Gene Details:
- Gene ID: Glyma.04G062500
- Gene Symbol: GmRR18a
- Gene Name: G. max RESPONSE REGULATOR 18a
- Genome: Wm82.a4.v1
- Species: Glycine max
Functional Descriptions:
- GmJAZ3 interacted with both G. max RESPONSE REGULATOR 18a (GmRR18a) and GmMYC2a to inhibit their transcriptional activation of cytokinin oxidase gene G. max CYTOKININ OXIDASE 3-4 (GmCKX3-4), which usually affects seed traits.
- The GmRR18a binds to the promoter of GmMYC2a and activates GmMYC2a gene expression.
- Taken together, our study reveals a novel molecular module GmJAZ3-GmRR18a/GmMYC2a-GmCKXs for seed size and weight control, providing promising targets during soybean molecular breeding for better seed traits.
Function-related keywords:
- seed , cytokinin , breeding , seed-weight , seed-size , transcriptional-regulator , cytokinin-response
Literature:
- GmJAZ3 interacts with GmRR18a and GmMYC2a to regulate seed traits in soybean. DOI: 10.1111/jipb.13494 ; PMID: 37066995
Related News:
Gene Resources:
Orthologs:
Sequences:
cDNA Sequence
- >Glyma.04G062500.2
GCTCCTTCTTTCCATTTATTGTTCTTTTCAATTATTCATTCACATTCCCCTCAGAAATTACTATTTCTTCCTCACAAAATAAACAATTTTTTGTTGTTTTCCTGTCTCCTCTGTTTCATAGCTTCAGGGTTTTGGTTTTCAGACCCACAAAACAGAGTTCAAGTGTGTAAAGATTGAAGAAGAAAATGACCGTAGAGAAGAAAAGGAATGATTCCGGCGACGAGTTCCCCGTCGGAATGCGTGTTCTTGCCGTCGATGATGACCCCACTTGCCTCTTGGTTCTGAAAACTCTCCTCCAAAGATGTCAATATCATGTAACCACGACTAATCAAGCAATAAAGGCGTTGGCTCTGTTGAGAGAACACAAAGACAAGTTTGACCTGGTAATCAGTGATGTACACATGCCAGACATGGATGGATTTAAGCTGCTTGAGCTAGTGGGACTTGAGATGGATCTTCCTGTCATAATGTTATCTGCAAATGGTGATACGAAGATGGTGATGAAGGGGATTTCTCATGGGGCCTGTGATTATCTGCTGAAACCTGTGAGAATGGAGGAGCTCAAGAACATTTGGCAGCATGTAATCAGGAGGAAGAAGTTTGACTCAAAGGAGAAGAACAAAACCAGCAACCTAGACAAACCTACTTCTAATAGTGGAAATGGACTAGGGTCATCAGGAACAGGAAATTCTGATCAAAATGAGAAGCTGACTAAGAAAAGGAAGGATCAAGATGAAGATGAAGATGAGGATCAGGAGAATGATCTTGACAATGAGGACCCATCAGCCCAGAAGAAGCCTCGGGTTGTTTGGTCTGTGGACCTGCACCGCAAGTTTGTTGCTGCTGTTAATCAGCTAGGCATTGACAAGGCTGTACCTAAAAAAATTCTTGATTTGATGAATGTTGAAAAGCTTACAAGGGAGAATGTGGCAAGCCATCTTCAGGCATTTTTCTATTCTTTTGTGCTTCAATTTAATGTAACATATACCTTTTCATTCACAGAATGTTTCTGCTTTATGAATTGGCTGCAGAAGTATAGGCTTTATCTGAAAAGAATTAGCTGTGTGGCTAACCAACAAGCCAATATGGTGGCGGCCTTAGGGGTTGCAGATCCATCCTATTTGAGAATGAGTTCGGTGAGCGGGGTTGGACATGTACAAACATTAAGTGGTTCCGGACAGCTTCATAACAATAATTTCAGATCCTTTCCACCTAGTGGGATAATTAATAGATTGAACACTCCTGCTGGTTTGAATGTGCATGGATTTCCTTCTGGAGTACTTCAATTGAGTCAATCACAAAATTTAAACAATGCCAATGATCATCATAAATTCCAGTCAGTCATTGTTCCTGTTAATCAGAATGGTGTTCAGGGAATGACAGTGTCTGTAGGGCTTGATCAACTGCAAAACAATAAGGTTGTTATGTCTGTTCAGAACCTGACCACTGTTTTTGATGCCAAAACAACTTTTCCTATCCCAAATAAACTCCCAGATCCAAGACCAAAAATAACCAACTCTGTCTCTCATACTTCAGATGTGCATTTCTCAAACAATGCCTTGATGTTGGAACCACGCCCTCAAGGCTCACAAGGGAGTGTAAGAATTGGAACATTATCTTCTTCAGTAGCCTCTCAACATTCGGAATTTTCTTTGTCTTTGCTGGATCAAGGTAGATATAGTGATAATTGGACAAGTGCTGTGCAGCCATCTGTGATCCAGACAAACTTTTTCCCTCCAAGTGAATGTTTTAGACAGACTAATATACCTCCTGCAGATAACATGGCTTCTGTACCCTTGCAAGGTGGGAATCTAAGTGGTCCATCCATCACTTCATTGTCCAGGCAATCCCATGATTCAATGACAGAAATGCACTCTGAAGGAATGACTTTTACTAACAGACCTGGGCATACAAGCAGTAATGTGCCATTTCAAGGGTGGGATGACCATAATCAGGATGCTACTCACCATTCAAATATTATGTCAATAAACTCACTGACTCCAGTCAATGGGGCTGCTGTTCAAGCTGGCCATGCAGCAACGAACTCGGTCTTACACAGAAACTTGGATTTTAATTATTGTGATCCCTTACAAATGAAGCATGAAGGGTTTGTGGAGTTAACTGATGAGACCTTATTGAAACAACATCAGGGGAATACCATGGACCAGCAAAAATCTCAAGAAAATCATTTCTCTAATAATCTTGGTTCACTGGAAGACTTGGTCAGTTCAATGATGAAATAGGAGAAAGATAAGATGAAACACTTGATGGAAACCTCATTTGCAATAATTACTCTGGTGGGTTATCTATGTGGTAGCAGGTTTGGCAGCACATACCAGCATATCATGCACATCCTCGTTGATGAATTTTGTAGTTTTCATTGTGTTTAACCACTTTTTTCTTCTCATAGTTACTATAGGCTTTAGCTTCTCCAGATTACTTTTTCCTGGGTAAAGTTTTCTAGGTTTGTTCCATTAAGGGCTTTCTAATTTTATACAAATGCTTTGTTGTCCTTGCCTTCAGGTCCAGCAATGCATTATGAAGTATCAATCACTTTGTTTAATCTACATAGATATGCTGGCCTGCAAATTGGACCTAGATCTTCTCTCACAGCCTCACTTGTAGTGAGGAGAGAGAGACAAAAGGTCCAGGTGGAACCCACTTGAACCTGTGTCTTTCTCACTCCTCGCTGCACTCTGTGTAGCAGATGGGGAGAGATCTGGGGTTGCAAATTTGTAAAATGTTAGGGATCCATAAACAAAGATTGTAGTGATTATGATGAATGACAATAAACATGGATGCCCCCTTTTATGCTT - >Glyma.04G062500.1
GCTCCTTCTTTCCATTTATTGTTCTTTTCAATTATTCATTCACATTCCCCTCAGAAATTACTATTTCTTCCTCACAAAATAAACAATTTTTTGTTGTTTTCCTGTCTCCTCTGTTTCATAGCTTCAGGGTTTTGGTTTTCAGACCCACAAAACAGAGTTCAAGTGTGTAAAGATTGAAGAAGAAAATGACCGTAGAGAAGAAAAGGAATGATTCCGGCGACGAGTTCCCCGTCGGAATGCGTGTTCTTGCCGTCGATGATGACCCCACTTGCCTCTTGGTTCTGAAAACTCTCCTCCAAAGATGTCAATATCATGTAACCACGACTAATCAAGCAATAAAGGCGTTGGCTCTGTTGAGAGAACACAAAGACAAGTTTGACCTGGTAATCAGTGATGTACACATGCCAGACATGGATGGATTTAAGCTGCTTGAGCTAGTGGGACTTGAGATGGATCTTCCTGTCATAATGTTATCTGCAAATGGTGATACGAAGATGGTGATGAAGGGGATTTCTCATGGGGCCTGTGATTATCTGCTGAAACCTGTGAGAATGGAGGAGCTCAAGAACATTTGGCAGCATGTAATCAGGAGGAAGAAGTTTGACTCAAAGGAGAAGAACAAAACCAGCAACCTAGACAAACCTACTTCTAATAGTGGAAATGGACTAGGGTCATCAGGAACAGGAAATTCTGATCAAAATGAGAAGCTGACTAAGAAAAGGAAGGATCAAGATGAAGATGAAGATGAGGATCAGGAGAATGATCTTGACAATGAGGACCCATCAGCCCAGAAGAAGCCTCGGGTTGTTTGGTCTGTGGACCTGCACCGCAAGTTTGTTGCTGCTGTTAATCAGCTAGGCATTGACAAGGCTGTACCTAAAAAAATTCTTGATTTGATGAATGTTGAAAAGCTTACAAGGGAGAATGTGGCAAGCCATCTTCAGGCATTTTTCTATTCTTTTGTGCTTCAATTTAATGTAACATATACCTTTTCATTCACAGAATGTTTCTGCTTTATGAATTGGCTGCAGAAGTATAGGCTTTATCTGAAAAGAATTAGCTGTGTGGCTAACCAACAAGCCAATATGGTGGCGGCCTTAGGGGTTGCAGATCCATCCTATTTGAGAATGAGTTCGGTGAGCGGGGTTGGACATGTACAAACATTAAGTGGTTCCGGACAGCTTCATAACAATAATTTCAGATCCTTTCCACCTAGTGGGATAATTAATAGATTGAACACTCCTGCTGGTTTGAATGTGCATGGATTTCCTTCTGGAGTACTTCAATTGAGTCAATCACAAAATTTAAACAATGCCAATGATCATCATAAATTCCAGTCAGTCATTGTTCCTGTTAATCAGAATGGTGTTCAGGGAATGACAGTGTCTGTAGGGCTTGATCAACTGCAAAACAATAAGGTTGTTATGTCTGTTCAGAACCTGACCACTGTTTTTGATGCCAAAACAACTTTTCCTATCCCAAATAAACTCCCAGATCCAAGACCAAAAATAACCAACTCTGTCTCTCATACTTCAGATGTGCATTTCTCAAACAATGCCTTGATGTTGGAACCACGCCCTCAAGGCTCACAAGGGAGTGTAAGAATTGGAACATTATCTTCTTCAGTAGCCTCTCAACATTCGGAATTTTCTTTGTCTTTGCTGGATCAAGGTAGATATAGTGATAATTGGACAAGTGCTGTGCAGCCATCTGTGATCCAGACAAACTTTTTCCCTCCAAGTGAATGTTTTAGACAGACTAATATACCTCCTGCAGATAACATGGCTTCTGTACCCTTGCAAGGTGGGAATCTAAGTGGTCCATCCATCACTTCATTGTCCAGGCAATCCCATGATTCAATGACAGAAATGCACTCTGAAGGAATGACTTTTACTAACAGACCTGGGCATACAAGCAGTAATGTGCCATTTCAAGGGTGGGATGACCATAATCAGGATGCTACTCACCATTCAAATATTATGTCAATAAACTCACTGACTCCAGTCAATGGGGCTGCTGTTCAAGCTGGCCATGCAGCAACGAACTCGGTCTTACACAGAAACTTGGATTTTAATTATTGTGATCCCTTACAAATGAAGCATGAAGGGTTTGTGGAGTTAACTGATGAGACCTTATTGAAACAACATCAGGGGAATACCATGGACCAGCAAAAATCTCAAGAAAATCATTTCTCTAATAATCTTGGTTCACTGGAAGACTTGGTCAGTTCAATGATGAAATAGGAGAAAGATAAGATGAAACACTTGATGGAAACCTCATTTGCAATAATTACTCTGGTGGGTTATCTATGTGGTAGCAGGTTTGGCAGCACATACCAGCATATCATGCACATCCTCGTTGATGAATTTTGTAGTTTTCATTGTGTTTAACCACTTTTTTCTTCTCATAGTTACTATAGGCTTTAGCTTCTCCAGATTACTTTTTCCTGGGTAAAGTTTTCTAGGTTTGTTCCATTAAGGGCTTTCTAATTTTATACAAATGCTTTGTTGTCCTTGCCTTCAGGTCCAGCAATGCATTATGAAGTATCAATCACTTTGTTTAATCTACATAGATATGCTGGCCTGCAAATTGGACCTAGATCTTCTCTCACAGCCTCACTTGTAGTGAGGAGAGAGAGACAAAAGGTCCAGGTGGAACCCACTTGAACCTGTGTCTTTCTCACTCCTCGCTGCACTCTGTGTAGCAGATGGGGAGAGATCTGGGGTTGCAAATTTGTAAAATGTTAGGGATCCATAAACAAAGATTGTAGTGATTATGATGAATGACAATAAACATGGATGCCCCCTTTTATGCTT
CDS Sequence
- >Glyma.04G062500.2
ATGACCGTAGAGAAGAAAAGGAATGATTCCGGCGACGAGTTCCCCGTCGGAATGCGTGTTCTTGCCGTCGATGATGACCCCACTTGCCTCTTGGTTCTGAAAACTCTCCTCCAAAGATGTCAATATCATGTAACCACGACTAATCAAGCAATAAAGGCGTTGGCTCTGTTGAGAGAACACAAAGACAAGTTTGACCTGGTAATCAGTGATGTACACATGCCAGACATGGATGGATTTAAGCTGCTTGAGCTAGTGGGACTTGAGATGGATCTTCCTGTCATAATGTTATCTGCAAATGGTGATACGAAGATGGTGATGAAGGGGATTTCTCATGGGGCCTGTGATTATCTGCTGAAACCTGTGAGAATGGAGGAGCTCAAGAACATTTGGCAGCATGTAATCAGGAGGAAGAAGTTTGACTCAAAGGAGAAGAACAAAACCAGCAACCTAGACAAACCTACTTCTAATAGTGGAAATGGACTAGGGTCATCAGGAACAGGAAATTCTGATCAAAATGAGAAGCTGACTAAGAAAAGGAAGGATCAAGATGAAGATGAAGATGAGGATCAGGAGAATGATCTTGACAATGAGGACCCATCAGCCCAGAAGAAGCCTCGGGTTGTTTGGTCTGTGGACCTGCACCGCAAGTTTGTTGCTGCTGTTAATCAGCTAGGCATTGACAAGGCTGTACCTAAAAAAATTCTTGATTTGATGAATGTTGAAAAGCTTACAAGGGAGAATGTGGCAAGCCATCTTCAGGCATTTTTCTATTCTTTTGTGCTTCAATTTAATGTAACATATACCTTTTCATTCACAGAATGTTTCTGCTTTATGAATTGGCTGCAGAAGTATAGGCTTTATCTGAAAAGAATTAGCTGTGTGGCTAACCAACAAGCCAATATGGTGGCGGCCTTAGGGGTTGCAGATCCATCCTATTTGAGAATGAGTTCGGTGAGCGGGGTTGGACATGTACAAACATTAAGTGGTTCCGGACAGCTTCATAACAATAATTTCAGATCCTTTCCACCTAGTGGGATAATTAATAGATTGAACACTCCTGCTGGTTTGAATGTGCATGGATTTCCTTCTGGAGTACTTCAATTGAGTCAATCACAAAATTTAAACAATGCCAATGATCATCATAAATTCCAGTCAGTCATTGTTCCTGTTAATCAGAATGGTGTTCAGGGAATGACAGTGTCTGTAGGGCTTGATCAACTGCAAAACAATAAGGTTGTTATGTCTGTTCAGAACCTGACCACTGTTTTTGATGCCAAAACAACTTTTCCTATCCCAAATAAACTCCCAGATCCAAGACCAAAAATAACCAACTCTGTCTCTCATACTTCAGATGTGCATTTCTCAAACAATGCCTTGATGTTGGAACCACGCCCTCAAGGCTCACAAGGGAGTGTAAGAATTGGAACATTATCTTCTTCAGTAGCCTCTCAACATTCGGAATTTTCTTTGTCTTTGCTGGATCAAGGTAGATATAGTGATAATTGGACAAGTGCTGTGCAGCCATCTGTGATCCAGACAAACTTTTTCCCTCCAAGTGAATGTTTTAGACAGACTAATATACCTCCTGCAGATAACATGGCTTCTGTACCCTTGCAAGGTGGGAATCTAAGTGGTCCATCCATCACTTCATTGTCCAGGCAATCCCATGATTCAATGACAGAAATGCACTCTGAAGGAATGACTTTTACTAACAGACCTGGGCATACAAGCAGTAATGTGCCATTTCAAGGGTGGGATGACCATAATCAGGATGCTACTCACCATTCAAATATTATGTCAATAAACTCACTGACTCCAGTCAATGGGGCTGCTGTTCAAGCTGGCCATGCAGCAACGAACTCGGTCTTACACAGAAACTTGGATTTTAATTATTGTGATCCCTTACAAATGAAGCATGAAGGGTTTGTGGAGTTAACTGATGAGACCTTATTGAAACAACATCAGGGGAATACCATGGACCAGCAAAAATCTCAAGAAAATCATTTCTCTAATAATCTTGGTTCACTGGAAGACTTGGTCAGTTCAATGATGAAATAG - >Glyma.04G062500.1
ATGACCGTAGAGAAGAAAAGGAATGATTCCGGCGACGAGTTCCCCGTCGGAATGCGTGTTCTTGCCGTCGATGATGACCCCACTTGCCTCTTGGTTCTGAAAACTCTCCTCCAAAGATGTCAATATCATGTAACCACGACTAATCAAGCAATAAAGGCGTTGGCTCTGTTGAGAGAACACAAAGACAAGTTTGACCTGGTAATCAGTGATGTACACATGCCAGACATGGATGGATTTAAGCTGCTTGAGCTAGTGGGACTTGAGATGGATCTTCCTGTCATAATGTTATCTGCAAATGGTGATACGAAGATGGTGATGAAGGGGATTTCTCATGGGGCCTGTGATTATCTGCTGAAACCTGTGAGAATGGAGGAGCTCAAGAACATTTGGCAGCATGTAATCAGGAGGAAGAAGTTTGACTCAAAGGAGAAGAACAAAACCAGCAACCTAGACAAACCTACTTCTAATAGTGGAAATGGACTAGGGTCATCAGGAACAGGAAATTCTGATCAAAATGAGAAGCTGACTAAGAAAAGGAAGGATCAAGATGAAGATGAAGATGAGGATCAGGAGAATGATCTTGACAATGAGGACCCATCAGCCCAGAAGAAGCCTCGGGTTGTTTGGTCTGTGGACCTGCACCGCAAGTTTGTTGCTGCTGTTAATCAGCTAGGCATTGACAAGGCTGTACCTAAAAAAATTCTTGATTTGATGAATGTTGAAAAGCTTACAAGGGAGAATGTGGCAAGCCATCTTCAGGCATTTTTCTATTCTTTTGTGCTTCAATTTAATGTAACATATACCTTTTCATTCACAGAATGTTTCTGCTTTATGAATTGGCTGCAGAAGTATAGGCTTTATCTGAAAAGAATTAGCTGTGTGGCTAACCAACAAGCCAATATGGTGGCGGCCTTAGGGGTTGCAGATCCATCCTATTTGAGAATGAGTTCGGTGAGCGGGGTTGGACATGTACAAACATTAAGTGGTTCCGGACAGCTTCATAACAATAATTTCAGATCCTTTCCACCTAGTGGGATAATTAATAGATTGAACACTCCTGCTGGTTTGAATGTGCATGGATTTCCTTCTGGAGTACTTCAATTGAGTCAATCACAAAATTTAAACAATGCCAATGATCATCATAAATTCCAGTCAGTCATTGTTCCTGTTAATCAGAATGGTGTTCAGGGAATGACAGTGTCTGTAGGGCTTGATCAACTGCAAAACAATAAGGTTGTTATGTCTGTTCAGAACCTGACCACTGTTTTTGATGCCAAAACAACTTTTCCTATCCCAAATAAACTCCCAGATCCAAGACCAAAAATAACCAACTCTGTCTCTCATACTTCAGATGTGCATTTCTCAAACAATGCCTTGATGTTGGAACCACGCCCTCAAGGCTCACAAGGGAGTGTAAGAATTGGAACATTATCTTCTTCAGTAGCCTCTCAACATTCGGAATTTTCTTTGTCTTTGCTGGATCAAGGTAGATATAGTGATAATTGGACAAGTGCTGTGCAGCCATCTGTGATCCAGACAAACTTTTTCCCTCCAAGTGAATGTTTTAGACAGACTAATATACCTCCTGCAGATAACATGGCTTCTGTACCCTTGCAAGGTGGGAATCTAAGTGGTCCATCCATCACTTCATTGTCCAGGCAATCCCATGATTCAATGACAGAAATGCACTCTGAAGGAATGACTTTTACTAACAGACCTGGGCATACAAGCAGTAATGTGCCATTTCAAGGGTGGGATGACCATAATCAGGATGCTACTCACCATTCAAATATTATGTCAATAAACTCACTGACTCCAGTCAATGGGGCTGCTGTTCAAGCTGGCCATGCAGCAACGAACTCGGTCTTACACAGAAACTTGGATTTTAATTATTGTGATCCCTTACAAATGAAGCATGAAGGGTTTGTGGAGTTAACTGATGAGACCTTATTGAAACAACATCAGGGGAATACCATGGACCAGCAAAAATCTCAAGAAAATCATTTCTCTAATAATCTTGGTTCACTGGAAGACTTGGTCAGTTCAATGATGAAATAG
Protein Sequence
- >Glyma.04G062500.2
MTVEKKRNDSGDEFPVGMRVLAVDDDPTCLLVLKTLLQRCQYHVTTTNQAIKALALLREHKDKFDLVISDVHMPDMDGFKLLELVGLEMDLPVIMLSANGDTKMVMKGISHGACDYLLKPVRMEELKNIWQHVIRRKKFDSKEKNKTSNLDKPTSNSGNGLGSSGTGNSDQNEKLTKKRKDQDEDEDEDQENDLDNEDPSAQKKPRVVWSVDLHRKFVAAVNQLGIDKAVPKKILDLMNVEKLTRENVASHLQAFFYSFVLQFNVTYTFSFTECFCFMNWLQKYRLYLKRISCVANQQANMVAALGVADPSYLRMSSVSGVGHVQTLSGSGQLHNNNFRSFPPSGIINRLNTPAGLNVHGFPSGVLQLSQSQNLNNANDHHKFQSVIVPVNQNGVQGMTVSVGLDQLQNNKVVMSVQNLTTVFDAKTTFPIPNKLPDPRPKITNSVSHTSDVHFSNNALMLEPRPQGSQGSVRIGTLSSSVASQHSEFSLSLLDQGRYSDNWTSAVQPSVIQTNFFPPSECFRQTNIPPADNMASVPLQGGNLSGPSITSLSRQSHDSMTEMHSEGMTFTNRPGHTSSNVPFQGWDDHNQDATHHSNIMSINSLTPVNGAAVQAGHAATNSVLHRNLDFNYCDPLQMKHEGFVELTDETLLKQHQGNTMDQQKSQENHFSNNLGSLEDLVSSMMK* - >Glyma.04G062500.1
MTVEKKRNDSGDEFPVGMRVLAVDDDPTCLLVLKTLLQRCQYHVTTTNQAIKALALLREHKDKFDLVISDVHMPDMDGFKLLELVGLEMDLPVIMLSANGDTKMVMKGISHGACDYLLKPVRMEELKNIWQHVIRRKKFDSKEKNKTSNLDKPTSNSGNGLGSSGTGNSDQNEKLTKKRKDQDEDEDEDQENDLDNEDPSAQKKPRVVWSVDLHRKFVAAVNQLGIDKAVPKKILDLMNVEKLTRENVASHLQAFFYSFVLQFNVTYTFSFTECFCFMNWLQKYRLYLKRISCVANQQANMVAALGVADPSYLRMSSVSGVGHVQTLSGSGQLHNNNFRSFPPSGIINRLNTPAGLNVHGFPSGVLQLSQSQNLNNANDHHKFQSVIVPVNQNGVQGMTVSVGLDQLQNNKVVMSVQNLTTVFDAKTTFPIPNKLPDPRPKITNSVSHTSDVHFSNNALMLEPRPQGSQGSVRIGTLSSSVASQHSEFSLSLLDQGRYSDNWTSAVQPSVIQTNFFPPSECFRQTNIPPADNMASVPLQGGNLSGPSITSLSRQSHDSMTEMHSEGMTFTNRPGHTSSNVPFQGWDDHNQDATHHSNIMSINSLTPVNGAAVQAGHAATNSVLHRNLDFNYCDPLQMKHEGFVELTDETLLKQHQGNTMDQQKSQENHFSNNLGSLEDLVSSMMK*