Gene Details:

• Gene ID: AT5G37020
• Gene Symbol: ARF8, ATARF8
• Gene Name: auxin response factor 8
• Description: auxin response factor 8;(source:Araport11)
• TAIR Accession: locus:2152642
• Genome: Araport11_genome_release
• Species: Arabidopsis thaliana

Transcripts:

• AT5G37020.1     AT5G37020.2     AT5G37020.3

Plant Ontology Annotations:

• PO:0009005  — root — raíz (Spanish, exact), radices (exact, plural), radix (exact), 根 (Japanese, exact), aerial root (narrow), climbing root (narrow)
• PO:0009046  — flower — flor (Spanish, exact), 花 (Japanese, exact), floret (related), Asteraceae floret (narrow), basal flower (narrow), double flower (narrow), hermaphrodite flower (narrow), monoclinous flower (narrow), perfect flower (narrow)
• PO:0020003  — plant ovule — óvulo vegetal (Spanish, exact), 胚珠 (Japanese, exact), Poaceae ovule (narrow), Zea ovule (narrow)
• PO:0025074  — embryo sac — saco embrionario (Spanish, exact), 胚嚢 (Japanese, exact)
• PO:0000018  — ovule primordium — portion of ovule primordium tissue (exact), primordio de óvulo (Spanish, exact), 胚珠原基（可視的） (Japanese, exact)
• PO:0000052  — petiole vascular system — sistema vascular del pecíolo (Spanish, exact), 葉柄維管系 (Japanese, exact)
• PO:0009029  — stamen — estambre (Spanish, exact), 雄蕊 (Japanese, exact), Poaceae stamen (narrow), Zea stamen (narrow)
• PO:0009030  — carpel — carpelo (Spanish, exact), 心皮 (Japanese, exact), Poaceae carpel (narrow), Zea carpel (narrow), pistil (broad)
• PO:0009032  — petal — pétalo (Spanish, exact), 花弁 (Japanese, exact)
• PO:0020001  — plant ovary placenta — placenta de ovario (Spanish, exact), 子房胎座 (Japanese, exact), Poaceae ovary placenta (narrow), Zea ovary placenta (narrow)
• PO:0020006  — funicle — funículo (Spanish, exact), funiculi (exact, plural), 珠柄 (Japanese, exact), funiculus (related), Poaceae funicle (narrow), Zea funicle (narrow)
• PO:0020102  — portion of transmitting tissue — porción del tejido de transmisión (Spanish, exact), 伝達組織の一部 (Japanese, exact), transmitting tract (related), Poaceae transmitting tissue (narrow)
• PO:0025166  — papilla cell — célula papilosa (Spanish, exact), 乳頭細胞 (Japanese, exact)
• PO:0000084  — plant sperm cell — célula espermática o esperma (Spanish, exact), male gamete (exact), microgamete (exact), 植物精子細胞 (Japanese, exact), sperm nucleus (related), sperm cell (broad)

Gene Ontology:

• GO:0010154  — acts upstream of negative effect — fruit development
• GO:0003700  — enables — DNA-binding transcription factor activity
• GO:0006355  — involved in — regulation of DNA-templated transcription
• GO:0000976  — enables — transcription cis-regulatory region binding
• GO:0009733  — acts upstream of or within — response to auxin
• GO:0005515  — enables — protein binding
• GO:0005634  — located in — nucleus
• GO:0006355  — acts upstream of or within — regulation of DNA-templated transcription
• GO:0009908  — acts upstream of or within — flower development

Function-related keywords:

• root ,  flower ,  flower ,  plant ovule ,  embryo sac ,  ovule primordium ,  petiole vascular system ,  stamen ,  carpel ,  petal ,  plant ovary placenta ,  funicle ,  portion of transmitting tissue ,  papilla cell ,  plant sperm cell

Literature:

• Dimerization and DNA binding of auxin response factors.   DOI:  10.1046/j.1365-313x.1999.00538.x ;  PMID:  10476078
• Activation and repression of transcription by auxin-response factors.   DOI:  10.1073/pnas.96.10.5844 ;  PMID:  10318972
• Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.   DOI:  10.1126/science.290.5499.2105 ;  PMID:  11118137
• AUXIN RESPONSE FACTOR7 restores the expression of auxin-responsive genes in mutant Arabidopsis leaf mesophyll protoplasts.   DOI:  10.1105/tpc.105.031096 ;  PMID:  15923351
• Auxin response factors ARF6 and ARF8 promote jasmonic acid production and flower maturation.   DOI:  10.1242/dev.01955 ;  PMID:  16107481
• Plant fertility defects induced by the enhanced expression of microRNA167.   DOI:  10.1038/sj.cr.7310057 ;  PMID:  16699541
• AUXIN RESPONSE FACTOR8 is a negative regulator of fruit initiation in Arabidopsis.   DOI:  10.1105/tpc.105.037192 ;  PMID:  16829592
• Arabidopsis microRNA167 controls patterns of ARF6 and ARF8 expression, and regulates both female and male reproduction.   DOI:  10.1242/dev.02602 ;  PMID:  17021043
• Global analysis of Arabidopsis gene expression uncovers a complex array of changes impacting pathogen response and cell cycle during geminivirus infection.   DOI:  10.1104/pp.108.121038 ;  PMID:  18650403
• Phenotypic plasticity of adventitious rooting in Arabidopsis is controlled by complex regulation of AUXIN RESPONSE FACTOR transcripts and microRNA abundance.   DOI:  10.1105/tpc.108.064758 ;  PMID:  19820192
• Arabidopsis auxin response factor6 and 8 regulate jasmonic acid biosynthesis and floral organ development via repression of class 1 KNOX genes.   DOI:  10.1093/pcp/pcp176 ;  PMID:  20007966
• Auxins reverse plant male sterility caused by high temperatures.   DOI:  10.1073/pnas.1000869107 ;  PMID:  20421476
• A transcriptional feedback loop modulating signaling crosstalks between auxin and brassinosteroid in Arabidopsis.   DOI:  10.1007/s10059-010-0055-6 ;  PMID:  20396969
• AUXIN RESPONSE FACTOR8 regulates Arabidopsis petal growth by interacting with the bHLH transcription factor BIGPETALp.   DOI:  10.1105/tpc.110.081653 ;  PMID:  21421811
• Misregulation of AUXIN RESPONSE FACTOR 8 underlies the developmental abnormalities caused by three distinct viral silencing suppressors in Arabidopsis.   DOI:  10.1371/journal.ppat.1002035 ;  PMID:  21589905
• HALF FILLED promotes reproductive tract development and fertilization efficiency in Arabidopsis thaliana.   DOI:  10.1242/dev.067793 ;  PMID:  21693516
• A regulatory network for coordinated flower maturation.   DOI:  10.1371/journal.pgen.1002506 ;  PMID:  22346763
• Auxin controls Arabidopsis adventitious root initiation by regulating jasmonic acid homeostasis.   DOI:  10.1105/tpc.112.099119 ;  PMID:  22730403
• A gain-of-function mutation in IAA8 alters Arabidopsis floral organ development by change of jasmonic acid level.   DOI:  10.1007/s11103-013-0039-y ;  PMID:  23483289
• Down-regulation of AUXIN RESPONSE FACTORS 6 and 8 by microRNA 167 leads to floral development defects and female sterility in tomato.   DOI:  10.1093/jxb/eru141 ;  PMID:  24723401
• Promoter-based integration in plant defense regulation.   DOI:  10.1104/pp.114.248716 ;  PMID:  25352272
• An Arabidopsis gene regulatory network for secondary cell wall synthesis.   DOI:  10.1038/nature14099 ;  PMID:  25533953
• The phytoplasmal virulence factor TENGU causes plant sterility by downregulating of the jasmonic acid and auxin pathways.   DOI:  10.1038/srep07399 ;  PMID:  25492247
• Protein-protein interaction and gene co-expression maps of ARFs and Aux/IAAs in Arabidopsis.   DOI:  10.3389/fpls.2014.00744 ;  PMID:  25566309
• Overexpression of AtGRDP2, a novel glycine-rich domain protein, accelerates plant growth and improves stress tolerance.   DOI:  10.3389/fpls.2014.00782 ;  PMID:  25653657
• Coevolution Pattern and Functional Conservation or Divergence of miR167s and their targets across Diverse Plant Species.   DOI:  10.1038/srep14611 ;  PMID:  26459056
• Expression of Concern: Misregulation of AUXIN RESPONSE FACTOR 8 Underlies the Developmental Abnormalities Caused by Three Distinct Viral Silencing Suppressors in Arabidopsis.   DOI:  10.1371/journal.ppat.1005234 ;  PMID:  26451730
• Establishment of Expression in the SHORTROOT-SCARECROW Transcriptional Cascade through Opposing Activities of Both Activators and Repressors.   DOI:  10.1016/j.devcel.2016.09.031 ;  PMID:  27923776
• Expression profiling of AUXIN RESPONSE FACTOR genes during somatic embryogenesis induction in Arabidopsis.   DOI:  10.1007/s00299-017-2114-3 ;  PMID:  28255787
• Ectopic expression of UGT84A2 delayed flowering by indole-3-butyric acid-mediated transcriptional repression of ARF6 and ARF8 genes in Arabidopsis.   DOI:  10.1007/s00299-017-2225-x ;  PMID:  29027578
• Involvement of PACLOBUTRAZOL RESISTANCE6/KIDARI, an Atypical bHLH Transcription Factor, in Auxin Responses in Arabidopsis.   DOI:  10.3389/fpls.2017.01813 ;  PMID:  29114256
• ARF2-ARF4 and ARF5 are Essential for Female and Male Gametophyte Development in Arabidopsis.   DOI:  10.1093/pcp/pcx174 ;  PMID:  29145642
• A Newly Identified Flower-Specific Splice Variant of AUXIN RESPONSE FACTOR8 Regulates Stamen Elongation and Endothecium Lignification in Arabidopsis.   DOI:  10.1105/tpc.17.00840 ;  PMID:  29514943
• Comparative adventitious root development in pre-etiolated and flooded Arabidopsis hypocotyls exposed to different auxins.   DOI:  10.1016/j.plaphy.2018.03.022 ;  PMID:  29604522
• LBD18 uses a dual mode of a positive feedback loop to regulate ARF expression and transcriptional activity in Arabidopsis.   DOI:  10.1111/tpj.13945 ;  PMID:  29681137
• Jasmonate promotes auxin-induced adventitious rooting in dark-grown Arabidopsis thaliana seedlings and stem thin cell layers by a cross-talk with ethylene signalling and a modulation of xylogenesis.   DOI:  10.1186/s12870-018-1392-4 ;  PMID:  30189848
• Arabidopsis ANAC092 regulates auxin-mediated root development by binding to the ARF8 and PIN4 promoters.   DOI:  10.1111/jipb.12735 ;  PMID:  30415491
• LBD16 and LBD18 acting downstream of ARF7 and ARF19 are involved in adventitious root formation in Arabidopsis.   DOI:  10.1186/s12870-019-1659-4 ;  PMID:  30704405
• An Essential Role for miRNA167 in Maternal Control of Embryonic and Seed Development.   DOI:  10.1104/pp.19.00127 ;  PMID:  30867333
• miR167 limits anther growth to potentiate anther dehiscence.   DOI:  10.1242/dev.174375 ;  PMID:  31262724
• A Molecular Framework for the Control of Adventitious Rooting by TIR1/AFB2-Aux/IAA-Dependent Auxin Signaling in Arabidopsis.   DOI:  10.1016/j.molp.2019.09.001 ;  PMID:  31520787
• Photoexcited CRY1 and phyB interact directly with ARF6 and ARF8 to regulate their DNA-binding activity and auxin-induced hypocotyl elongation in Arabidopsis.   DOI:  10.1111/nph.16194 ;  PMID:  31514232
• Light controls stamen elongation via cryptochromes, phytochromes and COP1 through HY5 and HYH.   DOI:  10.1111/tpj.14736 ;  PMID:  32142184
• HUA ENHANCER1 Mediates Ovule Development.   DOI:  10.3389/fpls.2020.00397 ;  PMID:  32351522
• Overexpression of Arabidopsis microRNA167 induces salicylic acid-dependent defense against Pseudomonas syringae through the regulation of its targets ARF6 and ARF8.   DOI:  10.1002/pld3.270 ;  PMID:  33005858
• Auxin and gibberellin signaling cross-talk promotes hypocotyl xylem expansion and cambium homeostasis.   DOI:  10.1093/jxb/erab089 ;  PMID:  33619529
• Identification of transcription factors controlling cell wall invertase gene expression for reproductive development via bioinformatic and transgenic analyses.   DOI:  10.1111/tpj.15218 ;  PMID:  33650173
• A crosstalk between auxin and brassinosteroid regulates leaf shape by modulating growth anisotropy.   DOI:  10.1016/j.molp.2021.03.011 ;  PMID:  33722761
• The full-length Auxin Response Factor 8 isoform ARF8.1 controls pollen cell wall formation and directly regulates TDF1, AMS and MS188 expression.   DOI:  10.1111/tpj.16089 ;  PMID:  36597651
• Activation and repression of transcription by auxin-response factors.   DOI:  10.1073/pnas.96.10.5844 ;  PMID:  10318972
• Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.   DOI:  10.1126/science.290.5499.2105 ;  PMID:  11118137
• Cell-specific nitrogen responses mediate developmental plasticity.   DOI:  10.1073/pnas.0709559105 ;  PMID:  18180456

Sequences: