Gene Details:

Functional Descriptions:

  • CsMYB60 directly and indirectly activates structural genes to promote the biosynthesis of flavonols and proanthocyanidins in cucumber.
  • CsMYB60 activated CsFLS and CsLAR by binding to their promoters and directly or indirectly promoted the expression of CsbHLH42, CsMYC1, CsWD40, and CsTATA-box binding protein, resulting in the formation of complexes of these four proteins to increase the expression of Cs4CL and interact with CsTATA-box binding protein to regulate the expression of CsCHS, thereby regulating the biosynthesis of flavonols and PAs in cucumber.
  • Overexpression of CsMYB60 increases the accumulation of flavonols and PAs in different tissues, especially in spines.
  • CsMYB60 is the B gene that controls the biosynthesis of flavonols and PAs in cucumber.
  • CsMYB60 is a key regulator of flavonols and proanthocyanidans that determine the colour of fruit spines in cucumber.

Literature:

Gene Resources:

Orthologs:

Sequences:

cDNA Sequence
  • >Csa_4G003090
    CCGCTGACGTCGGAGATGGAGAGAGAGAGTGGTGGGTGTGGGGGATGTGTGGATGAGGTAAGGGAAGAGGAAATTATTAAGAAGACGCCAGAAGGACGACATGACGTTGGTGGGTCTGTTACAGTGAATTTGAATAATGATGTTTGGGAAGAAGACGAGATGTCGTTGGACTTGGATGAGTTGTTGACAAGCGTGGAAGACTACGAGGATGAAATTCATAAGTTCATCACAACTGGCACGTGCAAAAGCAACACCGATCATGTCTCCATTGCTCCGGCAGAGATGGAGGTGGGCGGTGAGTGTAGTTCCATAAGCAGCTCATCCTTGATGAGTCTTGACAGTCCATGGAACTGGGAAAGCTTCGCGGGGGACATAGAATGGGATGCCGGAGAAGATTTCGGAGGTGGGGTTGGGATTGCGGTTGCGGAATCGGAATCGGAGGCGGTGATTTCTTGGCTTTTGTCATGATGATA
CDS Sequence
  • >Csa_4G003090
    ATGGAGAGAGAGAGTGGTGGGTGTGGGGGATGTGTGGATGAGGTAAGGGAAGAGGAAATTATTAAGAAGACGCCAGAAGGACGACATGACGTTGGTGGGTCTGTTACAGTGAATTTGAATAATGATGTTTGGGAAGAAGACGAGATGTCGTTGGACTTGGATGAGTTGTTGACAAGCGTGGAAGACTACGAGGATGAAATTCATAAGTTCATCACAACTGGCACGTGCAAAAGCAACACCGATCATGTCTCCATTGCTCCGGCAGAGATGGAGGTGGGCGGTGAGTGTAGTTCCATAAGCAGCTCATCCTTGATGAGTCTTGACAGTCCATGGAACTGGGAAAGCTTCGCGGGGGACATAGAATGGGATGCCGGAGAAGATTTCGGAGGTGGGGTTGGGATTGCGGTTGCGGAATCGGAATCGGAGGCGGTGATTTCTTGGCTTTTGTCATGA
Protein Sequence
  • >Csa_4G003090
    MERESGGCGGCVDEVREEEIIKKTPEGRHDVGGSVTVNLNNDVWEEDEMSLDLDELLTSVEDYEDEIHKFITTGTCKSNTDHVSIAPAEMEVGGECSSISSSSLMSLDSPWNWESFAGDIEWDAGEDFGGGVGIAVAESESEAVISWLLS