Gene Details:
- Gene ID:
- Gene Symbol: MdHDA6
- Gene Name: HISTONE DEACETYLASE 6
- Genome: Golden ASM211411v1
- Species: Malus domestica
Functional Descriptions:
- MdHDA6 can facilitate histone deacetylation and gene repression on the positive drought-responsive genes to negatively regulate drought tolerance in apple. On the other hand, MdHDA6 directly interacts with MdABI5 and represses the expression of genes downstream of MdABI5 via histone deacetylation around these genes to reduce drought tolerance.
- MdHDA6, which negatively regulates apple drought tolerance by catalyzing deacetylation on histones associated with drought-responsive genes.
- MdHDA6 directly interacts with MdABI5 and represses the expression of genes downstream of MdABI5 via histone deacetylation around these genes to reduce drought tolerance.
- Our study uncovers a different drought response regulatory mechanism in apple based on the MdHDA6-MdABI5 complex function and provides the molecular basis for drought-resistance improvement in apple.
Function-related keywords:
- resistance , drought , tolerance , drought-tolerance , drought-resistance , drought-response , transcription-factor , down-regulated-genes
Literature:
- HISTONE DEACETYLASE 6 interaction with ABSCISIC ACID-INSENSITIVE 5 decreases apple drought tolerance. DOI: 10.1093/plphys/kiad468 ; PMID: 37607253
- Histone deacetylase MdHDA6 is an antagonist in regulation of transcription factor MdTCP15 to promote cold tolerance in apple. DOI: 10.1111/pbi.14128 ; PMID: 37475182
Related News:
Gene Resources:
Sequences:
cDNA Sequence
CDS Sequence
Protein Sequence