Information report for GHCU
Gene Details
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Functional Descriptions
- GHCU, a Molecular Chaperone, Regulates Leaf Curling by Modulating the Distribution of KNGH1 in Cotton.
- Knockout of GHCU or its homolog in cotton and tobacco using CRISPR results in abnormal leaf shape. It is further discovered that GHCU facilitates the transport of the HD protein KNOTTED1-like (KNGH1) from the adaxial to the abaxial domain.
- Loss of GHCU function restricts KNGH1 to the adaxial epidermal region, leading to lower auxin response levels in the adaxial boundary compared to the abaxial. This spatial asymmetry in auxin distribution produces the upward-curled leaf phenotype of the cu mutant.
- Overall, these findings suggest that GHCU plays a crucial role in the regulation of leaf flattening through facilitating cell-to-cell trafficking of KNGH1 and hence influencing the auxin response level.
- GHCU and its homologs are key in regulating cell enlargement and arrangement on the abaxial epidermis during leaf development.
Functional Keywords
- leaf , development , leaf-development , auxin , auxin-response , leaf-shape , auxin-transport , epidermis , leaf-flattening , protein
Literature and News
Sequences
cDNA Sequence
CDS Sequence
- >GH_A11G3380
ATGGCGTTCTCAATGCAACCTCATGGCATACAATCGATGCTTAAGGAAGGTCACAAGCATCTCTCAGGTCTCGATGAAGCTGTTTTGAAAAACATCGATGCTTGCAAGCAACTCTCAACAATCACCCGCACTTCCCTCGGCCCCGACGGTATGAATAAGATGGTTATTAATCATTTAGACAAGCTCTTTGTTACCAATGATGCTGCTACCATTGTCAATGAGCTTGAGGTTCAGCATCCGGCGGCAAAGATATTAGTTCTGGCGGGTAAGGCTCAGCAAGAGGAAATTGGTGATGGGGCTAATTTGACAATTTCTTTTGCCGGAGAGCTTCTCCAAAATGCTGAGGAGCTTGTTAGGACTGGCTTGCATCCGAGTGAGATAATCAGTGGATATACTAAAGCAATTACCAAGACACTTGAGATTTTGGAGGAGCTTGTAGAGAAAGGTTCTGAGACTATGGATGTACGGAATAAAGAGCAAGTTGTTAGTCGAATGAAAGCTGCTGTTGCTAGCAAACAATATGGGCTGGAAGATATATTGTCTTCCCATATAGCTGATGCTTGCATCCAAGTCTGCCCCAAGAACCCTGTGAACTTTGATGTTGATAATGTCCGTGTGTCAAAGCTTGTTGGAGGAGTTTTGCATAATTGCACAGTAATTAGGGGAATGGCTTTAAAAGGTGATGCTGTGGGAAGTATAAAACGTGTGGAGAAGGCGAAGGTGGCTGTGTTTGCTACTGGTGTTGATTCAACTGCTACTGAAACAAAAGGAACTGTTTTGATTCACTCTGCTGAGCAGCTGGAGAATTATGCAAAAACTGAAGAAGCTAAGGTTGAGGAGCTCATTAAAGCAGTTGCTGATTCTGGTGCCAAAGTTATCGTTAGTGGTGGAGCAGTCGGGGAAATGGCATTGCATTTCTGTGACCGTTACAAGCTAATGGTCTTGAAAATCAGCTCAAAGTTTGAACTACGACGCTTCTGCCGCACAACAGGCACTTCTGCTCTTCTGAAACTCAGCCAACCAAAGCCAGATGATTTGGGATTTGTTGATTCAATTTCAGTTGAGGAAATCGGTGGTTCTCGGGTCACTGTTGTGAGAAGTGAAGATGGGGGTAACAAGGTTGCCACTGTGGTTCTGCGAGGAAGTACTGATAGTATATTGGATGATCTTGAAAGAGCTGTTGATGATGGAGTCAATACATATAAGGCAATGTGCAGGGATAGTCGTATGGTACCTGGAGCTGCTGCTACAGAAATCGAGTTGGCGAGAAGACTGAAAGAGTTCTCCTTCAAGGAAACAGGATTGGATCAGTATGCCATTGCTAAGTTTGCTGAAAGTTTTGAATTGGTACCGAGAACCCTGGCAGAGAATGCTGGACTCAATCCAATGGATATTATTTCTAAGTTGTATGAAAAGCATGCATCTGGGAATGGTAAAGTGGGCATCGACTTGAGGGGAGACGACTCTGAGGACGGTGTTTGCAAGGATGTCTCAACCGTGAATGTTTGGGACCTTTATGTCACTAAGTTTTTGGCTCTCAAATATGCTGCAGAGGCTGCCTGCACTGTGTTGCGTGTAGATCAGATTATCATGGCGAAACCAGCTGGAGGTCCAGCGAGGAGAGATCAACCTGCAGGAATGGATGAGGACTAA
Protein Sequence
- >GH_A11G3380
ATGGCGTTCTCAATGCAACCTCATGGCATACAATCGATGCTTAAGGAAGGTCACAAGCATCTCTCAGGTCTCGATGAAGCTGTTTTGAAAAACATCGATGCTTGCAAGCAACTCTCAACAATCACCCGCACTTCCCTCGGCCCCGACGGTATGAATAAGATGGTTATTAATCATTTAGACAAGCTCTTTGTTACCAATGATGCTGCTACCATTGTCAATGAGCTTGAGGTTCAGCATCCGGCGGCAAAGATATTAGTTCTGGCGGGTAAGGCTCAGCAAGAGGAAATTGGTGATGGGGCTAATTTGACAATTTCTTTTGCCGGAGAGCTTCTCCAAAATGCTGAGGAGCTTGTTAGGACTGGCTTGCATCCGAGTGAGATAATCAGTGGATATACTAAAGCAATTACCAAGACACTTGAGATTTTGGAGGAGCTTGTAGAGAAAGGTTCTGAGACTATGGATGTACGGAATAAAGAGCAAGTTGTTAGTCGAATGAAAGCTGCTGTTGCTAGCAAACAATATGGGCTGGAAGATATATTGTCTTCCCATATAGCTGATGCTTGCATCCAAGTCTGCCCCAAGAACCCTGTGAACTTTGATGTTGATAATGTCCGTGTGTCAAAGCTTGTTGGAGGAGTTTTGCATAATTGCACAGTAATTAGGGGAATGGCTTTAAAAGGTGATGCTGTGGGAAGTATAAAACGTGTGGAGAAGGCGAAGGTGGCTGTGTTTGCTACTGGTGTTGATTCAACTGCTACTGAAACAAAAGGAACTGTTTTGATTCACTCTGCTGAGCAGCTGGAGAATTATGCAAAAACTGAAGAAGCTAAGGTTGAGGAGCTCATTAAAGCAGTTGCTGATTCTGGTGCCAAAGTTATCGTTAGTGGTGGAGCAGTCGGGGAAATGGCATTGCATTTCTGTGACCGTTACAAGCTAATGGTCTTGAAAATCAGCTCAAAGTTTGAACTACGACGCTTCTGCCGCACAACAGGCACTTCTGCTCTTCTGAAACTCAGCCAACCAAAGCCAGATGATTTGGGATTTGTTGATTCAATTTCAGTTGAGGAAATCGGTGGTTCTCGGGTCACTGTTGTGAGAAGTGAAGATGGGGGTAACAAGGTTGCCACTGTGGTTCTGCGAGGAAGTACTGATAGTATATTGGATGATCTTGAAAGAGCTGTTGATGATGGAGTCAATACATATAAGGCAATGTGCAGGGATAGTCGTATGGTACCTGGAGCTGCTGCTACAGAAATCGAGTTGGCGAGAAGACTGAAAGAGTTCTCCTTCAAGGAAACAGGATTGGATCAGTATGCCATTGCTAAGTTTGCTGAAAGTTTTGAATTGGTACCGAGAACCCTGGCAGAGAATGCTGGACTCAATCCAATGGATATTATTTCTAAGTTGTATGAAAAGCATGCATCTGGGAATGGTAAAGTGGGCATCGACTTGAGGGGAGACGACTCTGAGGACGGTGTTTGCAAGGATGTCTCAACCGTGAATGTTTGGGACCTTTATGTCACTAAGTTTTTGGCTCTCAAATATGCTGCAGAGGCTGCCTGCACTGTGTTGCGTGTAGATCAGATTATCATGGCGAAACCAGCTGGAGGTCCAGCGAGGAGAGATCAACCTGCAGGAATGGATGAGGACTAA