Gene Details:

  • Gene ID: MDP0000207103
  • Gene Symbol: MdMIPS2
  • Gene Name: Malus domestica the rate-limiting gene of myo-inositol biosynthesis 2
  • Genome: Golden ASM211411v1
  • Species: Malus domestica

Functional Descriptions:

  • Decreasing myo-inositol biosynthesis in apple lines by RNA silencing of MdMIPS1/MdMIPS2 led to extensive programmed cell death, which manifested as necrosis of both the leaves and roots and, ultimately, plant death.
  • MI complementation (or depletion) assays verified that the decreased MI production directly caused necrosis in MdMIPS1/MdMIPS2-silenced lines.
  • Our results revealed normal meristems and leaf primordium when necrosis was apparent in MdMIPS1/MdMIPS2-silenced lines, demonstrating that decreased MI biosynthesis did not disrupt apple organogenesis; instead, it greatly perturbed plant growth.

Literature:

Gene Resources:

  • NCBI ID:
  • UniProt accessions:

Sequences:

cDNA Sequence
CDS Sequence
  • >MDP0000207103
    ATGTTCATCGATAGCTTTAAGGTAGASTCCCCGAACGTGGTGTACACAGAGAATGAGATTCATTCGGTGTACAGCTACGAAACCACTGAGCTTGTGCATGAGAACAGAAATGGAAAGTATCAGTGGATTGTGAAGCCCAAATCTATCAAATACGAATTCAAGACTGATATCCATGTCCCCAAACTAGGGGTAATGCTGGTGGGTTGGGGTGGAAACAATGGCTCAACCCTCACTGCTGGTGTGATTGCAAACAGAGAAGGAATCTCCTGGGCAACCAAAGACAWGGTGCAACAAGCCAACTACTTTGGCTCACTGACCCAAGCCTCATCCATCCGTGTTGGGTCTTTCAACGGCGAGGAGATTTATGCCCCGTTCAAGAGCCTCCTGCCTATGGTGAAGCCCGATGACATTGTGTTTGGGGGTTGGGACATTAGTGACATGAACTTAGCAGATGCAATGGCAAGGGCAAAGGTCCTTGACATTGATCTGCAAAAGCAACTGAGGCCATACATGGAGTCCATGCTCCCACTCCCTGGAATCTACGACCCCGATTTCATCGCTGCCAACCAAGGTGCTCGTGCCAACAACGTCATCAAGGGCACCAAGAAGGAACAACTCCAACAAGTCATTAAAGACATTAGGGAGTTCAAGGAGAAGAGCAAGGTGGACAAGGTGGTTGTGCTGTGGACTGCCAACACTGAAAGGTATAGTAATGTGATTGTGGGGCTAAACGACACCGTTGAGAACCTGTTGGGTTCGGTGGACAAGAATGACGCTGAGATATCTCCTTCCACATTGTATGCCATAGCTTGTGTTCTTGAAAATGTTCCTTTCATCAATGGAAGCCCACAAAACACTTTTGTCCCAGGACTCATTGATTTGGCAATTAGGAGAAACAGTTTGATCGGTGGAGATGACTTTAAGAGTGGTCAGACCAAGATGAAGTCTGTGTTGGTTGATTTCCTTGTTGGGGCTGGAATCAAGCCAACATCCATAGTGAGCTACAACCATCTTGGGAACAATGACGGCATGAACCTTTCCGCACCGCAAACCTTCCGGTCAAAAGAGATTTCAAAGAGCAATGTTGTGGATGACATGGTGTCCAGCAATGGCATCCTCTACGGGCCAGGCGAGCACCCTGACCATGTTGTGGTGATCAAGTATGTGCCATATGTTGGGGACAGCAAGAGAGCCCTGGATGAGTACACCTCTGAGATTTTCATGGGTGGGAAAAGCACCATTGTGTTGCACAACACCTGTGAGGATTCCCTCTTGGCTGCTCCTATCATCCTCGATTTAGTTCTCCTCGCTGAACTCAGCACCCGTATCCAGCTCAAATCTGAAGCAGAGGCCAAGTTCCACTCTTTCCACCCTGTGGCTACAATTCTCAGTTACCTCAGCAAGGCTCCTCTTGTTCCGCCAGGTACACCCGTGGTGAATGCACTGTCAAAGCAGAGGGCAATGCTGGAGAACATACTGAGGGCTTGTGTTGGTCTGGCTCCAGAGAACAACATGATCTTGGAATACAAGTGA
Protein Sequence
  • >MDP0000207103
    MFIDSFKVXSPNVVYTENEIHSVYSYETTELVHENRNGKYQWIVKPKSIKYEFKTDIHVPKLGVMLVGWGGNNGSTLTAGVIANREGISWATKDXVQQANYFGSLTQASSIRVGSFNGEEIYAPFKSLLPMVKPDDIVFGGWDISDMNLADAMARAKVLDIDLQKQLRPYMESMLPLPGIYDPDFIAANQGARANNVIKGTKKEQLQQVIKDIREFKEKSKVDKVVVLWTANTERYSNVIVGLNDTVENLLGSVDKNDAEISPSTLYAIACVLENVPFINGSPQNTFVPGLIDLAIRRNSLIGGDDFKSGQTKMKSVLVDFLVGAGIKPTSIVSYNHLGNNDGMNLSAPQTFRSKEISKSNVVDDMVSSNGILYGPGEHPDHVVVIKYVPYVGDSKRALDEYTSEIFMGGKSTIVLHNTCEDSLLAAPIILDLVLLAELSTRIQLKSEAEAKFHSFHPVATILSYLSKAPLVPPGTPVVNALSKQRAMLENILRACVGLAPENNMILEYK