Gene Details:

• Gene ID: MDP0000237742
• Gene Symbol: MdMAPK3
• Gene Name: MITOGEN-ACTIVATED PROTEIN KINASE 3
• Genome: Golden ASM211411v1
• Species: Malus domestica

Functional Descriptions:

• Ethylene enhances MdMAPK3-mediated phosphorylation of MdNAC72 to promote apple fruit softening.
• Identified apple MITOGEN-ACTIVATED PROTEIN KINASE 3 (MdMAPK3) as an important positive regulator of ethylene-induced apple fruit softening during storage.
• MdMAPK3 interacts with and phosphorylates the transcription factor NAM-ATAF1/2-CUC2 72 (MdNAC72), which functions as a transcriptional repressor of the cell wall degradation-related gene POLYGALACTURONASE1 (MdPG1).
• The increase in MdMAPK3 kinase activity was induced by ethylene, which promoted the phosphorylation of MdNAC72 by MdMAPK3. Additionally, MdPUB24 functions as an E3 ubiquitin ligase to ubiquitinate MdNAC72, resulting in its degradation via the 26S proteasome pathway, which was enhanced by ethylene-induced phosphorylation of MdNAC72 by MdMAPK3.
• This study thus reveals that the ethylene–MdMAPK3–MdNAC72–MdPUB24 module is involved in ethylene-induced apple fruit softening, providing insights into climacteric fruit softening.

Function-related keywords:

• transcription-factor ,  kinase ,  ethylene ,  cell-wall ,  protein-kinase ,  transcriptional-regulator ,  transcription-regulator ,  ubiquitin ,  ubiquitin-e3-ligase ,  transcriptional-repressor ,  protein

Literature:

• Ethylene enhances MdMAPK3-mediated phosphorylation of MdNAC72 to promote apple fruit softening.   DOI:  10.1093/plcell/koad122 ;  PMID:  37132483

Related News:

Gene Resources:

• NCBI ID:
• UniProt accessions:

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