Gene Details:

Functional Descriptions:

  • Ethylene response factor MdERF4 and histone deacetylase MdHDA19 suppress apple fruit ripening through histone deacetylation of ripening-related genes.
  • We found that MdHDA19 affects ethylene production by facilitating H3K9 deacetylation and forms a complex with MdERF4–MdTPL4 to directly repress MdACS3a expression by decreasing the degree of acetylation.
  • The MdERF4–MdTPL–MdHDA19 repressor complex participates in the epigenetic regulation of apple fruit ripening.
  • A C-to-G mutation in the ethylene-responsive element binding factor-associated amphiphilic repression motif of MdERF4 reduces the repression of MdACS3a by the MdERF4–MdTPL4–MdHDA19 complex.

Literature:

Gene Resources:

  • NCBI ID:
  • UniProt accessions:

Sequences:

cDNA Sequence
mRNA Sequence
  • />MD03G1231800
    ATGGCTCCGACGACGGCGAAGTCCCTACCCAAATCCGGCTCTGAGGACCAGAATCCGACATCCAACGAGATCCGGTACCGGGGTGTCCGGAAGAGGCCTTGGGGACGCTACGCCGCCGAGATCAGAGATCCCGGGAAGAAGACCCGCGTCTGGCTTGGGACCTTCGACACCGCCGAGGAGGCAGCGCGTGCGTACGACAAGGCCGCGCGTGAGTTTCGCGGAGGCAAGGCGAAGACTAACTTCCCCACCCCCTCTGAGCTCCAGCTCGACGCCGTCAACATCGTCAACATGAACAACGCCGCCAAATCAGCGGCGGCGACGAACGTCAGCAACAGTCCCAGCAGCCAGAGCAGCACCGTGGAGTCCTCCTCGCCGCCGCCTCCGCCGCCACTCGACCTCACTCTCAAAAACCCCCGTTTCTCCACCGGCGGCGGCTACTTCACCGCTGCGAGCGGCTTCCGCCCGCTCCCCGTGCCCCGTCCCGTGTTCTTCTTCGACGCCTTCGCACGGGCCGACGGCGCCGCCGCCCTCCAGCTCGCCCGCGAAACTTGCAGGTTCGACCGCCCCGCTCCCATATCCGGCTCGGCCCACAGCGACTCCTCCACGTCCTCGGTCGTCGACTTCGAGCGTAGCTCCCGCAACGTACGGCTCGATCTCGACCTGAACCTCCCAGCCCCCTCGGAAGTCGCCTAA
Protein Sequence
  • />MD03G1231800
    MAPTTAKSLPKSGSEDQNPTSNEIRYRGVRKRPWGRYAAEIRDPGKKTRVWLGTFDTAEEAARAYDKAAREFRGGKAKTNFPTPSELQLDAVNIVNMNNAAKSAAATNVSNSPSSQSSTVESSSPPPPPPLDLTLKNPRFSTGGGYFTAASGFRPLPVPRPVFFFDAFARADGAAALQLARETCRFDRPAPISGSAHSDSSTSSVVDFERSSRNVRLDLDLNLPAPSEVA