Gene Details:

  • Gene ID: MDP0000180420
  • Gene Symbol: MdDEP1
  • Gene Name: Malus domestica dehydratase-enolase-phosphatase complex 1
  • Genome: Golden ASM211411v1
  • Species: Malus domestica

Functional Descriptions:

  • We show that MdbHLH3 also regulates ethylene biosynthesis and leaf senescence by promoting the expression of dehydratase-enolase-phosphatase complex 1 (MdDEP1).
  • Apple dehydratase-enolase-phosphatase complex 1 (MdDEP1), initially characterized as active in the recycling of the ethylene precursor S-adenosylmethionine (SAM), is essential for regulating leaf senescence. Furthermore, MdbHLH3 was shown to mediate leaf senescence via direct activation of MdDEP1 expression.
  • These results support the conclusion that MdDEP1 also plays a key role in leaf senescence in apple.
  • Consistent with its role in the Yang cycle, apple plantlets overexpressing MdDEP1 accumulated a significantly higher amount of methionine.
  • This accumulation may explain the higher ethylene production observed in the MdDEP1 transgenic plantlets compared to the level produced in the WT control.

Literature:

Gene Resources:

  • NCBI ID:
  • UniProt accessions:

Sequences:

cDNA Sequence
CDS Sequence
  • >MDP0000180420
    ATGCAGACAGAAGCGGGAGACGGATATGTGTCGACGGGGAAGTTTGACATAACTGTCGACCAATGTTCCCCATTACAGTTGAAAAAATCCGAAGGCCAGGAGGATCAACATCCTGAACCGGCGAAATGCTTTGTAGAGGGTGAAACTGCACACGTTGAAAGCAAGAACGGTGTCTCAGAGTGCGGAAATCCTTTAGAACCACTCTTAGATCCAAAGGTTGACAAACAAGAGATCTGCGTAGCGGAGAGGCCTCAAGGTGATGAATCAAATCAAGTAGAAACAGGGAATCCACATAGGGAAAATGGAGAAAAAGGAAGTGAAGAGAAGGAAGCCGTGGAGGCAACGGAGAAAAAGTCTGAACATGTTGAGAGTAATGGCATTGTAAATGCTGAAGCAGCGGAAGCATCGAGAAGTAAGACAAACCTTGATGAACACGTTCAAGTAATCTCGGATCAACAGGATTCCGGCATGGGGAAGTCCTTTGCCATGGTGTATGAAGAAAAGGGTCCTGAAGTAACCTCGGAAACTAAAGAAAGCGCTGAGGACAAGCTCGAAAGTGCATCCGTGTTAGATGACCACGAAGAAAAAGCCGGACTTGGAAAGGAAATCCAAGAGAAGAACATCCCAGATACTCCATTACCCACAAAAACAGAAGATATCATTGAGGAGAGTCCAAAAGAAGTTAAGAACCAATACGAAACCTTTGAGGAAACTCCCGAAGCTAGTGGCACTGCAAGTGAAGCAGTTAAGGAGGATGAAAATGCAGAATGCCAGGTTGAAAGTCCATGCATGAAACGTGAGGAAGGTACACTGAAAAAAGGTGAGACACTGGATACAGGAGAGGCTTCAGTGGTGGAGGAGGAAGTTCTTAATGTTTCAACTGTGAAATGTGACGAAGGTGTTCAGGGAGATGGTACCAACCCAACTAAGGATGACAAAGATGTAGACACATTTACCGCCAAAGTGGTTGAAGATGATGACTATACTAGTGCAGTCACCATTACAGTAATGAGCGCAAAAGTAACACCAAATGATGAAGAAAGTTCACCACAGACCTTGCAGAAATGTGATTCAGGAGAGGAGCTTCAACATTTGCGGGATGTGATGCCTGAGGAAACTAAGACAGAAACATCCCGGGAAAATGCAAAAGAAATTACCTGCACGAAAGAGGAAACAACAACTCAGAACACGCAAGAATACTTGGACGAAGAAAAGAAAGAAGCAACTGAAAACACAAACAATCTAGAAGATGACAATGCAAGGGACGAGGTGCTTGATACTGCCGGTGCAGAACAAGAAACTGGAGAACACGTGGTTAGGGAAATTCATACGCTCGCAGAACCACCTCAAGATTTCGTTGATAAAGAAACAAATGAAGAAACCTCCACGGAATATCAGGCATGTACCGAGGCAGCTGATTTGAGTATAAATACAGCGGAAAAGAACTTACAGGAACAGGCCATTCCGGAACTCTCTTCTCCGTTGGTAGTAGAAGAAACAGCCAAGGGAATCCCAAAGGACGAAGAAACCGATGTCTTGATTCTAAAAGAAGAGAAAAAGGAAGAAGATGCAGAATGTAACGAGCCCGCTGAGGCAAAGAGTATGACACGTGAAGCACTACCTGAAACCACAGAGGACATAACAGAGCCAAATAAGGACCTCAATGCTCCAATTTCAGAAGAAAGCAACAAAACATTTGTTGAAAATATTTCCTCTCTCGCTGAGGTATCTGAGACGGAGACTGAGAAAAATATTCAGGAGAAAGATGGCCTCGTGGWTAGCAATTTTGACTCCGTGTCAGGTGAAGTGAGTCATGTAACAKGTTTGAAGGAAGGTGAGACAGAAAATGAGAAACAGAAAGAAAACATTGATGCTGCTCCGGAAGAGAAGGCTCAAACAACCATCTTAAAAGATGAAACGGCCTCAKAAKTTGAAGATATTGGTGTACAAGCAGAGGAAAATTGTGAATCAAAAGAGAAKTTGGAGKASCATATCCCAACAGCAKCAGATGARGGTGAAACATTCTYGRARGAAACCGARGCAGAAAAGGAGCAGATTCCAACAGGCGACTGTGAAACAAGCTTGAACGAAGCCGAAGCTGAAAAGGAGGAGCAGGGCAAAAGTACGGATATTGTTCCGGAAGAGAAGGGTCCGGAAACCATCTTAACAGATGCAACATCCTTGGACGTCGAAGATGTTGAGGTAAAAGCAAAGGACTATGCTGAATCAAAAGAGAACGTGGAGGAGCAGATTCCAATAGCAGCAGATGAAGAAAAACTTACTTATATTTCTCTTGAAGATATTGATGTACAAGCAGAGGAAAATTTCATTACACAAATGAATTTGGAGTACCCGATTCTAACAACCTCAGATGAACAAGAAACAGGCTCGGAAGAAACCAAAGCAGAAATTACGGCGCAGGTGAAAAGTATTGATATTGTTCCTGAAGAGAAGGCTCTAGAAACCATCTCAACAGCTGAGAYACCCTTGGTCGTYGAAGATTTAGGTGTAAAATCAGAGGAAAGTTTCAAATCAAAAGAGAATGTGGAGGAGCAGATTCCAACAGCAGCAGATGAAGAGGAAAAGAGCTTAGAGGAACATGCCATTCAGGAACTCTCTTCTCCGCTGGTAGTAGAAGAAGCAACTAGCGAAATCCCGAAGGAAGAAGAAACCTACACCACGCTTACCACACTTCTAGAAGAAGAGGAAAAGGAAGGGCATGCAACATGTAATGAGGCCACTGAGGAATATGCGGCTGAGATTGAGAAAAATATTCAGGAGAAAGATGGCGCCACACTTAGCAATTCTGAATCTGTGTCTGGAGAACCGACTCATGTAACAATCTTGAAGGAGTCTGAAACAAAGATCAAAATGCAGGGCAAAGACATTGATACTGTTCCTGAAGAGAGGGTTCAAGCAACTATCTTAGCAAATGAAACGGCCTTGGAAGTTGAAGATATTGATGAACAATTAAAGGAGAATTTTGAGTCAAAAGAGAACCTGGAGGAACAATTTCCTATAGCAGCAGATGAAGCTGAAATAGTCTTGAAAAAAGCCGAAGCAGAAAAAAAGGAGCAGATAAAAAATGCTGATATTGCTCATGAAGATGTTGATGTACAAGCGGAGAAAACTGTCAATTCAGAAGAGGACATAGATAAGCAGATTCCACCAATAGCAGATGAAGGCGAAACAAGCTTGAAAGAAGCTGAAGCAGAAATTAAGGAGCAG
Protein Sequence
  • >MDP0000180420
    MQTEAGDGYVSTGKFDITVDQCSPLQLKKSEGQEDQHPEPAKCFVEGETAHVESKNGVSECGNPLEPLLDPKVDKQEICVAERPQGDESNQVETGNPHRENGEKGSEEKEAVEATEKKSEHVESNGIVNAEAAEASRSKTNLDEHVQVISDQQDSGMGKSFAMVYEEKGPEVTSETKESAEDKLESASVLDDHEEKAGLGKEIQEKNIPDTPLPTKTEDIIEESPKEVKNQYETFEETPEASGTASEAVKEDENAECQVESPCMKREEGTLKKGETLDTGEASVVEEEVLNVSTVKCDEGVQGDGTNPTKDDKDVDTFTAKVVEDDDYTSAVTITVMSAKVTPNDEESSPQTLQKCDSGEELQHLRDVMPEETKTETSRENAKEITCTKEETTTQNTQEYLDEEKKEATENTNNLEDDNARDEVLDTAGAEQETGEHVVREIHTLAEPPQDFVDKETNEETSTEYQACTEAADLSINTAEKNLQEQAIPELSSPLVVEETAKGIPKDEETDVLILKEEKKEEDAECNEPAEAKSMTREALPETTEDITEPNKDLNAPISEESNKTFVENISSLAEVSETETEKNIQEKDGLVXSNFDSVSGEVSHVTXLKEGETENEKQKENIDAAPEEKAQTTILKDETASXXEDIGVQAEENCESKEXLEXHIPTAXDEGETFXXETEAEKEQIPTGDCETSLNEAEAEKEEQGKSTDIVPEEKGPETILTDATSLDVEDVEVKAKDYAESKENVEEQIPIAADEEKLTYISLEDIDVQAEENFITQMNLEYPILTTSDEQETGSEETKAEITAQVKSIDIVPEEKALETISTAEXPLVVEDLGVKSEESFKSKENVEEQIPTAADEEEKSLEEHAIQELSSPLVVEEATSEIPKEEETYTTLTTLLEEEEKEGHATCNEATEEYAAEIEKNIQEKDGATLSNSESVSGEPTHVTILKESETKIKMQGKDIDTVPEERVQATILANETALEVEDIDEQLKENFESKENLEEQFPIAADEAEIVLKKAEAEKKEQIKNADIAHEDVDVQAEKTVNSEEDIDKQIPPIADEGETSLKEAEAEIKEQ