Gene Details:

• Gene ID:
• Gene Symbol: Gh4CL3
• Gene Name: Cotton 4-coumarate-CoA ligase 3
• Genome: TM1_NBI
• Species: Gossypium hirsutum

Functional Descriptions:

• Cotton 4-coumarate-CoA ligase 3 (Gh4CL3) enhanced plant resistance to Verticillium dahliae by promoting jasmonic acid signaling-mediated vascular lignification and metabolic flux.
• These changes were coupled with a significant reduction in 4CL activity toward p-coumaric acid substrate, and it is likely that recombinant Gh4CL3 could specifically catalyze p-coumaric acid to form p-coumaroyl-coenzyme A.
• Overexpression of Gh4CL3 (OE4CL) showed increasing 4CL activity that augmented phenolic precursors, cinnamic, p-coumaric, and sinapic acids, channeling into lignin and flavonoid biosyntheses and enhanced resistance to V. dahliae.
• Our results propose that Gh4CL3 acts as a positive regulator for cotton resistance against V. dahliae by promoting JA signaling-mediated enhanced cell wall rigidity and metabolic flux.

Function-related keywords:

• resistance ,  ja ,  cell-wall ,  jasmonic ,  jasmonic-acid ,  flavonoid ,  lignin ,  ja-signaling

Literature:

• Cotton 4-coumarate-CoA ligase 3 enhanced plant resistance to Verticillium dahliae by promoting jasmonic acid signaling-mediated vascular lignification and metabolic flux.   DOI:  10.1111/tpj.16223 ;  PMID:  36994650

Related News:

Gene Resources:

• NCBI ID: MN897805
• UniProt accessions:

Orthologs:

Sequences: