Gene Details:

• Gene ID: LG7600774
• Gene Symbol: LsKN1
• Gene Name: knotted 1
• Genome: Lsat_Salinas_v11
• Species: Lactuca sativa

Functional Descriptions:

• We report the genetic cloning of a key regulator (LsKN1) of heading in lettuce, which is homologous to the knotted 1 (KN1) gene in maize.
• The LsKN1 gene is upregulated by the insertion of a CACTA-like transposon. Its enhanced expression suppressed the LsAS1 gene and consequently altered leaf polarity and led to a heading phenotype.
• Complementation and CRISPR/Cas9 knockout experiments confirmed the role of LsKN1 in heading. In heading lettuce, there is a CACTA-like transposon inserted into the first exon of LsKN1 (LsKN1▽).

Function-related keywords:

• leaf

Literature:

• Upregulation of a KN1 homolog by transposon insertion promotes leafy head development in lettuce.   DOI:  10.1073/pnas.2019698117 ;  PMID:  33288708

Related News:

• PNAS | 结球生菜为啥能结球？华中农大匡汉晖研究组首次克隆到控制生菜结球的基因

Gene Resources:

• NCBI ID: LOC111890976
• UniProt accessions:

Orthologs:

Sequences:

• CDS Sequence:
• Protein Sequence: