Gene Details:

• Gene ID: MD00G1130200
• Gene Symbol: MdbHLH3-27
• Gene Name: Malus domestica basic helix–loop–helix 3
• Genome: Golden ASM211411v1
• Species: Malus domestica

Functional Descriptions:

• MdbHLH3 regulates soluble sugar accumulation by activating MdPFPβ gene expression and coordinating carbohydrate allocation.MdbHLH3 directly modulates auxin signaling in controlling leaf shape in response to local spatial gradients in apple.
• MdbHLH3 directly regulates the expression of cytosolic malate dehydrogenase MdcyMDH to coordinate carbohydrate allocation and malate accumulation in apple.
• MdbHLH3 modulates apple soluble sugar content by activating phosphofructokinase gene expression.
• MdbHLH3, binds to the MdPFPβ promoter and activates its expression, thus promoting soluble sugar accumulation in apple fruit.
• MdbHLH3 promotes sucrose, fructose, and F6P accumulation throughout fruit development by regulating enzyme activities in sugar metabolism.
• MdbHLH3 promotes F6P and sucrose accumulation by activating MdPFPβ expression.

Function-related keywords:

• leaf ,  development ,  leaf-development ,  auxin ,  auxin-response ,  leaf-shape ,  sugar ,  sucrose ,  dehydrogenase ,  carbohydrate-metabolism ,  fructose ,  fructose-accumulation

Literature:

• MdbHLH3 modulates apple soluble sugar content by activating phosphofructokinase gene expression.   DOI:  10.1111/jipb.13236 ;  PMID:  35199464
• A basic/helix-loop-helix transcription factor controls leaf shape by regulating auxin signaling in apple.   DOI:  10.1111/nph.16828 ;  PMID:  32712992
• The apple bHLH transcription factor MdbHLH3 functions in determining the fruit carbohydrates and malate.   DOI:  10.1111/pbi.13461 ;  PMID:  32757335

Related News:

• JIPB | 山东农业大学胡大刚课题组发现苹果转录因子调控可溶性糖积累新机制
• New Phytologist | 山东农业大学郝玉金教授课题组在苹果叶形调控研究方面取得进展
• PBJ|山东农业大学郝玉金教授团队揭示碱性螺旋-环-螺旋bHLH转录因子MdbHLH3调控苹果果实品质的机理研究

Gene Resources:

• NCBI ID:
• UniProt accessions:

Sequences: