Gene Details:

  • Gene ID:
  • Gene Symbol: MdHB1
  • Gene Name: homeodomain leucine zipper protein 1
  • Genome: Golden ASM211411v1
  • Species: Malus domestica

Functional Descriptions:

  • MdHB1 down-regulation activates anthocyanin biosynthesis in the white-fleshed apple cultivar ‘Granny Smith’.
  • MdHB1 silencing caused the accumulation of anthocyanin in ‘Granny Smith’ flesh, whereas its overexpression reduced the flesh content of anthocyanin in ‘Ballerina’ (red-fleshed apple).
  • Overexpressing MdHB1 showed a remarkable reduction in pigmentation. Transient promoter activation assays and yeast one-hybrid results indicated that MdHB1 indirectly inhibited expression of the anthocyanin biosynthetic genes encoding dihydroflavonol-4-reductase (DFR) and UDP-glucose:flavonoid 3-O-glycosyltransferase (UFGT).
  • When MdHB1 is silenced, these TFs are released to activate the expression of MdDFR and MdUFGT and also anthocyanin biosynthesis, resulting in red flesh in ‘Granny Smith’.

Literature:

Gene Resources:

Orthologs:

Sequences:

cDNA Sequence
CDS Sequence
Protein Sequence