Gene Details:

  • Gene ID: MD14G1021600
  • Gene Symbol: MdABI5
  • Gene Name: Malus domestica ABSCISIC ACID-INSENSITIVE 5
  • Genome: Golden ASM211411v1
  • Species: Malus domestica

Functional Descriptions:

  • MdHDA6 interacted with the abscisic acid (ABA) signaling transcriptional factor, ABSCISIC ACID-INSENSITIVE 5 (MdABI5), forming the MdHDA6-MdABI5 complex.
  • Interestingly, MdHDA6 facilitated histone deacetylation on the drought-responsive genes regulated by MdABI5, resulting in gene repression.
  • Our study uncovers a different drought response regulatory mechanism in apple based on the MdHDA6-MdABI5 complex function and provides the molecular basis for drought-resistance improvement in apple.
  • MdHDA6 can facilitate histone deacetylation and gene repression on the positive drought-responsive genes to negatively regulate drought tolerance in apple. On the other hand, MdHDA6 directly interacts with MdABI5 and represses the expression of genes downstream of MdABI5 via histone deacetylation around these genes to reduce drought tolerance.
  • The MdABI5 transcription factor interacts with the MdNRT1.5/MdNPF7.3 promoter to fine-tune nitrate transport from roots to shoots in apple.
  • ABI5 regulates ABA-induced anthocyanin biosynthesis by modulating the MYB1-bHLH3 complex in apple.

Literature:

Gene Resources:

Sequences:

cDNA Sequence
mRNA Sequence
  • />MD14G1021600
    TCAAGTGTAGATCGCACAAACATGGGTGTTTTGGAGTCGGAAATCAACTCTCATGGCGAGGTGGATTCGCCCTTGTTATCGGACCAACAAGCGAAGAACCACTTATTCTCCTCATTAGGAAGACAATCATCAATCTACTCGCTCACTCTTGATGAGTTTCAGCACACACTCTGCGAGAGCGGCAAGAATTTCGGGTTGATGAATATGGATGAGTTCCTAACCAGCATTTGGACCGCCGAAGAAAACCAAGCCATTAATTCCAATCTCACCAACACTACTACTACTAACAACAACAACAACATGAACAACATTGAGGTGCACATACCTTTAGCCGAGGCCTCAGCAGAAAAGAGCATTGCGACGCAGCCCAGCTTGCCGCGTCAAGGCTCGCTTACGCTGCCTGAGCCACTGTGTAGGAAAACAGTGGATGAAGTTTGGTCTGAGATAAACGGAGGGCAGCAGGCAAAGCAGCAGAACAATCACAACAGTAGCATCGATGGTAGTGTTCAGAGTTCTGAGTTTGCCCCTCGCCAGCCTACTTTTGGGGAGATGACATTGGAGGATTTTTTGGTTAAAGCAGGGGTAGTTCGGGAACAGGATTCAATGGCAGCCACGGTGGTCCCTCCTCAGCCTCACCAGCAGCAGCGGTATGGGATGTACCAGAACGGCAACCATGCTGTGGGACCCAGTTTTGTTAATAGGCCTGTGATGGGAATGGGGGCTGCTGCCGCAGCAGGTGCTAGTACTAGCACTGCCGCCGGTATTCCTAATTACCAAACTATACCGCAAAGTGGGGCTGCGGTTGTGGGAGAGTCCTCTGCGTATGCTGCGAATGGTAAGAGGAATGGGGCGTACCCGGGCGTGCGGCCTCCACAGTCGGTTTGTTTTGGCGGGAGAGTGGAGAATGGTGGTGGTGGATATGCAGCAGGGCAGACAATTGGGATGGCGGCTCCGGGGAGTCCGGTGTCTTCAGATGGGATGGGTACTAGTCAGGTTGAAAACTCTGCGGGTAGATTTGGTTTGGACATGGGTTTAGATGGACTAAGAGGAAGGAAACGGGGTTTAGATGGACCGGTCGAAAAAGTGGTGGAGAGGAGGCAGAGAAGGATGATTAAGAACAGAGAGTCTGCAGCAAGGTCTAGAGCTCGAAAACAGGCATACACAGTTGAATTGGAAGCAGAACTGAACCACTTACGAGAAGAGAACTCACACCTTAAACAGGCGCTGAGCTCGAGAGGAAGCGAAAGCAACAGTATTTCGAGGAAATGAAGATGAGAGTTCAGAACAGGGCCCAGAAAGTGAAGGAGAAGCTAAGGGTGTTGAGGAGGAGTAATAGTTGTGTTTTATAATGTGCAATCTGAGATATGAACTGAAGCCCTCGCCGAGGGAAGTCGAAACTGTGCAAGCTCAGCTCAATGCTGAAACGGCTACAAGGTGAAGCAAGAGTGCTACACTGCAAGATAAGATGATGCCACTATGAGAATAAATGTGAATGATTCCTGTAGTAGGCATGATTATATACGTTTGTTGTAGTTTTTGTATATTTC
Protein Sequence
  • />MD14G1021600
    MGVLESEINSHGEVDSPLLSDQQAKNHLFSSLGRQSSIYSLTLDEFQHTLCESGKNFGLMNMDEFLTSIWTAEENQAINSNLTNTTTTNNNNNMNNIEVHIPLAEASAEKSIATQPSLPRQGSLTLPEPLCRKTVDEVWSEINGGQQAKQQNNHNSSIDGSVQSSEFAPRQPTFGEMTLEDFLVKAGVVREQDSMAATVVPPQPHQQQRYGMYQNGNHAVGPSFVNRPVMGMGAAAAAGASTSTAAGIPNYQTIPQSGAAVVGESSAYAANGKRNGAYPGVRPPQSVCFGGRVENGGGGYAAGQTIGMAAPGSPVSSDGMGTSQVENSAGRFGLDMGLDGLRGRKRGLDGPVEKVVERRQRRMIKNRESAARSRARKQAYTVELEAELNHLREENSHLKQALSSRGSESNSISRK