Gene Details:
- Gene ID: MDP0000230486
- Gene Symbol: MdCIP1
- Gene Name: COP1-interacting protein 1
- Genome: Golden ASM211411v1
- Species: Malus domestica
Functional Descriptions:
- Expression pattern analysis showed that MdCIP1 was constitutively expressed in various tissues of apple, and responded to stress and hormone signals at the transcriptional level.
- Ectopic expression of MdCIP1 complemented the phenotypes of the Arabidopsis cip1 mutant, and MdCIP1 inhibited anthocyanin biosynthesis in apple calli.
- MdCIP1 interacts with MdCOP1 and inhibits apple anthocyanin biosynthesis in an MdCOP1-mediated pathway.
- It is presumed that the MdCIP1-MdCOP1-MdMYB1 pathway may also be used to reveal the regulation mechanism of anthocyanin biosynthesis by hormonal and environmental signals, providing a new perspective on the hormonal and environmental impact on fruit coloration.
Function-related keywords:
Literature:
- The apple MdCOP1-interacting protein 1 negatively regulates hypocotyl elongation and anthocyanin biosynthesis. DOI: 10.1186/s12870-020-02789-3 ; PMID: 33407118
Related News:
Gene Resources:
Orthologs:
Sequences:
cDNA Sequence
CDS Sequence
- >MDP0000230486
ATGCCAAAGCACCGCATGAGGGAAATTAAGTCCTTATTTGGAAGTCACATCAATTCACAGAAGCATGAAGAGCTGAAAGGAACTAAAATAGGTATTGAGGAGAAGGTGAATAAAATATTGAAGCTTCTAAAAAATGAAGAGCTTAAAAAAGATGACATCCCAGTAGAGAACTCCAAAGTGGAACCTCTCGCTGAGCTAATTCAGGATTTCCACAAGGATTACCAATCACTGTATGCACAATATGATCAACTAACTGGAGCGCTGAAGGAAAAAGTTTGGAGCAAACAAGAAAAGGACAACAGCTCTTCATCAAGTTCAGACTCAGATTCCGATCATTCTTCAAATGAAAAAAGCCGTAAAAATGGAGTGATGGAAAGTGACTTTCAGAAAATAACTGATGGGATCAAGCAGGAACTTGAATTGGCACATCAAGAAGTTGCTGACCTGAAGAGGAGATTGACCGCTACAAGTGAAGAGAAGGAAGCTTTAAGCTCAGATTGTGCGGCGGCTTTGACCAAGATAGAAGAAAAGGAGAGTGTTTTTATTGACTTGAAGACTGCAGCTGAAAGGTTAGATGCTGAAAAATCACTACTTTTGGCTGAGAATGGTGAGCTAAAACAAAAACTGGAAGCTGGTGGAAAGATAGAAGCTGAATTGATTCAAAAAGTGGAAGATGTGGAAGGAGAGAAAGATAACTTGATTAAGGAGAAAGAGACTGCTCTGAGAACGATTGAAGATGGAGAGACTATTACAGCGGAATTAAGAACCGTGATTGATCGGCTGAAAGATGAAAAAGTAACCCTTGAGCAAGAACTAGAATCTGTTCGAGGGGAAGTCATCCATATAAAGCAGAAGCTGCAATCTGCAGAAGAGCAGGTATCAGATTTAAGCCACAATCTGAAAGCCAAGGAGGAAGAAACAACTGAATCTAGTCAGCTACGGGAGAAATTGGGTCAGAGGGAAGTGGAATATTTGGCTCTGTCTGAGATGCATGAGCTGCATGAGAAGGAAACTTTGGCTCAAATTATGGAATTACAGGCTGCTGTGACAGGGCTGGAACTGGAGCTGGAATCTTTGCGAGCTCAGAAAAGAGATATGGAAGTGAAGATTGAGAGCACAGAAGCTGAAGTAAAACAACTGGGAGAGGTGAGTGCAGGACTGCAAGTCCAAATTTCAGAAGTTGAGTCAATATCAAATGAGAAAGCAGCAGAACTTTCTGCTCTCACGAAAAACCTTGAAGATTACAAAAGTGAATCTATTCAGCTGAAGGAGAAATTGGGTCAGAGGGAAGTGGAATGCTCAGCTCTGTCTGAGATGCATGAGCTGCATAAGAGTAAAACATTGGCTCAAATTACGGGATTAGAGGCTGCTGTGGCAGGGCTGGAACTGGAGCTGGAATCTTTGCGAGGTCAGAAAACAGATATAGAAGTTGAGATTGAGAACAAAGAAACTCAAGTGAAACAACTAGCAGAAGAGAACGCGGGACTGCAAGCCCGAATTTCACAACTTGAATCAATATCAAATGAGAGAGAAGCCGAATTTTCTTCCCTGGCAAAGAAATTTGAGGACAGCAGTAATGAATATGGTCAGCTACAGGAGAAACTGGGTCAGAGGGAAGTGGAACACTCAACTCTGTCTGAGATGCATGAGCTGCATAAGAGTAAAACATTGGCTCAAATTACAGGTTTAGAGGCTGCTGTGGCAGGGCTGGAACTGGAGCTGGAATCTTTGCGAGATCAGAAAAAAGATATAGAAGTTGAGATTGAGAAGAAAGAAACTCAAGTGAAACAACTAGCCGAAGAGAATGCGGGATTGCAAGCCCAAACTTCAGAACTTGAATCAATATCAAATGAGAGAGAAGCTGAACKTTCTGCTCTCACCAMAAAACTTGRGGAGATCAATRGTGAATCTATTCAGCWGAAGGAGCAATTGGATCAGAAGGAAAAGGAATACTCAGCTCTGTCTGAGAAGCATGAGCTGCATGAGAGTAAAACATCGGCTCAAATCCTGGGATTAGAGGCTGCTGTGGCAGGGCTGGAACTGGAGCTRAGATCTTTGCGAGGTCAGAAAGAAGATATAGATGTTGAGATTGAGAACAAAGAAACTCAAGTMAAACAACTAGCAGAAGAGAATGTGGGACTGCAAGCCCGAATTTCACAACTTGAATCAATATCAAATGAGAGAGAAGCCGAATTTTCTTCCCTGGMGAAGAAATTTGAGGACAGCAGTAATGAATATGGTCGGCTRCAGGAAAAACTGGGTCAGAGGGAAGTGGAACACTCAACTCTGTCTGAGATGCATGAGCTGCATAARAGTAAAACTTTGGCTCAAATTACAGGTTTAGAGGCTGCTGTGGCAGGGCTGGAACTGGAGCTGGAATCTTTGMGAGRTCAGAAAAAAGATATAGAAGTTGAGATTGAGAAGAAAGAAACTCAAGTGAAACAACTAGCMGAAGAKAATGCGGGATTGCAAGCCCAAACTTCAGAACTTGTATCAATATCAAATGAGAGAGAAGCTGAACKTTCTGCTCTCACCAMAAAACTTGAGGAGATCAATAGTGAATCTATTCAGCTGAAGGAGMAATTGGATATMGAWGTTGAGATTGAGAACAAAGAAACTCAAGTRAAACAACTAGCAGAAGAGAATGYGGGACTGCAAGCCCGAATTTCACAACTTGAATCAATATCAAATGAGAGAGAAGCCGAATTTTCTTCCCTGGCRAAGAAATTTGAGGACAGCAGTAATGAATATGGTCRGCTRCAGGAAAAACTGGGTCAGAKGGAAGTGGAACACTCAACTCTGKCTGAGATGCATGAGCTGCATAAGAGTAAAACKTTGGCTCAAATTACAGGTTTAGAGGCTGCTGTGGCAGGGCTGGAACTGGAGCTGGAATCYTTGMGAGRTCAGAAARAAGATATAGARGTTGAGATTGAGAAGAAAGAAACTCAAGTGAAACAACTAGCMGAAGAKAATGYGGGATTGCAAGCCCRAAYTTCAGAACTTGWATCAATATCAAATGAGAGAGAAGCTGAACTTTCTGCTCTSACSAARAAACTTGAGGASAKCARTARTGAATGGCTAGMACTGGAGCTGGAATCTTTGCGACATGAGAARAGWGRTWTSGAAGTAGAGATCGAGARCAAAGAAACTGTAGCAAAACAACTGGGAGAGGAAAATGCGGGACTGCAAGCCCGAATTTCAGAACTTGAATCGACTTTGAAAGACAGAGAAGCTGAACTTTCCGATCTCACGAAGAAACTTGAGGACAGCAATCATGAATCGTCATCCAGAATAGCAGATTTGTCCGCACAGATCAATAATCTGCTAGCTGAGGTAGATTCTTTGCGTGCCCAGAAAGTTGAGTTGGAGGAACTTATAGTATCCAAAGGTGATGAAGCATCGACTCAGGTCAAGGGATTAACGGAACAAGTAAATGTGTTGCAGCAGGAATTGTTGTCAATGCAGAGCGGGAAAACTGAATTGCAAGTGCAGCTTGAGAACAAAACTCAAGAAATAACGGATCATGAGAGGGTTGTGGAAGAGAAAGAGAGTTTGACGGCAGAAAAGAGAGAGATTGAGATAAAGGTGGACTCAATACACAACCACAAAAGTGAACTCGAAGAGGAGATAAGAACAAAATGCCTCGAGAGTGATCAATTGAGAGTGGAAATTGTTGAGCTAAGGGATCAAATTGTTGAATTTGAGAGGAGACTAACAGAAAAAGAGGCCGAGTTTTCTTCCCTCCAGGAGAAACATGACAGTGCAGTGAATGACACTTCTGCTCAAATAACAGCCTTTGTATCACAGGTTACTAATCTACAACAGGATTTGGATTCATTGCAGGCTGAGAAGAACCAGATGGAGTTGCAGTTTGAGAGGGAGAAACAAGAACTTTCACAGAGCCTGACGCAATTGGAAAATGAAAAGGTTGAGTTAGAGAGCAAGATTGCTGATCATCAGAGACTGCTGAATGAACACGAGGAGACATATGGCAAGTTAAAAGATGAATATATGCAGCTGGAGAGTCATATCCAGGACAGTAAGGTCAACCAAGACGCTGCAGAAAGGAAAATCGAGCAAATGGCGGAAGATTTCAGTAAGAAAATTGAATCCAAAGATGAGACAATAGCTGATTTGGAGCAAGAGGCTGAATATCTGAAACGAGATCTTGAAGAAAAAGGGTACGAGCTTAGTTCTTTGGTTGAAAACTCCCGTAATGTTGAAGTTAAGCTCCGCCTGTCAAACCAGAAGCTCCGGGTTACAGAGCAGGTATTGACTGAGAAAGAGGAGAGCTTCAGAAAGGCAGAACTGAAATTCCTGGAAGAACAGAGAGCACTTGAAGACAGGATTGCTAGATTGTCTGATATAATCTCTGCAAACAACGAAGCCTATCAAAGAAACATCACACTTGTTGCAGAAAATGTGAACAGTTATTTCAGCGGAATGGAATCCATGATAAAAAAATTTATGGACGACTGTGCAGAGTATGAGACGTGCATTCTGGAAACATCGCAGGAGCTTCACGTTGCAAAGAATTGGGTTGCAGAAACAAGGAGTGAAAGAGAGACGTTGAAGAGGGAGGTGGGGGACCTAATTGAACAACTGCGAGATAAGAAAGAAGAAGCATTGGTGCTTGGAGAGCAGGTCGAGAGGATGCGGGCAAAGGCAAGCAAGGAAGAAGTGGAGAAGGGGAGTCTGATCAAGGCCATGAGCCAACTTGAGAAGAAAGCGGCGGACTTGGAGAAGGTGGTGGAGGAGAAAACAGAGGGAATGCTGGGATTAGGAGAGGAGAAGAGGGAAGCCATAAGACAGTTGTGCATATGGATCGAGTATCACCAAAGCCGGTACGATCATCTCAAGGAAATTCTCTCGAAGACAACTCCTGCAAGAGGCCAGACGAGGGCTTCGACATCTCGTCCTTGA
Protein Sequence
- >MDP0000230486
MPKHRMREIKSLFGSHINSQKHEELKGTKIGIEEKVNKILKLLKNEELKKDDIPVENSKVEPLAELIQDFHKDYQSLYAQYDQLTGALKEKVWSKQEKDNSSSSSSDSDSDHSSNEKSRKNGVMESDFQKITDGIKQELELAHQEVADLKRRLTATSEEKEALSSDCAAALTKIEEKESVFIDLKTAAERLDAEKSLLLAENGELKQKLEAGGKIEAELIQKVEDVEGEKDNLIKEKETALRTIEDGETITAELRTVIDRLKDEKVTLEQELESVRGEVIHIKQKLQSAEEQVSDLSHNLKAKEEETTESSQLREKLGQREVEYLALSEMHELHEKETLAQIMELQAAVTGLELELESLRAQKRDMEVKIESTEAEVKQLGEVSAGLQVQISEVESISNEKAAELSALTKNLEDYKSESIQLKEKLGQREVECSALSEMHELHKSKTLAQITGLEAAVAGLELELESLRGQKTDIEVEIENKETQVKQLAEENAGLQARISQLESISNEREAEFSSLAKKFEDSSNEYGQLQEKLGQREVEHSTLSEMHELHKSKTLAQITGLEAAVAGLELELESLRDQKKDIEVEIEKKETQVKQLAEENAGLQAQTSELESISNEREAEXSALTXKLXEINXESIQXKEQLDQKEKEYSALSEKHELHESKTSAQILGLEAAVAGLELELRSLRGQKEDIDVEIENKETQVKQLAEENVGLQARISQLESISNEREAEFSSLXKKFEDSSNEYGRLQEKLGQREVEHSTLSEMHELHKSKTLAQITGLEAAVAGLELELESLXXQKKDIEVEIEKKETQVKQLAEXNAGLQAQTSELVSISNEREAEXSALTXKLEEINSESIQLKEXLDIXVEIENKETQVKQLAEENXGLQARISQLESISNEREAEFSSLAKKFEDSSNEYGXLQEKLGQXEVEHSTLXEMHELHKSKTLAQITGLEAAVAGLELELESLXXQKXDIEVEIEKKETQVKQLAEXNXGLQAXXSELXSISNEREAELSALTKKLEXXXXEWLXLELESLRHEKXXXEVEIEXKETVAKQLGEENAGLQARISELESTLKDREAELSDLTKKLEDSNHESSSRIADLSAQINNLLAEVDSLRAQKVELEELIVSKGDEASTQVKGLTEQVNVLQQELLSMQSGKTELQVQLENKTQEITDHERVVEEKESLTAEKREIEIKVDSIHNHKSELEEEIRTKCLESDQLRVEIVELRDQIVEFERRLTEKEAEFSSLQEKHDSAVNDTSAQITAFVSQVTNLQQDLDSLQAEKNQMELQFEREKQELSQSLTQLENEKVELESKIADHQRLLNEHEETYGKLKDEYMQLESHIQDSKVNQDAAERKIEQMAEDFSKKIESKDETIADLEQEAEYLKRDLEEKGYELSSLVENSRNVEVKLRLSNQKLRVTEQVLTEKEESFRKAELKFLEEQRALEDRIARLSDIISANNEAYQRNITLVAENVNSYFSGMESMIKKFMDDCAEYETCILETSQELHVAKNWVAETRSERETLKREVGDLIEQLRDKKEEALVLGEQVERMRAKASKEEVEKGSLIKAMSQLEKKAADLEKVVEEKTEGMLGLGEEKREAIRQLCIWIEYHQSRYDHLKEILSKTTPARGQTRASTSRP