Gene Details:

Functional Descriptions:

  • The regulatory module MdPUB29-MdbHLH3 connects ethylene biosynthesis with fruit quality in apple.
  • Overexpression of apple MdbHLH3 gene, an anthocyanin-related basic helix–loop–helix transcription factor (bHLH TF) gene, promotes ethylene production, and transgenic apple plantlets and trees exhibit ethylene-related root developmental abnormalities, premature leaf senescence, and fruit ripening.
  • MdbHLH3 regulates ethylene- and ripening-associated genes in fruits.
  • ABI5 regulates ABA-induced anthocyanin biosynthesis by modulating the MYB1-bHLH3 complex in apple.
  • The basic helix-loop-helix transcription factor MdbHLH3 modulates leaf senescence in apple via the regulation of dehydratase-enolase-phosphatase complex 1.
  • The bHLH transcription factor MdbHLH3 promotes anthocyanin accumulation and fruit colouration in response to low temperature in apples.
  • The MdbHLH3 protein was post-translationally modified, possibly involving phosphorylation following exposure to LTs, which enhanced its promoter-binding capacity and transcription activity.

Literature:

Gene Resources:

Sequences:

cDNA Sequence
CDS Sequence
  • >MDP0000225680
    ATGGCTGCACCGCCGCCAAGCAGCAGCCGCCTCCGCGGTATGTTGCAGGCCTCAGTTCAATATGTCCAATGGACTTACAGTCTCTTCTGGCAAATCTGTCCCCAACAAGGGATCTTAGTATGGTCAGATGGGTACTATAATGGAGCTATCAAGACGAGGAAGACAGTGCAACCAATGGAAGTGAGTGCCGATGAGGCATCTCTCCAGAGGAGCCAGCAACTCAGAGAACTCTACGACTCTTTGTCCGCTGGAGAGACAAACCAGCCCCCAGCACGCCGCCCTTGCGCTTCCTTGTCCCCGGAGGACTTAACCGAATCTGAATGGTTCTACTTGATGTGCGTCTCATTCTCCTTTCCCCCCGGCGTCGGGTATTGTCGATCAGTACTAACAACTACCGCAAATAAAATCTTTGATTATCTAAAATGGGCTCACTTTCTGACTAGAGGGCACACTGTAAATGTCCGGAACTGTATTTCTTCAAAAGATGAAATATTATTTAGCTACACGAGTAAGGCTGTGGGTAAGTGCGAAAGAGTGCATCTTGGCACATGTGGTTCTCTGGAGAGAAAGTTGCCAGGGAAAGCATACGCAAGGAGGCAGCATGTATGGCTCACCGGTGCAAACGAGGTCGATAGCAAAACCTTTTCCAGAGCTATTTTGGCAAAGAGTGCTCGTATACAGACCGTGGTGTGCATTCCTCTTCTAGATGGCGTCGTAGAATTTGGCACCACAGAGAGGGTTCCAGAAGACCACGCCTTCGTCGAACACGTCAAAACCTTCTTCGTTGACCACCACCACCCTCCGCCACCAAAACCCGCCCTCTCCGAGCACTCCACATCCAACCCCGCCGCCTCATCCGATCACCCACATTTCCACTCTCCGCACCTTCTCCAGGCCATGTGCACCAACCCTCCTCTCAACGCCGCCCAAGAAGACGAAGAGGACGAAGAAGAAGATGATAATCAGGAGGAGGACGACGGAGGAGCCGAGTCCGACTCCGAAGCCGAAACGGGCCGCAATGGTGGAGCCGTTGTTCCCGCCGCAAACCCTCCTCAGGTTTTGGCCGCGGTAGCCGAGCCAAGCGAGCTCATGCAACTCGAGATGTCCGAAGACATCCGGCTAGGCTCCCCGGACGATGCCTCAAATAACTTGGACTCTGATTTCCACTTGTTAGCTGTGAGTCAGTCTAGGAACCCAGCGGATCAGCAGAGACAAGCTGACTCGTATCGAGCCGAGTCGACCAGGCGGCGTCCGTCAGTACAAGAGCCGCTGAGCAGTGGCCTTCAACCGCCGCACACAGGACCCCTAGCTTTAGAGGAGTTGACACATGATGACGACACACATTACTCGGAGACAGTCTCCACCATACTGCAGGGACAGGTGACTCAGTTGATGGATTCATCGTCCACCGACTACACAGCTTGCTTGACTCAATCAGCTTTCGCCAAGTGGTCGAGCCGGGTTGATCACCACTTCCTCATGCCGGTTGAAGGCACGTCCCAATGGCTCTTGAAATATATTTTGTTTAGTGTACCGTTCCTCCACTCAAAATATCGCGACGAGAACTCGCCAAAATTTCAGGAGGGCGAAGGCTCGACACGGTTGAGGAAAGGGACCCCACAAGACGAGCTCAGTGCTAATCATGTGTTAGCGGAACGACGTCGTAGAGAGAAGCTTAATGAGAGGTTTATTATACTAAGGTCCCTGGTGCCTTTTGTGACAAAAATGGACAAGGCTTCGATATTAGGAGACACAATCGAGTATGTAAAGCAACTGCGTAACAAAATTCAGGATCTCGAGGCACGTAACATGCTGGTGGAGGAAGATCAACGGTCAAGATCATCCGGGGAAATGCAAAGGTCCAATAGTTGTAAAGAGTTGCGAAGTGGGCTCACGCTAGTGGAGCGGACCCAAGGAGGTCCACCCGGGTCCGATAAAAGGAAGTTGAGGATTGTGGAGGGAAGTGGCGGTGTCGCCATTGGTAAGGCTAAAGTAATGGAGGACTCACCGCCTTCACCACCCCCGCCACCACCTCAGCCAGAACCTTTACCGACACCTATGGTGACGGGGACTTCTCTAGAGGTGTCGATAATCGAGAGTGATGGGTTGTTGGAGCTCCAGTGCCCGTATAGAGAAGGGTTATTGCTTGATGTGATGCGAACACTTAGGGAGCTAAGAATTGAGACCACGGTGGTCCAGTCCTCATTGAATAACGGATTTTTCGTAGCTGAACTAAGAGCCAAGGTGAAGGATAACGTCAGTGGCAAGAAAGTAAGTATAACGGAAGTGAAGAGGGTGATAAATCAAATTATACCCCAATCTGACTCTTAA
Protein Sequence
  • >MDP0000225680
    MAAPPPSSSRLRGMLQASVQYVQWTYSLFWQICPQQGILVWSDGYYNGAIKTRKTVQPMEVSADEASLQRSQQLRELYDSLSAGETNQPPARRPCASLSPEDLTESEWFYLMCVSFSFPPGVGYCRSVLTTTANKIFDYLKWAHFLTRGHTVNVRNCISSKDEILFSYTSKAVGKCERVHLGTCGSLERKLPGKAYARRQHVWLTGANEVDSKTFSRAILAKSARIQTVVCIPLLDGVVEFGTTERVPEDHAFVEHVKTFFVDHHHPPPPKPALSEHSTSNPAASSDHPHFHSPHLLQAMCTNPPLNAAQEDEEDEEEDDNQEEDDGGAESDSEAETGRNGGAVVPAANPPQVLAAVAEPSELMQLEMSEDIRLGSPDDASNNLDSDFHLLAVSQSRNPADQQRQADSYRAESTRRRPSVQEPLSSGLQPPHTGPLALEELTHDDDTHYSETVSTILQGQVTQLMDSSSTDYTACLTQSAFAKWSSRVDHHFLMPVEGTSQWLLKYILFSVPFLHSKYRDENSPKFQEGEGSTRLRKGTPQDELSANHVLAERRRREKLNERFIILRSLVPFVTKMDKASILGDTIEYVKQLRNKIQDLEARNMLVEEDQRSRSSGEMQRSNSCKELRSGLTLVERTQGGPPGSDKRKLRIVEGSGGVAIGKAKVMEDSPPSPPPPPPQPEPLPTPMVTGTSLEVSIIESDGLLELQCPYREGLLLDVMRTLRELRIETTVVQSSLNNGFFVAELRAKVKDNVSGKKVSITEVKRVINQIIPQSDS