Gene Details:

  • Gene ID: MD05G1283600
  • Gene Symbol: MdCacyBP
  • Gene Name: Malus domestica calcyclin-binding protein
  • Genome: Golden ASM211411v1
  • Species: Malus domestica

Functional Descriptions:

  • MdCacyBP interacts with and ubiquitinates MdFRK2 to facilitate its degradation by the 26S proteasome, thus decreasing the FRK enzyme activity to elevate fructose concentration in transgenic apple trees.
  • Further analyses suggested an MdCacyBP–MdFRK2 regulatory module, in which MdCacyBP interacts with and ubiquitinates MdFRK2 to facilitate its degradation by the 26S proteasome, thus decreasing the FRK enzyme activity to elevate fructose concentration in transgenic apple trees.
  • This proposed MdCacyBP–MdFRK2 regulatory module is an important mechanism by which plant fructose homeostasis is controlled at the organ level by regulating MdFRK2 protein levels through ubiquitination and degradation.
  • MdCacyBP ubiquitinated MdFRK2 and accelerated its degradation.
  • MdCacyBP–MdFRK2 regulatory model is crucial for regulating fructose accumulation.

Literature:

Gene Resources:

  • NCBI ID:
  • UniProt accessions:

Sequences:

cDNA Sequence
mRNA Sequence
  • />MD05G1283600
    TTCTTGGAAAAACAAATTTCCCGATCTGCCCCTCCCAACTCCCTCCCCAAGCTTCTAGCATTTTCTGTAACTCCCAAAACATAAGAACCCTTATAAAATTTTACAGTCCGTTTCTCTGGAGAAGGAACTAGCAAACCAAAGCAAGAAAATGGCGGAGGAAGTGGCGCTGGATGTGGAGGAGCTCCGCCACCTTCAGAGCATCGCGAAACGACCCCGGGTTATCGACCTCATTTCCTCTGAGATTCGCACTTTAGAGAAGCAGTTGTCACAAGAGGCTGTTCCTTCACCTGCATTGCAAATCCCAACTCCAGCTTCAACTGCTACTGCCACCCCAGCTCTGCATTACACTACGCTTTCGTCGTTCAGCTGGGACCAGGATAATGATAAAGTGAAGATATACGTTTCTCTGGAAGGAGTTGATCAGGAGAAGATAGAGGCTGACATCAAGCCTATGTCGTTGGACATCAAATTCCATGATGTGGAAGGAAAGAATTACAGGTTCGCTTTGCCTAAGCTGAACAAGGAGATTAATCCAGAGAAGTGTAAGGTGCTGGTTAAGCCTACAAGGGTTGTTATCAATTTGGCTAAAACTTCAAAGGATTACTGGTTGGACTTGAAATTTAAGGAGGATAAGTTGAAGCCGAGTCTGGATAAAGAGAAAGATCCCATGGCTGGAATCATGGACTTGATGAAGAACATGTACGAAGAAGGGGATCCGGAGATGAAGCAAACAATCGCCAAAGCGTGGACCGATGCAAGGCTTGGAAAAACCGGCTGATCTACCGAAGGGGTTTCAACTAATATGGAGCTGAGTCATTGTTTTTGAGTAGTTTTCTTTTGGTTATATGATCTTAATGCTCAGTGAGTTCTTTCGCGGTAGGATGGTTCGTTGTGTTGTTAAGAAACTCTGTTGCACGTAGCTCTTCCAGAGTTCTATATAAAAGATTGAACGGATTTCAGTTTATCAGAGCAGCTTGTGATGGCAACTCGCCGAGTAGCCCTAGTTGATGATCTGATGTGTTTTTGTGGGAATATTGCATTCTGGAATTTAGGGTCTAAATTTTGGTATGGTTCGACTGTGACATTAGGGTTTTGGTGTTTTTGAGGTATATGATATGTGGATGGTTCGCATGTTGGAGTTAGGGTTTAGGGTACCTTTACCACAGTGGTGGAAAATTGATGAGTTCTTGCATGACGATGTGGGTTTAATTCCTATCGGTAACATCTAATATAATAAAATTTAGGAAGTTTTA
Protein Sequence
  • />MD05G1283600
    MAEEVALDVEELRHLQSIAKRPRVIDLISSEIRTLEKQLSQEAVPSPALQIPTPASTATATPALHYTTLSSFSWDQDNDKVKIYVSLEGVDQEKIEADIKPMSLDIKFHDVEGKNYRFALPKLNKEINPEKCKVLVKPTRVVINLAKTSKDYWLDLKFKEDKLKPSLDKEKDPMAGIMDLMKNMYEEGDPEMKQTIAKAWTDARLGKTG