Gene Details:

• Gene ID: Glyma.17G112800
• Gene Symbol: GmKIX8-1
• Gene Name: KIX domain-containing protein
• Genome: Wm82.a4.v1
• Species: Glycine max

Functional Descriptions:

• Using forward genetic methods and CRISPR/Cas9 gene editing, we identified and characterized the role of GmKIX8-1 in the control of organ size in soybean.
• GmKIX8-1, involved in the control of cell proliferation and organ size through forward and reverse genetics using FN mutagenesis and CRISPR/Cas9 genome editing, respectively.
• GmKIX8-1 belongs to a family of KIX domain-containing proteins that negatively regulate cell proliferation in plants. Consistent with this predicted function, we found that loss-of-function GmKIX8-1 mutants showed a significant increase in the size of aerial plant organs, such as seeds and leaves.
• Lastly, molecular analysis of soybean germplasms harboring the qSw17-1 QTL for the big-seeded phenotype indicated that reduced expression of GmKIX8-1 is the genetic basis of the qSw17-1 phenotype.

Function-related keywords:

• cell-proliferation ,  organ-size

Literature:

• GmKIX8-1 regulates organ size in soybean and is the causative gene for the major seed weight QTL qSw17-1.   DOI:  10.1111/nph.16928 ;  PMID:  32939760

Related News:

Gene Resources:

• NCBI ID: 100806760
• UniProt accessions: K7ML46

Orthologs:

Sequences: