Gene Details:

• Gene ID: Glyma.16g090700
• Gene Symbol: GmRIN4b
• Gene Name: RPM1-interacting 4
• Genome: Wm82.a4.v1
• Species: Glycine max

Functional Descriptions:

• Using virus-induced gene silencing, we show that only GmRIN4a and b are required for Rpg1-b-mediated resistance. In planta binding assays show that GmRIN4a can associate with Rpg1-b indirectly via GmRIN4b.
• Pathogen-delivered AvrB induces the phosphorylation of GmRIN4b alone, and prevents interactions between GmRIN4b and Rpg1-b or GmRIN4a.
• Consistent with this result, a phosphomimic derivative of GmRIN4b (pm4b) fails to bind Rpg1-b and GmRIN4a. Conversely, a phosphodeficient derivative of GmRIN4b (pd4b) continues to bind the R protein and GmRIN4a, in the presence of AvrB.
• Our data suggest that the AvrB-induced phosphorylation of GmRIN4b, and the subsequent inhibition of interaction among GmRIN4b, GmRIN4a and Rpg1-b, might activate the R protein.

Function-related keywords:

• resistance ,  r-protein ,  pathogen ,  pathogen-resistance ,  virus ,  protein

Literature:

• GmRIN4 protein family members function nonredundantly in soybean race-specific resistance against Pseudomonas syringae.   DOI:  10.1111/nph.12093 ;  PMID:  23278373

Related News:

Gene Resources:

• NCBI ID: 100808509
• UniProt accessions: C6TH04

Orthologs:

Sequences: