Gene Details:
- Gene ID:
- Gene Symbol: AaORA
- Gene Name: octadecanoid-derivative responsive AP2-domain
- Genome:
- Species: Artemisia annua
Functional Descriptions:
- AaTCP15, a JA and ABA dual-responsive teosinte branched1/cycloidea/proliferating (TCP) TF, which is essential for JA and ABA-induced artemisinin biosynthesis by directly binding to and activating the promoters of DBR2 and ALDH1, two genes encoding enzymes for artemisinin biosynthesis.
- More importantly, AaTCP15 expression is activated by the multiple reported JA and ABA-responsive TFs that promote artemisinin biosynthesis.
- Our results establish a multilayer regulatory network of the AaGSW1-AaTCP15/AaORA module to regulate artemisinin biosynthesis through JA and ABA signalling, and provide an interesting avenue for future research exploring the special transcriptional regulation module of TCP genes associated with specialized metabolites in plants.
- AaORA, another positive regulator of artemisinin biosynthesis responds to JA and ABA, interacts with and enhances the transactivation activity of AaTCP15 and simultaneously activates AaTCP15 transcripts.
Function-related keywords:
Literature:
- and abscisic acid-activated AaGSW1-AaTCP15/AaORA transcriptional cascade promotes artemisinin biosynthesis in Artemisia annua. DOI: 10.1111/pbi.13561 ; PMID: 33539631
Related News:
Gene Resources:
Orthologs:
Sequences:
- CDS Sequence:
- Protein Sequence: