Gene Details:

  • Gene ID: Gh_A08G1390
  • Gene Symbol: GhRCD1
  • Gene Name:
  • Genome: TM1_NBI
  • Species: Gossypium hirsutum

Functional Descriptions:

  • GhRCD1 promotes Cd2+ tolerance by antagonistically interacting with GhbHLH12 and alleviating its repressive effect on GhMYB44 expression, thereby fostering GhMYB44 expression and improving Cd2+ tolerance.
  • Genetic knockout of GhRCD1 by CRISPR/Cas9 technology resulted in reduced Cd2+ tolerance in cotton seedlings, while GhRCD1 overexpression enhanced Cd2+ tolerance.
  • These findings provide critical insights into a novel GhRCD1–GhbHLH12–GhMYB44–GhHMA1 regulatory module responsible for Cd2+ tolerance in cotton.
  • GhRCD1 plays a vital role in Cd2+ tolerance, whereby genetic attenuation of GhRCD1 expression resulted in Cd2+ hypersensitivity, whereas the overexpression of GhRCD1 enhanced Cd2+ tolerance in cotton. GhRCD1 promotes Cd2+ tolerance by antagonistically interacting with GhbHLH12 and alleviating its repressive effect on GhMYB44 expression, thereby fostering GhMYB44 expression and improving Cd2+ tolerance.

Literature:

Gene Resources:

  • NCBI ID:
  • UniProt accessions:

Orthologs:

Sequences:

cDNA Sequence
CDS Sequence
  • >Gh_A08G1390
    ATGGAAGCACCGAACGCCATGGTATTGGATAGTAAGCCTTTGGTTCTACATGGCATGAAGAGGAAGCGGGAAACACAGCATACAACATATTTTCCTGGGGCCTCGCATCTGGTACCACTACAGTTGCCCAGCTTGTGTTTAGCTTTCCAGAAACATGACAAGCACAGGAGATTGGAGGATTGCGAAGGCAGAGTTGTGAGTTGTGGTTATACTTCAAAAAGATCTTTGTTACTTTGCTATTCAAATTTTAAGAAAACAGGCATTCCAAAGCGCATAATGTTCTATGAGAAAGGTGAATGGACTGATTTTCCCAATGATCTTATTGCCTCAATCAGGAAAGATCTCGTCACAAAGAAGCCGGCTATTGAGGTTGAGATAGACAGTCAATCTTTTGTGTTAGATTTCTTGCATATGTTTCGATTGGAGCTGAAAACTGGCATGAGACACCCCATTGCTTGGATTGATGAAGCAGGTGGCTGTTTCTTTCCTGAGATTTTTACTGGTGAGGATGAAGCATACCCGTGCTGCAAAGATGAATGTGCGAATGACCAAGAATTCATGTTTAGTGAATCTTATGCCCCTCGTGAGATCAAGCTACATCTTGAGATTGGCATTAATGGTGTTGAGCAGCCAAAGTTGGAATGTAGTGGGGAGTCGAGTTCTTTTGTGAGACATTTTCAAATTGCTCAGAAACCTGCCTCCAGTTATTCTGCTGCGGAAGCCGAGGATAATTGCAATAGGAGTGCCGATGGAAAACCCAATAAAGCTGTTGAGGATATTCAAGAGAAAAAGAAAAACTTAGTTCCAGAAAGCGAGTTTGTTGATGTACTGTTCAACGAGCCGTTGGAGTCTTCAACTGTTGAACAGATGTTTCTTATGGGTATGAACACTTGTGAAGGTGTGGATATTCTTGATATAAGACCCTGCTCCAGTACACAATATAGATTAGAGCGTTTCCAGAAGCAGGTCCAAATTATGAAGAAGTATCGGGGGACTGCAAATGTTCAACGTGCATGGCTTGCTTCCTCTAGAAAAGCATTGCCTACCATCATGATGCATGGGCTTGCAGACTGCCGTCTTTCTTCAATCCCAGACCTATATGCCGCTGGTGTTCATCTTGCTGCAGCAGAATTTACTAATGGCAGTGCAAAGTATTGTGATGTTGACGAAAATGGAGTACAGTACATGATATTATGTTGCGTAATAATGGGAAAGACGGAGCTTCTTTTCCCTGAAAGTGGACAATGTTTTCCTAGCAGTGAGGATGTTGATAGTGGAGTGGATGATCTTCATCATCCGAAGTATTATATTACCTGGAACATGAATATTAACACCCACATTTATCCAGAGTTTATTGTTAGTTTCAAACTCTCCTCGAATGCTAAAGTTTATGTGGTACCGACAGGGAATTCGGTTGGAAGTGAGGCTAGTCATGCTATTTCAGGTGTCACTGCATCTTCAAAAGGAGCCCAAGGTTGTTTACCAGCATCTGCTGGTGAATTGGGGAGTACTAAACACCAAAATTCAGATTCAGGGGGATCCCAAGAAAATGATCCTAGTCTGGGTTCAAACACTTCAAAGACCCCTAAATCCCCTTGGATGCCTTTCCCTATGTTGTTTGCTGCTATCTCAAATAAGATTCCTCGTATGGATATGGACCAAGTTGCTAATCATTATGAACTGTTCAGGGCAAAGAAGATAACTCGTGATGATTTTGTCAAAAAGTTGAGATTGATAGTTGGAGATAATTTGCTGAGGTCAACAATAACTTCACTACAAAGCAAGATACCATCGAGGCATGAATTAGAGGTGGCAAAACAGAACATGAAGGGTCCTGGAAGCCTTTGA
Protein Sequence
  • >Gh_A08G1390
    MEAPNAMVLDSKPLVLHGMKRKRETQHTTYFPGASHLVPLQLPSLCLAFQKHDKHRRLEDCEGRVVSCGYTSKRSLLLCYSNFKKTGIPKRIMFYEKGEWTDFPNDLIASIRKDLVTKKPAIEVEIDSQSFVLDFLHMFRLELKTGMRHPIAWIDEAGGCFFPEIFTGEDEAYPCCKDECANDQEFMFSESYAPREIKLHLEIGINGVEQPKLECSGESSSFVRHFQIAQKPASSYSAAEAEDNCNRSADGKPNKAVEDIQEKKKNLVPESEFVDVLFNEPLESSTVEQMFLMGMNTCEGVDILDIRPCSSTQYRLERFQKQVQIMKKYRGTANVQRAWLASSRKALPTIMMHGLADCRLSSIPDLYAAGVHLAAAEFTNGSAKYCDVDENGVQYMILCCVIMGKTELLFPESGQCFPSSEDVDSGVDDLHHPKYYITWNMNINTHIYPEFIVSFKLSSNAKVYVVPTGNSVGSEASHAISGVTASSKGAQGCLPASAGELGSTKHQNSDSGGSQENDPSLGSNTSKTPKSPWMPFPMLFAAISNKIPRMDMDQVANHYELFRAKKITRDDFVKKLRLIVGDNLLRSTITSLQSKIPSRHELEVAKQNMKGPGSL