Gene Details:

• Gene ID: GH_D09G0714
• Gene Symbol: GhADF6
• Gene Name: actin depolymerizing factor 6
• Genome: TM1_NBI
• Species: Gossypium hirsutum

Functional Descriptions:

• GhADF6-mediated actin reorganization is associated with defence against Verticillium dahliae infection in cotton.
• GhADF6 binds to actin filaments and possesses actin severing and depolymerizing activities in vitro and in vivo.
• By virus-induced gene silencing analysis, the down-regulation of GhADF6 expression rendered the cotton plants tolerant to V. dahliae infection.
• GhADF6 is an active actin depolymerizing and severing protein. The defence-related down-regulation of GhADF6 was found to augment the abundance of actin filaments and bundles, which was accompanied by enhanced disease tolerance against V. dahliae in cotton.
• Our findings demonstrate that the actin cytoskeleton was reorganized and F-actin abundance was increased on V. dahliae attack. Furthermore, regulating the expression of GhADF6 was identified to be crucial for this cellular process.

Function-related keywords:

• disease ,  tolerance ,  defence ,  actin-protein ,  cellular-activities ,  virus ,  protein

Literature:

• GhADF6-mediated actin reorganization is associated with defence against Verticillium dahliae infection in cotton.   DOI:  10.1111/mpp.13137 ;  PMID:  34515397

Related News:

Gene Resources:

• NCBI ID:
• UniProt accessions:

Sequences: