Gene Details:
- Gene ID:
- Gene Symbol: MdMIEL1
- Gene Name: MYB30-INTERACTING E3 LIGASE 1
- Genome: Golden ASM211411v1
- Species: Malus domestica
Functional Descriptions:
- MdMIEL1 could mediate the ubiquitination and degradation of MdBBX7 by the 26S proteasome pathway. Genetic interaction analysis suggested that MdMIEL1 acts as an upstream factor of MdBBX7. In addition, MdMIEL1 was a negative regulator of the apple drought stress response.
- Zinc-finger protein MdBBX7/MdCOL9, a target of MdMIEL1 E3 ligase, confers drought tolerance in apple.
- MdMIEL1 targets MdMYB308L, which is a positive regulator of cold tolerance and anthocyanin accumulation.
- MdMIEL1 has a negative effect on drought tolerance.
- Apple RING E3 ligase MdMIEL1 inhibits anthocyanin accumulation by ubiquitinating and degrading MdMYB1 protein.
Function-related keywords:
- drought , stress , drought-stress , tolerance , cold-tolerance , cold-stress , drought-tolerance , cold , stress-tolerance , zinc , stress-response , drought-stress-response , drought-response
Literature:
- Zinc-finger protein MdBBX7/MdCOL9, a target of MdMIEL1 E3 ligase, confers drought tolerance in apple. DOI: 10.1093/plphys/kiab420 ; PMID: 34618120
- Apple RING E3 ligase MdMIEL1 inhibits anthocyanin accumulation by ubiquitinating and degrading MdMYB1 protein. DOI: 10.1093/pcp/pcx129 ; PMID: 29016961
Related News:
Gene Resources:
- NCBI ID: XM_008342616.3
- UniProt accessions:
Sequences:
cDNA Sequence
CDS Sequence
Protein Sequence