Gene Details:

Functional Descriptions:

  • Impairing TOPLESS-WIP1 physical interaction leads to CRC expression, carpel determination, and consequently the expression of the stamina inhibitor, the aminocyclopropane-1-carboxylic acid synthase 7 (CmACS7), leading to female flower development.
  • We isolated a female-to-male sex transition mutant in melon and identified the causal gene as the carpel identity gene CRABS CLAW (CRC).
  • The master regulator of sex determination in cucurbits, the transcription factor WIP1 whose expression orchestrates male flower development, recruits the corepressor TOPLESS to the CRC promoter to suppress its expression through histone deacetylation.
  • CRC-control of floral meristem termination involves the transcription of YUCCA auxin biosynthetic genes and transcriptional repression of TORNADO2 (TRN2), a plasma membrane protein that modulates auxin homeostasis.

Literature:

Gene Resources:

  • NCBI ID:
  • UniProt accessions:

Orthologs:

Sequences:

  • CDS Sequence:
  • Protein Sequence: