Gene Details:

  • Gene ID:
  • Gene Symbol: LepR3
  • Gene Name: receptor-like protein 3
  • Genome:
  • Species: Brassica napus

Functional Descriptions:

  • The Brassica napus blackleg resistance gene LepR3 encodes a receptor-like protein triggered by the Leptosphaeria maculans effector AVRLM1.
  • LepR3, found in the Brassica napus cv ‘Surpass 400’, provides race-specific resistance to the fungal pathogen Leptosphaeria maculans, which was overcome after great devastation in Australia in 2004.
  • LepR3 was found to encode a receptor-like protein (RLP). We also demonstrated that avirulence towards LepR3 is conferred by AvrLm1, which is responsible for both the Rlm1 and LepR3-dependent resistance responses in B. napus.
  • LepR3 is the first functional B. napus disease resistance gene to be cloned. AvrLm1’s interaction with two independent resistance loci, Rlm1 and LepR3, highlights the need to consider redundant phenotypes in ‘gene-for-gene’ interactions and offers an explanation as to why LepR3 was overcome so rapidly in parts of Australia.

Literature:

Gene Resources:

Orthologs:

Sequences:

cDNA Sequence
CDS Sequence
Protein Sequence