Gene Details:

• Gene ID: MD14G1040300
• Gene Symbol: MdPUB23
• Gene Name: U-box-type E3 ubiquitin ligase
• Genome: Golden ASM211411v1
• Species: Malus domestica

Functional Descriptions:

• Apple U-box-type E3 ubiquitin ligase MdPUB23 reduces cold-stress tolerance by degrading the cold-stress regulatory protein MdICE1.
• MdPUB23, positively regulated the cold-stress response in apple, overexpression of MdPUB23 in transgenic apple enhanced sensitivity to cold stress.
• MdPUB23 directly interacted with MdICE1, promoting the ubiquitination-mediated degradation of the MdICE1 protein through the 26S-proteasome pathway and reducing the MdICE1-improved cold-stress tolerance in apple.
• The PUB23–ICE1 ubiquitination module may play a role in maintaining ICE1 protein homeostasis and preventing overreactions from causing damage to plants.

Function-related keywords:

• stress ,  tolerance ,  cold-tolerance ,  cold-stress ,  cold ,  stress-tolerance ,  homeostasis ,  ubiquitin ,  stress-response ,  ubiquitin-e3-ligase ,  protein

Literature:

• Apple U-box-type E3 ubiquitin ligase MdPUB23 reduces cold-stress tolerance by degrading the cold-stress regulatory protein MdICE1.   DOI:  10.1093/hr/uhac171 ;  PMID:  36247364

Related News:

Gene Resources:

• NCBI ID:
• UniProt accessions:

Orthologs:

Sequences: