Gene Details:

Functional Descriptions:

  • CYTOKININ OXIDASE/DEHYDROGENASE5 (MdCKX5), an age-dependent gene, encodes a functional CKX enzyme and serves as the common downstream target of SQUAMOSA PROMOTER BINDING PROTEIN-LIKE (SPL) transcription factor MdSPL14 and WRKY transcription factor MdWRKY24 to control the degradation of cytokinin (CK).
  • As the target of mdm-microRNA156a, MdSPL14 interacts with MdWRKY24 to coordinately repress the transcription of MdCKX5 by forming the age-mediated mdm-miR156a–MdSPL14–MdWRKY24 module, which regulates age-dependent changes in CK during the juvenile-to-adult phase transition.
  • Molecular and biochemical studies indicated that MdCKX5 plays an important role in controlling CK levels via the age-mediated mdm-miR156a–MdSPL14–MdWRKY24 module.
  • MdCKX5 expression in the leaves and roots was significantly upregulated after tZ and iP treatment, indicating that the expression of MdCKX5 was strongly induced by exogenous CK. These findings demonstrated that MdCKX5 degrades active CKs in apple.

Literature:

Gene Resources:

Orthologs:

Sequences:

cDNA Sequence
mRNA Sequence
  • />MD15G1021500
    GCACAGAGTCAGAATCTCAGAATCTCTGGATGATTTGTTGTTTGTTGCCTCGGAAAATTGTAGAGTGAGAGAGAAAATATTTACAGATATACATATATTCCTCGTTACCTTATCTGCTAAAATATTATATAGTATATCTAGATAGATATTATTCACACAGTACATGTATGTATGTGAGTGTACCTGCAGTCTTGTAACGTGAAGAAATCTTGTTCTGGAAAAGAAAGAAAGAAAGAGGAGCTGAGCGAATCTGTGCATGTTGCGTACGAAATCTTTAAAGCGAAATCAGCCTTACGTTATCTCCACGACCACACATCCCTCCCTCCCTCTGACACAAAGATTTTGTTCCTTCTCATGTTTCTCTTATTTATTTCGTTAATTCCTTCCTCTCACGGTCTCACTCACTATAGTCTATATATAGCTAGACTATAGCTGGATACCACCACCGCCACCTACTTCTCTCCGCCGTTGTCCACAGTTCTCAAATCCTTCATCCTTCTAGCCGCCGCCTCCTCCTCCTCCTCCAGTATGTAATCCTATACCTAATTCATCATTTTAAACCAAACAAAGAAAATCAAGATCAAGAACAAGAACAAGAATAGTAACGTACTTGAACACATGGCAACTACCAAGCTTGTTTTAATTACATTCGCAATCTGTCGACTTATTCTCACGGTTGGTTTAACCGTGGATCCAACGGAGCTTCTCCGCCTCGTCGTCGACGGACAGCTCAGTGTAGACCCATCTGACGTGGATACCGCTTCGAAAGATTTCGGCCTGATGAGCAGAGCGGCGCCCTTGGCCGTTTTACACCCTGCCTCCGCCCAAGACGTGGCGGGACTGGTGCGGGCAGCCTACTCTTCGCCGCACGGGTTCACGGTCTCGGCCAGAGGCCACGGGCACTCCATCAACGGGCAGGCGCAGACCAACAACGGTGTCGTGATTCAGATGAGCGGGGGATCGTTGAGATCGGGGAGGCCGGCTCAGGCGGCTCGAGTATCGGAGAAGGGGATGTATGTTGATACGTGGGGTGGGGAGTTGTGGATAGATGTGCTCAGGAGCACGCTGGAGTATGGACTCGCACCGAAGTCGTGGACTGATTATTTGTACTTAACAGTCGGAGGAACCCTTTCCAACGCCGGAATCAGCGGCCAAGCTTTCAATTATGGACCTCAGATTAGTAATGTTCATGAGCTCGACGTTGTTACAGGCAAAGGCCAGCTATTGACATGTTCCGAAGAGCAAAACTCAGAGCTGTTCCAGGCTGTTCTTGGTGGGCTAGGCCAGTTTGGAATCATCACTAGGGCTAGAATTGCTCTCGAACCATCCCCCAAAAGGGTGAGGTGGATCCGAGTACTGTATTCCAATTTTTCGGCTTTTACCAAAGACCAGGAATTCCTCATCTCTCTGCATGGGCAACCTTCCAGCCAGAAATTCGACTATGTCGAGGGTTTCGTTATTGTCGACGAAGGCCTCATCAACAATTGGAGGTCATCTTTCTTCTCCGCTAGCAACCCTGTTAAAATCACCTCCATTGATTCTGAAGGTGGTGTTTTATATTGCTTGGAGATTACGAAAAATTACGACGAATCGACTGCCGATACAATTGACAAGGAAATAGAGGATTTGTTGGAAAAACTGGATTTTGTACCGACGTCAGTCTTCACAACTGATCTTCCATACGTGGATTTTCTGGACCGCGTTCACAAGGCCGAGTTGAAGCTCCGAGCCAAGGGTTTGTGGGACGTCCCCCATCCATGGCTTAACCTTTTTGTCCCCAAATCAAGGATTTCTGACTTCAACGAAGGAGTGTTCAAGGGCATTTTGGGAAATAAGACAAGCGGACCCATTCTGATTTACCCCATGAACAAAGACAAGTGGGACCAGAGTAGCTCGGTGGTGACGCCCGACGAGGACATTTTTTACCTTGTGGCGCTGCTAAGAACTGCCTTGGATACCGGGGACGAGACCCACACCTTGGAGCACCTGACCAATCAGAACCGTCAGATCCTCAGATTCTGTGTTGATGCGGGGATCGAGGTGAAACAGTACCTCCCGCACTATACTACGCAGGAGGAGTGGATGGACCACTTTGGAGATAAGTGGGCCCGGTTTTACAAGAGGAAGATGGAGTTCGACCCTCGGCGCATTTTAGCCACCGGCCAACGTATTTTCAGCCCTTCATCGGTTTCTTCTAGTCTTGGTGTTGGTGGTGATAAATTGTCGATTTCTTAGATGACCAAAACGTGCAGTTTTTAGGGTTAGTCTTGTACATATACTGTTAGATGAACTCTTTTTTATTATCAAATGAGTACTGGTTATTATAAAGAAAACGAGGTTTTGTTTAGGGGTTTTTCAGTCTGAATGCTCAGATCACGTGACTGTTCAGGCTCCAGCCGAGGCCCAAGACTCATTGTGTGGAACTAGGATAGTGTTGATGGGGCCGGAATACAGTAGTGGAACGAGATACAATGTTTTTGTGCCTTTGGTTGTAGAGGTGAGGTGGCATGACCACCCGTATTCAAGAATTTCTCCTTTTTTAGGGTTTGTTCAGTGAGAGCGATGCACCCGAATGGGGCCCACGATCACAATGTTTTTGTATGCAGCGCCCGTGATCCGGACAGCCCAGTCTGGTTTTGTTCTGGGACTTGACGTCTTTATCCGCAACCTCATCCAACACAAGCTGGATTCTGATCATCACTCCATCATCCTTCATGGTTTGTCAATTACTGTTATACCCTTCTTCGATTGGTCGCTAGGTAGAAGTCG
Protein Sequence
  • />MD15G1021500
    MATTKLVLITFAICRLILTVGLTVDPTELLRLVVDGQLSVDPSDVDTASKDFGLMSRAAPLAVLHPASAQDVAGLVRAAYSSPHGFTVSARGHGHSINGQAQTNNGVVIQMSGGSLRSGRPAQAARVSEKGMYVDTWGGELWIDVLRSTLEYGLAPKSWTDYLYLTVGGTLSNAGISGQAFNYGPQISNVHELDVVTGKGQLLTCSEEQNSELFQAVLGGLGQFGIITRARIALEPSPKRVRWIRVLYSNFSAFTKDQEFLISLHGQPSSQKFDYVEGFVIVDEGLINNWRSSFFSASNPVKITSIDSEGGVLYCLEITKNYDESTADTIDKEIEDLLEKLDFVPTSVFTTDLPYVDFLDRVHKAELKLRAKGLWDVPHPWLNLFVPKSRISDFNEGVFKGILGNKTSGPILIYPMNKDKWDQSSSVVTPDEDIFYLVALLRTALDTGDETHTLEHLTNQNRQILRFCVDAGIEVKQYLPHYTTQEEWMDHFGDKWARFYKRKMEFDPRRILATGQRIFSPSSVSSSLGVGGDKLSIS