Gene Details:

• Gene ID:
• Gene Symbol: CsRab11A
• Gene Name: Rab GTPase 11
• Genome: Cucumis sativus ASM407v2
• Species: Cucumis sativus

Functional Descriptions:

• Cucumber (Cucumis sativus L.) translationally controlled tumor protein interacts with CsRab11A and promotes activation of target of rapamycin in response to Podosphaera xanthii.
• Transient transformation assays indicate that CsRab11A is involved in the defense against P. xanthii and promotes the activation of TOR signaling through CsTCTP.
• CsRab11A was found to interact with the N-terminal domain of TOR, facilitating the activation of TOR signaling, an effect that is enhanced by the overexpression of CsTCTP.
• These results suggest a sophisticated adaptive response mechanism in which upstream regulators, CsTCTP and CsRab11A, coordinate to modulate TOR function in response to P. xanthii, highlighting a novel aspect of plant–pathogen interactions.
• The extensive expression of CsRab11A in cucumber cells also served as additional evidence of the successful transient transformation assay in cucumber cotyledons.

Function-related keywords:

• defense-response ,  defense ,  pathogen ,  plant-defense-signaling ,  protein

Literature:

• Cucumber (Cucumis sativus L.) translationally controlled tumor protein interacts with CsRab11A and promotes activation of target of rapamycin in response to Podosphaera xanthii.   DOI:  10.1111/tpj.16766 ;  PMID:  38700955

Related News:

• 沈阳农业大学团队研究揭示黄瓜翻译控制肿瘤蛋白CsTCTP和CsRab11A互作调控TOR信号响应白粉病菌胁迫的分子机

Gene Resources:

• NCBI ID:
• UniProt accessions:

Orthologs:

Sequences: