Gene Details:

Functional Descriptions:

  • The BTB protein MdBT2 was identified as an MdbHLH160-interacting protein that promoted MdbHLH160 ubiquitination and degradation, and ABA treatment substantially inhibited this process.
  • MdBT2 is involved in regulating multiple aspects of growth and development, such as leaf senescence, Fe homeostasis, anthocyanin accumulation, and vacuolar acidification, by mediating the ubiquitination and degradation of various TFs.
  • MdBT2 negatively regulates the low-temperature and drought tolerance of apple by promoting the ubiquitination and degradation of MdMYB23 and MdNAC143.
  • A series of phenotypic analyses indicated that MdBT2 promoted MdCOP1-mediated ubiquitination and degradation of the MdMYB1 transcription factor, inhibiting the expression of anthocyanin biosynthesis genes and anthocyanin accumulation.
  • Apple BT2 protein negatively regulates jasmonic acid-triggered leaf senescence by modulating the stability of MYC2 and JAZ2。
  • BTB-BACK-TAZ domain protein MdBT2-mediated MdMYB73 ubiquitination negatively regulates malate accumulation and vacuolar acidification in apple.
  • BTB/TAZ protein MdBT2 integrates multiple hormonal and environmental signals to regulate anthocyanin biosynthesis in apple.
  • Demonstrated that apple MdBT2 functions as a negative regulator in diverse hormonal and environmental signal-induced anthocyanin biosynthesis, suggesting that MdBT2 integrates stress signals and anthocyanin biosynthesis.

Literature:

Gene Resources:

  • NCBI ID:
  • UniProt accessions:

Sequences:

cDNA Sequence
mRNA Sequence
  • />MD06G1161300
    ATGTTTCTAATATTTAATTTTGATGTTCCAATTCCACTCCCATCTTTCTTTCTCTATAAAGTCAGGCCGACCATCAAACCTCTTCATCCACCCTCATACAAACAAAGCAGCCGGACTCGCAAAAAGCAGACTCCTTCTTTACTCATAGTCTCTCTCTCTCTCTCAATGGAAGCTAATCCGACCGCAACCTCCGGCACCTCCGTCGACCTGTACGGTCTCTCCGGCACCAAATATCTCCCCGAACCCGACGTCGACATCCTCACCTGCGACGCCATCCGCATCCCGGTGCACTCTTGCATCCTGGCCTCAGTGTCGCCGGTGCTGGAGAACATAATCGACCGGCCTCGTAAGCACCGGAGCTCGGAGCGGGTCATTCCGATTCTCGGCGTTCCGTACGACGCCGTATTGGCCTTCGTCCGCTTTCTCTACTCCTCCAGGTGCACAGAAGAGAACATGGAGAAGTACGGGATCCATCTGCTGGCGCTGTCCCACGTGTACTTGGTCCCGCAGCTGAAGAACAGATGCACGAAGGAGCTTGGTCAACGTTTGACCATCGAAAACGTGGTGGACGTGCTGCAACTGGCGAAGATGTGCGATGCAGCGGATCTCTACCTCAAATGCATGAAGTTGGTCGCTAATCACTTCAAGGTTGTTGAGACAACTGAAGGATGGAAATTCTTGCAAGCTCACGACCCTTGGCTCGAACTCCACATCATGCAATTCATCGACGAAATTGAATCGAGGAAGAAGAGGACAAGGAGGCATAGAGAGGAGCAGAGGTTGTATCTCCAGCTGAGTGAGGCAATGGAGTGCTTGGAGCACATATGCAAGGAAGGTTGCACTAGTGTTGGGCCCTACGACATGGAGCCAGGTTACAAGAAGGGCCCATGCAGCAAGTTCTCCACGTGTCAAGGCCTCCAGATGTTGATCCAGCACTTTGCCACGTGTAAGAGGAGGGTGAATGGAGGGTGCTTACGTTGCAAGCGCATGTGGCAGCTTCTTAAGCTTCACTCTTCAATGTGCGAAGAACCTGATTCTTGCAGAGTCCCTCTTTGCAGGCAATTCAAGTTGAAAATGCAGCAAGAGAAGAAGACGGACGATGCCAGGTGGAAACTGCTTGTGAAGAAGGTGATGTCGGCCAAAACCTTATCTTCCCTGTCTCTGCCAAAGAGGAAGAGGGAGGAAGAATTAGGAGAAGGAAGAAGCACTTCTACTATTACTGCTCATGGAATTAGAAGCTTCAGATTGTGATTAATTAGTCGTTAATTAATTATTATATTTAAGTTGGTAGAAAATGGGGTTTAACATTTATTTATTATGTTTAGTTACCAATATTGGGGAAGTATTATCATGTCCAATTTGGTTCCATCATTTATATGTAGTAATTTTTTTGACAATAAATTTCCACTTGTTTTGGTTACATTTATCTCATCTTTAATATTATGATAAATTCGTAAATTCGTAA
Protein Sequence
  • />MD06G1161300
    MFLIFNFDVPIPLPSFFLYKVRPTIKPLHPPSYKQSSRTRKKQTPSLLIVSLSLSMEANPTATSGTSVDLYGLSGTKYLPEPDVDILTCDAIRIPVHSCILASVSPVLENIIDRPRKHRSSERVIPILGVPYDAVLAFVRFLYSSRCTEENMEKYGIHLLALSHVYLVPQLKNRCTKELGQRLTIENVVDVLQLAKMCDAADLYLKCMKLVANHFKVVETTEGWKFLQAHDPWLELHIMQFIDEIESRKKRTRRHREEQRLYLQLSEAMECLEHICKEGCTSVGPYDMEPGYKKGPCSKFSTCQGLQMLIQHFATCKRRVNGGCLRCKRMWQLLKLHSSMCEEPDSCRVPLCRQFKLKMQQEKKTDDARWKLLVKKVMSAKTLSSLSLPKRKREEELGEGRSTSTITAHGIRSFRL