Gene Details:

• Gene ID: AT5G67580
• Gene Symbol: ATTBP3, ATTRB2, TBP3, TRB2
• Gene Name: TELOMERE REPEAT BINDING FACTOR 2, TELOMERE-BINDING PROTEIN 3
• Description: Homeodomain-like/winged-helix DNA-binding family protein;(source:Araport11)
• TAIR Accession: locus:2158611
• Genome: Araport11_genome_release
• Species: Arabidopsis thaliana

Transcripts:

• AT5G67580.1     AT5G67580.2

Plant Ontology Annotations:

• PO:0009005  — root — raíz (Spanish, exact), radices (exact, plural), radix (exact), 根 (Japanese, exact), aerial root (narrow), climbing root (narrow)
• PO:0009025  — vascular leaf — foliage leaf (exact), hoja vascular (Spanish, exact), leaf, vascular (exact), vascular leaves (exact, plural), 維管束のある葉, または維管束植物の葉 (Japanese, exact), crozier (related), macrophyll (related), megaphyll (related), ascidia (narrow), ascidium (narrow), fiddlehead (narrow), frond (narrow), needle-like leaf (narrow), pitcher (narrow), pitcher blade (narrow), pitcher-blade (narrow), scale-like leaf (narrow), sterile frond (narrow), trophophyll (narrow)
• PO:0009046  — flower — flor (Spanish, exact), 花 (Japanese, exact), floret (related), Asteraceae floret (narrow), basal flower (narrow), double flower (narrow), hermaphrodite flower (narrow), monoclinous flower (narrow), perfect flower (narrow)
• PO:0009047  — stem — caña (Spanish, exact), culm (exact), eje primario (Spanish, exact), primary axis (exact), primary stem (exact), tallo (Spanish, exact), tronco (Spanish, exact), 茎 (Japanese, exact), bole (narrow), cane (narrow), caudex (narrow), caudices (narrow), core (narrow), primocane (narrow), scape (narrow), stalk (narrow), trunk (narrow)
• PO:0000037  — shoot axis apex — ápice del epiblasto (epiblastema) (Spanish, exact), シュート頂、茎頂 (Japanese, exact)
• PO:0009009  — plant embryo — embrión (Spanish, exact), 植物胚 (Japanese, exact), germ (related), embryo (broad)
• PO:0009029  — stamen — estambre (Spanish, exact), 雄蕊 (Japanese, exact), Poaceae stamen (narrow), Zea stamen (narrow)
• PO:0009031  — sepal — sépalo (Spanish, exact), がく片 (Japanese, exact)
• PO:0025022  — collective leaf structure — estructura colectiva de hoja (Spanish, exact), leaf series (exact), 葉が集まった構造 (Japanese, exact), leaf whorl (narrow), rosette (narrow), cycle (broad), verticil (broad)
• PO:0025281  — pollen — polen (Spanish, exact), pollen grain (exact), 花粉 (Japanese, exact)

Gene Ontology:

• GO:0003691  — enables — double-stranded telomeric DNA binding
• GO:0005634  — located in — nucleus
• GO:0003700  — enables — DNA-binding transcription factor activity
• GO:0000976  — enables — transcription cis-regulatory region binding
• GO:0006334  — involved in — nucleosome assembly
• GO:0043170  — acts upstream of or within — macromolecule metabolic process
• GO:0000786  — part of — nucleosome
• GO:0042803  — enables — protein homodimerization activity
• GO:0005730  — located in — nucleolus
• GO:0005515  — enables — protein binding
• GO:0043047  — enables — single-stranded telomeric DNA binding
• GO:0000785  — part of — chromatin
• GO:0006996  — acts upstream of or within — organelle organization
• GO:0042162  — enables — telomeric DNA binding

Germplasm Phenotype:

• CS73435  — homozygous triple mutant shows strong morphological defects: seedlings very small when grown on solid media, and when transplanted onto soil, often fail to survive and are completely infertile

Function-related keywords:

• root ,  vascular leaf ,  flower ,  stem ,  shoot axis apex ,  plant embryo ,  stamen ,  sepal ,  flower ,  collective leaf structure ,  pollen

Literature:

• Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.   DOI:  10.1126/science.290.5499.2105 ;  PMID:  11118137
• The maize Single myb histone 1 gene, Smh1, belongs to a novel gene family and encodes a protein that binds telomere DNA repeats in vitro.   DOI:  10.1104/pp.103.026856 ;  PMID:  14576282
• Suppression of histone H1 genes in Arabidopsis results in heritable developmental defects and stochastic changes in DNA methylation.   DOI:  10.1534/genetics.104.031997 ;  PMID:  15489532
• DNA array analyses of Arabidopsis thaliana lacking a vacuolar Na+/H+ antiporter: impact of AtNHX1 on gene expression.   DOI:  10.1111/j.1365-313X.2004.02253.x ;  PMID:  15546358
• Interactions of putative telomere-binding proteins in Arabidopsis thaliana: identification of functional TRF2 homolog in plants.   DOI:  10.1016/j.febslet.2004.11.021 ;  PMID:  15589838
• The MYB transcription factor superfamily of Arabidopsis: expression analysis and phylogenetic comparison with the rice MYB family.   DOI:  10.1007/s11103-005-2910-y ;  PMID:  16463103
• Impact of AtNHX1, a vacuolar Na+/H+ antiporter, upon gene expression during and long-term salt stress in Arabidopsis thaliana.   DOI:  10.1186/1471-2229-7-18 ;  PMID:  17411438
• The pentratricopeptide repeat protein DELAYED GREENING1 is involved in the regulation of early chloroplast development and chloroplast gene expression in Arabidopsis.   DOI:  10.1104/pp.108.116194 ;  PMID:  18400937
• Global analysis of Arabidopsis gene expression uncovers a complex array of changes impacting pathogen response and cell cycle during geminivirus infection.   DOI:  10.1104/pp.108.121038 ;  PMID:  18650403
• Transcriptome analyses show changes in gene expression to accompany pollen germination and tube growth in Arabidopsis.   DOI:  10.1104/pp.108.126375 ;  PMID:  18775970
• AtTRB1, a telomeric DNA-binding protein from Arabidopsis, is concentrated in the nucleolus and shows highly dynamic association with chromatin.   DOI:  10.1111/j.1365-313X.2009.04094.x ;  PMID:  19947985
• Telomere repeat binding proteins are functional components of Arabidopsis telomeres and interact with telomerase.   DOI:  10.1111/tpj.12428 ;  PMID:  24397874
• Telomere-binding protein regulates the chromosome ends through the interaction with histone deacetylases in Arabidopsis thaliana.   DOI:  10.1093/nar/gkw067 ;  PMID:  26857545
• Phylogeny-Based Systematization of Arabidopsis Proteins with Histone H1 Globular Domain.   DOI:  10.1104/pp.16.00214 ;  PMID:  28298478
• The PEAT protein complexes are required for histone deacetylation and heterochromatin silencing.   DOI:  10.15252/embj.201798770 ;  PMID:  30104406
• Transcriptional regulation of nitrogen-associated metabolism and growth.   DOI:  10.1038/s41586-018-0656-3 ;  PMID:  30356219
• Arabidopsis TRB proteins function in H3K4me3 demethylation by recruiting JMJ14.   DOI:  10.1038/s41467-023-37263-9 ;  PMID:  36977663
• Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.   DOI:  10.1126/science.290.5499.2105 ;  PMID:  11118137
• Interactions of putative telomere-binding proteins in Arabidopsis thaliana: identification of functional TRF2 homolog in plants.   DOI:  10.1016/j.febslet.2004.11.021 ;  PMID:  15589838
• The MYB transcription factor superfamily of Arabidopsis: expression analysis and phylogenetic comparison with the rice MYB family.   DOI:  10.1007/s11103-005-2910-y ;  PMID:  16463103
• Mapping of interaction domains of putative telomere-binding proteins AtTRB1 and AtPOT1b from Arabidopsis thaliana.   DOI:  10.1016/j.febslet.2008.03.034 ;  PMID:  18387366
• Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.   DOI:  10.1126/science.290.5499.2105 ;  PMID:  11118137

Sequences: