Gene Details:

• Gene ID: Glyma.13g292300
• Gene Symbol: GmRIC1GmCLE1
• Gene Name: Rhizobia-Induced CLE1
• Genome: Wm82.a4.v1
• Species: Glycine max

Functional Descriptions:

• Here, we report that microRNA172c (miR172c) activates soybean (Glycine max) Rhizobia-Induced CLE1 (GmRIC1) and GmRIC2 by removing the transcriptional repression of these genes by Nodule Number Control 1 (NNC1), leading to the activation of the AON pathway.
• These results suggest that both GmRIC1 and GmRIC2 act downstream of NNC1 and that the miR172c/NNC1 module regulates nodule number in soybean via GmRIC1 and GmRIC2.
• NNC1 knockdown resulted in dramatically higher expression levels of GmRIC1 and GmRIC2 at 5 DAI, suggesting an NNC1 inhibits the expression of both genes during nodulation.
• Given this result, we speculated that GmNINa and NNC1 antagonistically regulate GmRIC1 and GmRIC2 expression by competing for cis-element binding during nodulation.
• The soybean (Glycine max) nodulation-suppressive CLE peptide, GmRIC1, functions interspecifically in common white bean (Phaseolus vulgaris), but not in a supernodulating line mutated in the receptor PvNARK.
• Homeologous over-expression of the nodulation-suppressive CLE peptide-encoding soybean gene, GmRIC1, abolished nodulation in wild-type bean, but had no discernible effect on PvNARK-mutant plants. This demonstrates that soybean GmRIC1 can function interspecifically in bean, acting in a PvNARK-dependent manner.
• The GmRIC1 and GmRIC2 genes initiated expression solely in the roots at approximately 3 days after inoculation (DAI) with Nod factor-producing rhizobia, corresponding to the time point of AON, and the expression was up-regulated by cytokinins.
• The results of this study suggest that GmRIC1 and GmRIC2 are good candidates for root-derived signal Q in AON signal transduction.

Function-related keywords:

• nodulation

Literature:

• A GmNINa-miR172c-NNC1 Regulatory Network Coordinates the Nodulation and Autoregulation of Nodulation Pathways in Soybean.   DOI:  10.1016/j.molp.2019.06.002 ;  PMID:  31201867
• The soybean (Glycine max) nodulation-suppressive CLE peptide, GmRIC1, functions interspecifically in common white bean (Phaseolus vulgaris), but not in a supernodulating line mutated in the receptor PvNARK.   DOI:  10.1016/j.molp.2019.06.002 ;  PMID:  25040127
• A GmNINa-miR172c-NNC1 Regulatory Network Coordinates the Nodulation and Autoregulation of Nodulation Pathways in Soybean.   DOI:  10.1093/pcp/pcr091 ;  PMID:  21757457
• Structure–function analysis of the GmRIC1 signal peptide and CLE domain required for nodulation control in soybean.   DOI:  10.1093/jxb/ert008 ;  PMID:  23386683

Related News:

• Molecular Plant | 华中农大李霞团队新成果！miR172可以整合分子网络以实现对结瘤每个环节的精细调整

Gene Resources:

• NCBI ID: 110599574
• UniProt accessions: A0A097I386

Sequences: