Gene Details:

• Gene ID: MDP0000825749
• Gene Symbol: MdbHLH104
• Gene Name: basic helix-loop-helix transcription factor 104
• Genome: Golden ASM211411v1
• Species: Malus domestica

Functional Descriptions:

• The SUMO E3 Ligase MdSIZ1 Targets MdbHLH104 to Regulate Plasma Membrane H+-ATPase Activity and Iron Homeostasis.
• MdbHLH104 (a homolog of Arabidopsis bHLH104 in apple), which acts as a key component in regulating PM H+-ATPase-mediated rhizosphere acidification and Fe uptake in apples (Malus domestica), was identified as a direct target of MdSIZ1.
• MdbHLH104, an upstream regulator of the PM H+-ATPase gene MdAHA8 was identified via yeast two-hybrid as an MdSIZ1-interacting protein.
• Overexpression of MdbHLH104 gene enhances the tolerance to iron deficiency in apple.
• MdbHLH104 acts together with other apple bHLH TFs to regulate Fe uptake by modulating the expression of the MdAHA8 gene and the activity of PM H+-ATPase in apple.

Function-related keywords:

• atpase ,  homeostasis ,  plasma-membrane ,  iron ,  fe ,  iron-homeostasis ,  fe-homeostasis

Literature:

• The SUMO E3 Ligase MdSIZ1 Targets MdbHLH104 to Regulate Plasma Membrane H(+)-ATPase Activity and Iron Homeostasis.   DOI:  10.1104/pp.18.00289 ;  PMID:  30333149
• Overexpression of MdbHLH104 gene enhances the tolerance to iron deficiency in apple.   DOI:  10.1104/pp.18.00289 ;  PMID:  26801352

Related News:

• 山东农业大学发现苹果铁素营养平衡调控新机制

Gene Resources:

• NCBI ID:
• UniProt accessions:

Sequences: