Gene Details:

• Gene ID: AT5G40820
• Gene Symbol: ATATR, ATR, ATR-2, ATRAD3
• Gene Name: ARABIDOPSIS THALIANA ATAXIA TELANGIECTASIA-MUTATED AND RAD3-RELATED, Ataxia telangiectasia-mutated and RAD3-related, ATAXIA TELANGIECTASIA-MUTATED AND RAD3-RELATED 2
• Description: Ataxia telangiectasia-mutated and RAD3-like protein;(source:Araport11)
• TAIR Accession:
• Genome: Araport11_genome_release
• Species: Arabidopsis thaliana

Transcripts:

• AT5G40820.1     AT5G40820.4     AT5G40820.2     AT5G40820.3

Plant Ontology Annotations:

• PO:0000282  — trichome — tricoma (Spanish, exact), 毛茸、糸状体、毛 (Japanese, exact), seta (related), setae (related), capilli (narrow), capillus (narrow), cilia (narrow), cilium (narrow), glochid (narrow), glochidia (narrow), glochidium (narrow), hair (narrow), lepides (narrow), lepis (narrow), non-secretory trichome (narrow), scale (narrow), squama (narrow), squamae (narrow), squamella (narrow), squamellae (narrow), squamule (narrow), barb trichome (broad), bristle (broad)
• PO:0009005  — root — raíz (Spanish, exact), radices (exact, plural), radix (exact), 根 (Japanese, exact), aerial root (narrow), climbing root (narrow)
• PO:0000084  — plant sperm cell — célula espermática o esperma (Spanish, exact), male gamete (exact), microgamete (exact), 植物精子細胞 (Japanese, exact), sperm nucleus (related), sperm cell (broad)

Function-related keywords:

• trichome ,  root ,  plant sperm cell

Literature:

• ATR regulates a G2-phase cell-cycle checkpoint in Arabidopsis thaliana.   DOI:  10.1105/tpc.018903 ;  PMID:  15075397
• Aluminum-dependent root-growth inhibition in Arabidopsis results from AtATR-regulated cell-cycle arrest.   DOI:  10.1016/j.cub.2008.08.050 ;  PMID:  18835170
• Suppressor of gamma response 1 (SOG1) encodes a putative transcription factor governing multiple responses to DNA damage.   DOI:  10.1073/pnas.0810304106 ;  PMID:  19549833
• The Arabidopsis ATRIP ortholog is required for a programmed response to replication inhibitors.   DOI:  10.1111/j.1365-313X.2009.03975.x ;  PMID:  19619158
• Ribonucleotide reductase regulation in response to genotoxic stress in Arabidopsis.   DOI:  10.1104/pp.109.140053 ;  PMID:  19571309
• A link among DNA replication, recombination, and gene expression revealed by genetic and genomic analysis of TEBICHI gene of Arabidopsis thaliana.   DOI:  10.1371/journal.pgen.1000613 ;  PMID:  19696887
• A shared DNA-damage-response pathway for induction of stem-cell death by UVB and by gamma irradiation.   DOI:  10.1016/j.dnarep.2010.06.006 ;  PMID:  20634150
• Distinct roles of the ATR kinase and the Mre11-Rad50-Nbs1 complex in the maintenance of chromosomal stability in Arabidopsis.   DOI:  10.1105/tpc.110.078527 ;  PMID:  20876831
• Arabidopsis homologues of the histone chaperone ASF1 are crucial for chromatin replication and cell proliferation in plant development.   DOI:  10.1111/j.1365-313X.2011.04504.x ;  PMID:  21251110
• Programmed induction of endoreduplication by DNA double-strand breaks in Arabidopsis.   DOI:  10.1073/pnas.1103584108 ;  PMID:  21613568
• Breadth by depth: expanding our understanding of the repair of transposon-induced DNA double strand breaks via deep-sequencing.   DOI:  10.1016/j.dnarep.2011.07.011 ;  PMID:  21889425
• Arabidopsis ATM and ATR kinases prevent propagation of genome damage caused by telomere dysfunction.   DOI:  10.1105/tpc.111.092387 ;  PMID:  22158468
• ATR and MKP1 play distinct roles in response to UV-B stress in Arabidopsis.   DOI:  10.1111/tpj.12095 ;  PMID:  23237049
• The ATM-dependent DNA damage response acts as an upstream trigger for compensation in the fas1 mutation during Arabidopsis leaf development.   DOI:  10.1104/pp.113.216796 ;  PMID:  23616603
• Genetic analysis of the Replication Protein A large subunit family in Arabidopsis reveals unique and overlapping roles in DNA repair, meiosis and DNA replication.   DOI:  10.1093/nar/gkt1292 ;  PMID:  24335281
• Salicylic acid activates DNA damage responses to potentiate plant immunity.   DOI:  10.1016/j.molcel.2013.09.019 ;  PMID:  24207055
• Microbial pathogens trigger host DNA double-strand breaks whose abundance is reduced by plant defense responses.   DOI:  10.1371/journal.ppat.1004030 ;  PMID:  24699527
• Quantitative phosphoproteomics of the ataxia telangiectasia-mutated (ATM) and ataxia telangiectasia-mutated and rad3-related (ATR) dependent DNA damage response in Arabidopsis thaliana.   DOI:  10.1074/mcp.M114.040352 ;  PMID:  25561503
• Agrobacterium T-DNA integration into the plant genome can occur without the activity of key non-homologous end-joining proteins.   DOI:  10.1111/tpj.12779 ;  PMID:  25641249
• Aluminum-Dependent Terminal Differentiation of the Arabidopsis Root Tip Is Mediated through an ATR-, ALT2-, and SOG1-Regulated Transcriptional Response.   DOI:  10.1105/tpc.15.00172 ;  PMID:  26320227
• Arabidopsis PARG1 is the key factor promoting cell survival among the enzymes regulating post-translational poly(ADP-ribosyl)ation.   DOI:  10.1038/srep15892 ;  PMID:  26516022
• The Second Subunit of DNA Polymerase Delta Is Required for Genomic Stability and Epigenetic Regulation.   DOI:  10.1104/pp.15.01976 ;  PMID:  27208288
• Function of the Plant DNA Polymerase Epsilon in Replicative Stress Sensing, a Genetic Analysis.   DOI:  10.1104/pp.17.00031 ;  PMID:  28153919
• SUV2, which encodes an ATR-related cell cycle checkpoint and putative plant ATRIP, is required for aluminium-dependent root growth inhibition in Arabidopsis.   DOI:  10.1111/pce.12992 ;  PMID:  28556304
• Arabidopsis thaliana FANCD2 Promotes Meiotic Crossover Formation.   DOI:  10.1105/tpc.17.00745 ;  PMID:  29352063
• The Cell Cycle Checkpoint Regulator ATR Is Required for Internal Aluminum Toxicity-Mediated Root Growth Inhibition in Arabidopsis.   DOI:  10.3389/fpls.2018.00118 ;  PMID:  29491872
• Roles of MSH2 and MSH6 in cadmium-induced G2/M checkpoint arrest in Arabidopsis roots.   DOI:  10.1016/j.chemosphere.2018.03.017 ;  PMID:  29533809
• Histone chaperones play crucial roles in maintenance of stem cell niche during plant root development.   DOI:  10.1111/tpj.13933 ;  PMID:  29676825
• Ser-Gln sites of SOG1 are rapidly hyperphosphorylated in response to DNA double-strand breaks.   DOI:  10.1080/15592324.2018.1477904 ;  PMID:  29939818
• Arabidopsis E2Fc is required for the DNA damage response under UV-B radiation epistatically over the microRNA396 and independently of E2Fe.   DOI:  10.1111/tpj.14158 ;  PMID:  30427087
• role of SUPPRESSOR OF GAMMA RESPONSE 1: An overview.   DOI:  10.1016/j.mrfmmm.2020.111689 ;  PMID:  32004947
• The ATR-WEE1 kinase module inhibits the MAC complex to regulate replication stress response.   DOI:  10.1093/nar/gkaa1082 ;  PMID:  33450002
• SOG1 transcription factor promotes the onset of endoreduplication under salinity stress in Arabidopsis.   DOI:  10.1038/s41598-021-91293-1 ;  PMID:  34079040
• Detection of Genes in Arabidopsis thaliana L. Responding to DNA Damage from Radiation and Other Stressors in Spaceflight.   DOI:  10.3390/genes12060938 ;  PMID:  34205326
• G2/M-checkpoint activation in fasciata1 rescues an aberrant S-phase checkpoint but causes genome instability.   DOI:  10.1093/plphys/kiab201 ;  PMID:  34618100
• Ultraviolet-B Radiation Represses Primary Root Elongation by Inhibiting Cell Proliferation in the Meristematic Zone of Arabidopsis Seedlings.   DOI:  10.3389/fpls.2022.829336 ;  PMID:  35401611
• Identification and Characterization of SOG1 (Suppressor of Gamma Response 1) Homologues in Plants Using Data Mining Resources and Gene Expression Profiling.   DOI:  10.3390/genes13040667 ;  PMID:  35456473
• The nucleotide metabolome of germinating Arabidopsis thaliana seeds reveals a central role for thymidine phosphorylation in chloroplast development.   DOI:  10.1093/plcell/koac207 ;  PMID:  35861422
• The ATR-WEE1 kinase module promotes SUPPRESSOR OF GAMMA RESPONSE 1 translation to activate replication stress responses.   DOI:  10.1093/plcell/koad126 ;  PMID:  37159556
• Cell-specific protein profiling in Arabidopsis thaliana trichomes: identification of trichome-located proteins involved in sulfur metabolism and detoxification.   DOI:  10.1016/j.phytochem.2004.03.026 ;  PMID:  15276459
• ATR and ATM play both distinct and additive roles in response to ionizing radiation.   DOI:  10.1111/j.1365-313X.2006.02931.x ;  PMID:  17227549
• Arabidopsis WEE1 kinase controls cell cycle arrest in response to activation of the DNA integrity checkpoint.   DOI:  10.1105/tpc.106.045047 ;  PMID:  17209125
• The DNA replication checkpoint aids survival of plants deficient in the novel replisome factor ETG1.   DOI:  10.1038/emboj.2008.107 ;  PMID:  18528439

Sequences: