Gene Details:

Functional Descriptions:

  • A histone deacetylase (MdHDA19) is recruited to the MdERF4–MdTPL4 complex, thereby impacting fruit ethylene biosynthesis. Transient suppression of MdHDA19 expression promoted fruit ripening and ethylene production.
  • MdHDA19 affects ethylene production by facilitating H3K9 deacetylation and forms a complex with MdERF4–MdTPL4 to directly repress MdACS3a expression by decreasing the degree of acetylation.
  • Our results reveal that the MdERF4–MdTPL–MdHDA19 repressor complex participates in the epigenetic regulation of apple fruit ripening.
  • Ethylene response factor MdERF4 and histone deacetylase MdHDA19 suppress apple fruit ripening through histone deacetylation of ripening related genes.

Literature:

Gene Resources:

  • NCBI ID:
  • UniProt accessions:

Sequences:

cDNA Sequence
mRNA Sequence
  • />MD10G1145400
    TTTCCCCATTAAATAAATCAGATATAAATAAAGCAGTTTCCTTACATTGATTTGATGCCCTACCCGCCGATTTAAACCCCCAATAAAAATCTGGTTTCCGCCGACGATGGACACCGGCGGCAACTCTCTAGCGTCGGGTCCCGACGGCGTGAAGAGGAAGGTGAGCTATTTCTACGACCCAGAAGTGGGAAATTACTATTATGGGCAGGGCCACCCGATGAAGCCCCACCGGATTCGGATGACCCACGCCCTCCTCGCCCACTACGGCCTCCTCCAGAACATGCAGGTCCTCAAACCCTACCCGGCCCGCGACCGCGACCTCTGCCGCTTCCACGCCGACGATTACGTGGCGTTCCTCCGGAACATCACCCCGGAAACCCAGCAGGACCAGCTGCGGCAGCTCAAGCGGTTCAATGTCGGCGAGGACTGCCCTGTCTTTGATGGGTTGTACTCGTTTTGCCAGACCTACGCCGGCGGGTCGGTCGGCGGCGCTGTGAAGCTCAACCATGGGATTTGCGACATTTCGATTAATTGGGCTGGAGGTTTGCACCACGCTAAAAAGTGTGAGGCTTCTGGGTTTTGCTATGTGAATGACATTGTTCTTGCAATTTTGGAGCTTCTTAAGCAGCACGAGCGCGTTTTGTATGTGGATATTGATATTCACCATGGAGACGGTGTTGAGGAGGCGTTTTACACGACAGACAGGGTCATGACCGTTTCGTTTCATAAGTTTGGGGATTATTTCCCTGGCACAGGGGACATTCGCGATATTGGGTACGGAAAAGGGAAGTATTACTCCCTTAATGTCCCGTTGGATGACGGGATTGATGATGAGAGCTACCATTACTTGTTCAAGCCCATCATTGGGAAGGTGATGGAAATTTTTAAGCCTGGGGCTGTGGTTCTCCAGTGTGGTGCTGATTCCTTATCTGGAGACAGGCTTGGCTGCTTCAATCTTTCTATCAAAGGTCATGCTGAGTGTGTTAGATATATGAGATCCTTCAACGTCCCGCTCTTGCTTCTAGGTGGTGGTGGCTATACCATTCGCAATGTTGCTCGTTGCTGGTGCTACGAGACAGGAGTAGCACTTGGAGCAGAAATTGAGGACAAAATGCCACAGCACGAGTATTATGAGTATTTTGGTCCAGATTACACTCTTCACGTTGCCCCGAGTAACATGGAAAATAAGAACTCTCATGTGTTACTAGAAGAAATACGGTCAAAGCTTCTTGAAAACCTCTCCACGCTTCAGCATGCACCCAGTGTCCAATTTCAGGACAGACCTCCTGATACTGAGCTTCCGGAGGAGAATGAAGAACAGGATGACCCAGATGAGAGGTGGGATCCAGATTCTGATATGGAGGTTGATGATGAACGTAAGCCTTTACCAAGCAGAGTAAAGAAAGAGATCGTTGAACCTGAGGTTAAAGATCCGAAAGGGACCTCGGAGAATGCTAGAAGCTCAGGCTATGATCCAGCAGTAGATGAGATTACGACAGGAACAAAGGCTTTGGATATGGGCTCTGGATCTGCGGATGAACCAGCTGTGAAGGTTGAACAAGAGACTACGAATAAACCTGCAGACCAGATATAAACGTTATCACGAGCAAATTTATTTGGGGTGACTTTATCACCAAGTCATTCTAACTTATCCATCGCTCGACAAAGAAAAACTTTCAACCGTCCAACGATTTGTGAAGTTGGTAATTTATTTGAGCTGTTGCATTTCATGCATCTTAGCATTTCCTGTATCGTAGTATTTCTTGTATTTGGTAAGAATTCAACGCTTGTTTAAACTTATATGGATAAGTATCCAAATTTGGCAGATGCGTCGATTTGTAATTATACTGTCGTACCTTAAAACTGTATATTTTTGTCGGAACCCTAAAACCGTGTTTATTTCAGGAATCATAATTCCAATCGGTAGTCCTGTCCC
Protein Sequence
  • />MD10G1145400
    MDTGGNSLASGPDGVKRKVSYFYDPEVGNYYYGQGHPMKPHRIRMTHALLAHYGLLQNMQVLKPYPARDRDLCRFHADDYVAFLRNITPETQQDQLRQLKRFNVGEDCPVFDGLYSFCQTYAGGSVGGAVKLNHGICDISINWAGGLHHAKKCEASGFCYVNDIVLAILELLKQHERVLYVDIDIHHGDGVEEAFYTTDRVMTVSFHKFGDYFPGTGDIRDIGYGKGKYYSLNVPLDDGIDDESYHYLFKPIIGKVMEIFKPGAVVLQCGADSLSGDRLGCFNLSIKGHAECVRYMRSFNVPLLLLGGGGYTIRNVARCWCYETGVALGAEIEDKMPQHEYYEYFGPDYTLHVAPSNMENKNSHVLLEEIRSKLLENLSTLQHAPSVQFQDRPPDTELPEENEEQDDPDERWDPDSDMEVDDERKPLPSRVKKEIVEPEVKDPKGTSENARSSGYDPAVDEITTGTKALDMGSGSADEPAVKVEQETTNKPADQI