Gene Details:
- Gene ID: MD05G1189400
- Gene Symbol: MdPHR1
- Gene Name: PHOSPHATE STARVATION RESPONSE1
- Genome: Golden ASM211411v1
- Species: Malus domestica
Functional Descriptions:
- determined that MdPHR1 was essential for Pi deficiency-induced anthocyanin accumulation in apple (Malus × domestica).
- MdPHR1 interacted with MdWRKY75, a positive regulator of anthocyanin biosynthesis, to enhance the MdWRKY75-activated transcription of MdMYB1, leading to anthocyanin accumulation.
- The protein kinase apple BRASSINOSTEROID INSENSITIVE2 (MdBIN2) phosphorylated MdPHR1 and positively regulated MdPHR1-mediated anthocyanin accumulation by attenuating the MdSINA1-mediated ubiquitination degradation of MdPHR1.
- Taken together, these findings not only demonstrate the regulatory role of MdPHR1 in Pi starvation induced anthocyanin accumulation, but also provide an insight into the post-translational regulation of PHR1.
Function-related keywords:
- kinase , brassinosteroid , protein-kinase , transcription-regulator , brassinosteroid-biosynthesis , pi , anthocyanin-biosynthesis , anthocyanin , protein
Literature:
- The E3 ubiquitin ligase SINA1 and the protein kinase BIN2 cooperatively regulate PHR1 in apple anthocyanin biosynthesis. DOI: 10.1111/jipb.13538 ; PMID: 37272713
Related News:
Gene Resources:
Orthologs:
Sequences:
cDNA Sequence
mRNA Sequence
- />MD05G1189400
GCAAAAATTGATGACCCCTTTCGGTGGTTTTGCTGTCAATAACAAGCAAAAGGTGCGCAGTCAGTAAGGTTGAAGTTGGACTATAGATGGAGGCACGCCCTGCTATGTCCATCCGGAGATCGGCTGCAAATCAGCTTGCTCATATGGGGGTCCCTGCAGCAATGTCTTCATCCTTACCAGTCCTTCCAACTTCTTTGGAAGAGACACATCCCAATTTACCAGACTCCCAACAGGTTTCCATGGAAAGAGAACTTATGACAAGGCCTGTTGTGCATGCTGGTCACTTAACCTCCAACAGTGGAGTAGTTGGTCACATATTTTCATCATCGTCGGGATTTTCAACAGATCTTCACTACTCAACTCATTCACCTCATGAAAAACAGCAAAAAAACTCTCCTTTCATTTCTCAGTCTCCTCATTCGGGATTTCTTCAGTCAACAGAATCTTGTCCTTATCCCAAAGAAAACAGTGGTTCCTGGTGTACAGATCCACTGCCAGGTTTCCTTGATTTTCCTGTAAATAACCATATCGAGAATAGTCAAATAGAGAGCAGTAGTTGTAGCGGCATAATGGCTGCTGATGAATTTGCTAAGCGACATGATTGGCAGGAATGGGCAGATCAGCTAATTACTGATGACGATGCTTTAACTTCTAACTGGAATGAGCTTCTTGTTGACAACGTTACAGATCTGGAACAAAAGATGAAATACCAGGCTCCCAAACCGTCTCCAAATTTTTCGGTCCAGCAGTCCCAAGTTCATCAGCAACAACCTGCTTCATCTGGGGAAATCATTCCTGCTCCATCTAGGGAAATCATTTCTGTTACTGCTCCTTCTTCAGCTAATAGTGCCACTGCCAAGGCACGCATGCGTTGGACGCCTGAACTTCATGAGTCCTTTGTGGAGGCTGTTAACCAACTTGGCGGTAGTGAAAGAGCAACTCCTAAGGGTGTGCTAAAGCTCATGAAAGTTGAACACTTGACTATCTATCATGTGAAAAGTCACTTGCAGAAATATAGGACTGCTAGATACAGACCAGAATCATCCGAAGGCGCCTCAGAGAAGAAATTGACTCCAATTGAAGAAATGACGTCTCTTGACTTGAAAACTGGTATCGAGATCACTGAAGCTCTGCGACTGCAGATGGAAGTTCAGAAGCGACTGCATGAACAGCTTGAGATTCAAAGAAATCTGCAGTTACGAATAGAAGAACAAGGGAAGTATCTTCAAATGATGTTTGAGAAGCAATGCAAGTCAGGCATCGACACGCTGAACCCATCATCATCCAATTTGGACGACCCCTCCGCTCAGCCTTCAGATGCAACGCAAGTTTGTCTCGACAAAAGTGAACCGGAGTCTTCCAAGTTGGGCCAAGGCGAGACTCAAACTGATCCAGTTAAAGCCAACTCCACATCATCAGGTGGTTCACAGGAACCGGAAGGGAAGCAGAAGGCACCTGAAACGGAAACTGTTCCCCAGAATCCCGAGCCAGATGTCGGTGAGGCCAGTTCCCAACCTCCAAGGCGTGCCAAAATCAAAGAATAGGTCATAAATCATCTGTTATAGGTGGTCTAAAATTTTAAGATAGGCATGTTTGCCTTTTGAAAGATCTTCCGTGATTTTAAGAAGAGAAATATTCACAGATATGCAGCAAGCTCTTTTGGCCAAGGGATCCGACTTTAAATGTTCTTTGCTTCATTACTTTTACAAGCTTGATTACTATTGTAATAAATTCAAGGGTAAAAGACTGTTAACTACCCTCATGTTTCGTGGTTTTCAACATTTAGTACATCAAGTTTTTTTCGTC
Protein Sequence
- />MD05G1189400
MSIRRSAANQLAHMGVPAAMSSSLPVLPTSLEETHPNLPDSQQVSMERELMTRPVVHAGHLTSNSGVVGHIFSSSSGFSTDLHYSTHSPHEKQQKNSPFISQSPHSGFLQSTESCPYPKENSGSWCTDPLPGFLDFPVNNHIENSQIESSSCSGIMAADEFAKRHDWQEWADQLITDDDALTSNWNELLVDNVTDLEQKMKYQAPKPSPNFSVQQSQVHQQQPASSGEIIPAPSREIISVTAPSSANSATAKARMRWTPELHESFVEAVNQLGGSERATPKGVLKLMKVEHLTIYHVKSHLQKYRTARYRPESSEGASEKKLTPIEEMTSLDLKTGIEITEALRLQMEVQKRLHEQLEIQRNLQLRIEEQGKYLQMMFEKQCKSGIDTLNPSSSNLDDPSAQPSDATQVCLDKSEPESSKLGQGETQTDPVKANSTSSGGSQEPEGKQKAPETETVPQNPEPDVGEASSQPPRRAKIKE