyanin biosynthesis.
• Enhances MdCOP1-mediated ubiquitination and 26S proteasome-mediated degradation of MdMYB1, thereby reducing transcription of anthocyanin biosynthesis genes and inhibiting anthocyanin accumulation and fruit coloration in apple
• Our findings reveal a molecular mechanism by which MdBT2 positively regulates MdCOP1, providing insight into MdCOP1-mediated anthocyanin biosynthesis.

Function-related keywords:

• ubiquitin ,  anthocyanin-biosynthesis ,  anthocyanin ,  protein

Literature:

• The apple BTB protein MdBT2 positively regulates MdCOP1 abundance to repress anthocyanin biosynthesis.   DOI:  10.1093/plphys/kiac279 ;  PMID:  35674376
• The apple MdCOP1-interacting protein 1 negatively regulates hypocotyl elongation and anthocyanin biosynthesis.   DOI:  10.1186/s12870-020-02789-3 ;  PMID:  33407118

Related News:

Gene Resources:

• NCBI ID:
• UniProt accessions:

Orthologs:

Sequences: