Gene Details:

  • Gene ID:
  • Gene Symbol: GhMKK4
  • Gene Name: mitogen-activated protein kinase kinase 2
  • Genome: TM1_NBI
  • Species: Gossypium hirsutum

Functional Descriptions:

  • The cotton MAPK kinase GhMPK20 negatively regulates resistance to Fusarium oxysporum by mediating the MKK4–MPK20–WRKY40 cascade.
  • VIGS of GhMKK4 and GhWRKY40 also enhanced F. oxysporum resistance in cotton, and the function of GhMKK4–GhMPK20 was shown to be essential for F. oxysporum-induced GhWRKY40 expression.
  • GhMKK4-silenced cotton displays enhanced resistance to F. oxysporum.
  • Overexpression of cotton GhMKK4 enhances disease susceptibility and affects abscisic acid, gibberellin and hydrogen peroxide signalling in transgenic Nicotiana benthamiana.
  • Our results indicate that the GhMKK4–GhMPK20–GhWRKY40 cascade in cotton plays an important role in the pathogenesis of F. oxysporum.

Literature:

Gene Resources:

Orthologs:

Sequences:

cDNA Sequence
CDS Sequence
Protein Sequence