Gene Details:
- Gene ID: MDP0000029168
- Gene Symbol: MdMYC2
- Gene Name: Jasmonate-Activated Transcription Factor 2
- Genome: Golden ASM211411v1
- Species: Malus domestica
Functional Descriptions:
- MdMYC2 is a homology of Arabidopsis MYC2 in apple, it has highly similarity in structure and function to the Arabidopsis MYC2.
- MdMYC2 is involved in anthocyanin biosynthesis and in a hypersensitization response to MeJA.
- MdERF1B–MdMYC2 module integrates ethylene and jasmonic acid to regulate the biosynthesis of anthocyanin in apple.
- When the JA concentration increases, JAZ proteins are degraded via the ubiquitination pathway, which results in the release of MdERF1B, which then activates MdMYC2 and MdMYB1/9/11 expression. The encoded TFs subsequently induce the expression of the downstream genes associated with anthocyanin synthesis, leading to anthocyanin production.
- Transcription factors MdMYC2 and MdMYB85 interact with ester aroma synthesis gene MdAAT1 in apple.
- The expression of MdMYC2, encoding a transcription factor involved in the JA signaling pathway, was enhanced by MeJA treatment in apple fruits, and MdMYC2 directly bound to the promoters of both MdACS1 and the ACC oxidase gene MdACO1 and enhanced their transcription.
- The Jasmonate-Activated Transcription Factor MdMYC2 Regulates ETHYLENE RESPONSE FACTOR and Ethylene Biosynthetic Genes to Promote Ethylene Biosynthesis during Apple Fruit Ripening.
Function-related keywords:
- transcription-factor , jasmonate , ja , ethylene , jasmonic , jasmonic-acid , signaling-pathway-gene , jasmonate-response , ja-biosynthesis , ethylene-response , ethylene-production , ja-signaling , anthocyanin-biosynthesis , anthocyanin
Literature:
- The molecular cloning and functional characterization of MdMYC2, a bHLH transcription factor in apple. DOI: 10.1016/j.plaphy.2016.06.032 ; PMID: 27404131
- MdERF1B-MdMYC2 module integrates ethylene and jasmonic acid to regulate the biosynthesis of anthocyanin in apple. DOI: 10.1093/hr/uhac142 ; PMID: 36072842
- Transcription factors MdMYC2 and MdMYB85 interact with ester aroma synthesis gene MdAAT1 in apple. DOI: 10.1093/plphys/kiad459 ; PMID: 37590971
- The Jasmonate-Activated Transcription Factor MdMYC2 Regulates ETHYLENE RESPONSE FACTOR and Ethylene Biosynthetic Genes to Promote Ethylene Biosynthesis during Apple Fruit Ripening. DOI: 10.1105/tpc.17.00349 ; PMID: 28550149
Related News:
Gene Resources:
- NCBI ID: NM_001328944.1
- UniProt accessions:
Orthologs:
Sequences:
cDNA Sequence
CDS Sequence
- >MDP0000029168
ATGACGGACTACCGGATACCGCCGACGATGAATCTATGGACGGACGACAACGCGTCCTTAATGGAGGCGTTTATGAGCTCATCCGATATGGCGTCGTTTTGGGCGGCGCCGCCGGCCCAGCCCACACCTCAACCCGCTCACGCTCCGCCCCAGCCGCAATCCTCGGCGTCCACCTCAGACTACCCCAAGGCCCCTGTTGCCGCCCAATTCCAGCCGTCCGCCACGCCCTTCAACCAGGAAACCCTCATGCAGCGCCTACAGGCCCTGATCGAAGGCGCGCGTGAGAGCTGGACCTACGCCATCTTCTGGCAGTCTTCCTACGACTACTCCGGCGCCGGCGCCGTTCTTGGATGGGGCGAAGGATTTTATAAAGACGAGCGGGACAAGGTTAAGGCCAAGGCGAAAACGACGACGTCCGCCGCCGAACAAGAGTACCGCAAGAAAGTCCTCCGAGACCTGAATTCCTTGATTTCCGGCGCCGACACGTCAGCAGACGACGCCGTCGTTGATCAGGAAGTGACTGATACTGAGTGGTTCTTTCTGGTGTCCATGACTCAGTCGTTCGTCAACGGCGGCGGGCTCCCGGGTCAGGCCTTCTTTCACTCCACCCCGGTCTGGGTTGCTGGACCGGACCGGCTGGCGGCCTCGGCGTGCGAGAGGGCGCGTCAGGGTCACGTGTTTGGGCTGCAGACTATGGTTTGCGTTCCGACGGCGAATGGGGTTGTGGAGTTGGGCTCGACCGAGCTCATCTACCAGACCTCCGATCTGATGAACAAGGTCAGGGTTTTGTTCAATTTCAACAATTTGGAGGTCGGTTCTTGGCCTATGGCAGGCGCCGCCGCCGCCGCCACCGCCGATCAGGGCGAGAACGACCCTTCGCTCTGGCTCAACGACCCGTCGACCACCACCATGGAAGTGAAGGACCCGGTGAATGCTTCGGCACCCACCAGCACCAGCAACCAGCCCATTTCAAAGCCGATTCAGTTCGACAACCACCCGAGCTCCAGTAGCTTATCCGAGAACCCAAGCCCGGTTCAAGTACCACAATTACAGCAGCAAGTACAACAACAACAGCAAACGCAGAGCTTCTTCACCAGGGAGCTCAATTTCTCCGACTACAACGGATATGACAGGAGCAGCGTGAAGAATTCGAMTTCCAATTCGCATTCGTTGAAGCCCGAATCGGGCGAGATTTTGAATTTYGGGGAGAGCAAGAGGAGCTCTTACAGCGCCAACGGGAAATTGTTCTCGGGGCATTCCCAAATCGCCGCCGCTGAGGATAACAACAGCAAAAAGAAGAGGTCCCCGCCGTCGCTGGGTAGCAACGAGGAGGGGATATTGTCCTTTAGTTCGGGAGTGATTTTGCCGTCCAGCGGTGTGGGGAAATCCAGCGGCGTTGCCGATTCAGACCACTCGGACCTCGAAGCGTCGGTGGTTAGGGAGGCGGATAGTAGCCGAGTTGTTGACCCGGAAAAACGACCCAGAAAACGGGGACGGAAACCGGCGAATGGGAGAGAAGAGCCACTGAATCACGTGGAAGCAGAGCGGCAAAGAAGAGAGAAGCTTAACCAGAGATTCTACGCGCTCCGAGCAGTAGTCCCAAACGTATCGAAAATGGACAAAGCGTCGCTGCTYGGAGACGCCATATCCTACATCAACGAGCTCAAGKTGAAGCTGCAGACGGTAGAGACGGATAAAGAGGAGTTGCAGAAGCAATTGGAGTCGATGAACAAGGACTTGCCCAGCAAAGATTCGAGGTCGTCGGGTTCGACCGTGTYAGAGCACGAAATGAAAGGGTCTAGCAGTAAATTGTTAGACATGGACATTGACGTGAAGATAATCGGAAGGGACGCCATGATTCGAATTCAGTGTTGCAAGAAGAACCACCCGGCCGCGAGGCTAATGGCGGCTCTCAAGGAGCTCGACTTGGAAGTACACCACGCCAGCGTTTCTGTAGTCAACGATTTGATGATCCAACAAGCCACCGTGAAAGCGGGTAGCCGGATTTACACGCAGGATCAGCTCCGGTTAGCTCTACATTCCAAAGTTGGCGATGCCCGC
Protein Sequence
- >MDP0000029168
MTDYRIPPTMNLWTDDNASLMEAFMSSSDMASFWAAPPAQPTPQPAHAPPQPQSSASTSDYPKAPVAAQFQPSATPFNQETLMQRLQALIEGARESWTYAIFWQSSYDYSGAGAVLGWGEGFYKDERDKVKAKAKTTTSAAEQEYRKKVLRDLNSLISGADTSADDAVVDQEVTDTEWFFLVSMTQSFVNGGGLPGQAFFHSTPVWVAGPDRLAASACERARQGHVFGLQTMVCVPTANGVVELGSTELIYQTSDLMNKVRVLFNFNNLEVGSWPMAGAAAAATADQGENDPSLWLNDPSTTTMEVKDPVNASAPTSTSNQPISKPIQFDNHPSSSSLSENPSPVQVPQLQQQVQQQQQTQSFFTRELNFSDYNGYDRSSVKNSXSNSHSLKPESGEILNFGESKRSSYSANGKLFSGHSQIAAAEDNNSKKKRSPPSLGSNEEGILSFSSGVILPSSGVGKSSGVADSDHSDLEASVVREADSSRVVDPEKRPRKRGRKPANGREEPLNHVEAERQRREKLNQRFYALRAVVPNVSKMDKASLLGDAISYINELKXKLQTVETDKEELQKQLESMNKDLPSKDSRSSGSTVXEHEMKGSSSKLLDMDIDVKIIGRDAMIRIQCCKKNHPAARLMAALKELDLEVHHASVSVVNDLMIQQATVKAGSRIYTQDQLRLALHSKVGDAR