Gene Details:

• Gene ID: CsaV3_6G021740
• Gene Symbol: CsMLO11
• Gene Name: Mildew Resistance Locus O 11
• Genome: Cucumis sativus ASM407v2
• Species: Cucumis sativus

Functional Descriptions:

• Knockout mutants of CsMLO8 and CsMLO11 generated by CRISPR/Cas9 both showed improved PM resistance in the stem, hypocotyl, and leaves, and the double mutant mlo8mlo11 displayed even stronger resistance.
• Mutations in CsMLO8 and CsMLO11 confer resistance of the relevant mutants to powdery mildew.
• These results suggest that the loss of function of CsMLO8 and CsMLO11 promoted the ROS burst, contributing to PM resistance.
• CsMLO8/CsMLO11 are required for full susceptibility of cucumber stem to powdery mildew and interact with CsCRK2 and CsRbohD.

Function-related keywords:

• stem ,  resistance ,  powdery-mildew ,  mildew-resistance ,  mildew ,  powdery-mildew-resistance

Literature:

• CsMLO8/11 are required for full susceptibility of cucumber stem to powdery mildew and interact with CsCRK2 and CsRbohD.   DOI:  10.1093/hr/uhad295 ;  PMID:  38404593

Related News:

Gene Resources:

• NCBI ID: 101212018
• UniProt accessions: A0A0A0KEQ4

Orthologs:

Sequences: