Gene Details:

• Gene ID: Csa4M573860
• Gene Symbol: CsAAP2A
• Gene Name: Amino Acid Permease 2A
• Genome: Cucumis sativus ASM407v2
• Species: Cucumis sativus

Functional Descriptions:

• DM resistance in cucumber due to CsAAP2A mutations is caused by perturbing pathogen-induced amino acid loading of infected leaves.
• The decreased flow of amino acids towards infected leaves in CsAAP2A plants compared to the wild type might explain the resistant phenotype of the mutant, as this would limit the available nutrients for the pathogen and thereby its fitness.
• The finding that a loss-of-function mutation in the CsAAP2A gene provides (partial) resistance leads to the conclusion that CsAAP2A should be considered to be a susceptibility gene (S-gene) for downy mildew.
• Conclude that not only CsAAP2A but also SlAAP5A/SlAAP5B are susceptibility genes for oomycete pathogens.

Function-related keywords:

• resistance ,  pathogen ,  resistant ,  pathogen-resistance ,  mildew-resistance ,  mildew

Literature:

• The amino acid permease (AAP) genes CsAAP2A and SlAAP5A/B are required for oomycete susceptibility in cucumber and tomato.   DOI:  10.1111/mpp.13052 ;  PMID:  33934492

Related News:

Gene Resources:

• NCBI ID:
• UniProt accessions:

Orthologs:

Sequences: