Gene Details:

• Gene ID: MDC029575.23
• Gene Symbol: Md-NBS
• Gene Name: NBS–LRR Protein
• Genome: Golden ASM211411v1
• Species: Malus domestica

Functional Descriptions:

• Analysis of the expression of Md-miRLn11 and Md-NBS during the optimum invasion period in 40 apple varieties showed that the expression of Md-NBS gene in resistant varieties is higher than in susceptible varieties, with an inverse pattern for Md-miRLn11.
• The result showed a clear decline of disease resistance in JiGuan apples. In contrast, the susceptible variety ‘FuJi’ infiltrated with the Md-NBS gene showed a significant increase in disease resistance.
• Based on the above results, we propose that Md-miRLn11 regulates Md-NBS gene expression in particular under the condition of pathogen infection, and that the Md-miRLn11 targeting P-loop site may regulate many NBS–LRR protein class genes in woody plants.
• The novel miRNA, Md-miRLn11, was shown to suppress the expression of the Md-NBS gene and decrease resistance to apple Alternaria leaf spot.

Function-related keywords:

• leaf ,  resistance ,  disease ,  disease-resistance ,  pathogen ,  resistant ,  pathogen-resistance ,  protein

Literature:

• Cloning and characterization of miRNAs and their targets, including a novel miRNA-targeted NBS-LRR protein class gene in apple (Golden Delicious).   DOI:  10.1093/mp/sst101 ;  PMID:  23880633

Related News:

Gene Resources:

• NCBI ID:
• UniProt accessions:

Orthologs:

Sequences: