Gene Details:

• Gene ID: AT5G35620
• Gene Symbol: EIF(ISO)4E, EIF4E2, eIFiso4E, LSP, LSP1
• Gene Name: EUKARYOTIC INITIATION FACTOR (ISO)4E, EUKARYOTIC TRANSLATION INITATION FACTOR 4E2, eukaryotic translation Initiation Factor isoform 4E, LOSS OF SUSCEPTIBILITY TO POTYVIRUS 1
• Description: Eukaryotic initiation factor 4E protein;(source:Araport11)
• TAIR Accession: locus:2165892
• Genome: Araport11_genome_release
• Species: Arabidopsis thaliana

Transcripts:

• AT5G35620.1     AT5G35620.2     AT5G35620.3

Plant Ontology Annotations:

• PO:0009005  — root — raíz (Spanish, exact), radices (exact, plural), radix (exact), 根 (Japanese, exact), aerial root (narrow), climbing root (narrow)
• PO:0000084  — plant sperm cell — célula espermática o esperma (Spanish, exact), male gamete (exact), microgamete (exact), 植物精子細胞 (Japanese, exact), sperm nucleus (related), sperm cell (broad)

Gene Ontology:

• GO:0005634  — located in — nucleus
• GO:0005515  — enables — protein binding
• GO:0005845  — part of — mRNA cap binding complex
• GO:0006413  — acts upstream of or within — translational initiation
• GO:0005737  — located in — cytoplasm
• GO:0050687  — involved in — negative regulation of defense response to virus
• GO:0009536  — located in — plastid
• GO:0009615  — acts upstream of or within — response to virus
• GO:0000340  — enables — RNA 7-methylguanosine cap binding
• GO:0003743  — enables — translation initiation factor activity
• GO:0016281  — part of — eukaryotic translation initiation factor 4F complex

Function-related keywords:

• root ,  plant sperm cell

Literature:

• The plant translational apparatus.   DOI:  10.1007/BF00039380 ;  PMID:  8980477
• High-throughput protein localization in Arabidopsis using Agrobacterium-mediated transient expression of GFP-ORF fusions.   DOI:  10.1111/j.1365-313X.2004.02281.x ;  PMID:  15610358
• Coordinated and selective recruitment of eIF4E and eIF4G factors for potyvirus infection in Arabidopsis thaliana.   DOI:  10.1016/j.febslet.2007.02.007 ;  PMID:  17316629
• Transcriptome analyses show changes in gene expression to accompany pollen germination and tube growth in Arabidopsis.   DOI:  10.1104/pp.108.126375 ;  PMID:  18775970
• Translation initiation factor (iso) 4E interacts with BTF3, the beta subunit of the nascent polypeptide-associated complex.   DOI:  10.1016/j.gene.2004.11.030 ;  PMID:  15716105
• Deletion of the eIFiso4G subunit of the Arabidopsis eIFiso4F translation initiation complex impairs health and viability.   DOI:  10.1007/s11103-010-9670-z ;  PMID:  20694742
• Translation initiation factor AteIF(iso)4E is involved in selective mRNA translation in Arabidopsis thaliana seedlings.   DOI:  10.1371/journal.pone.0031606 ;  PMID:  22363683
• The TPLATE adaptor complex drives clathrin-mediated endocytosis in plants.   DOI:  10.1016/j.cell.2014.01.039 ;  PMID:  24529374
• Five eIF4E isoforms from Arabidopsis thaliana are characterized by distinct features of cap analogs binding.   DOI:  10.1016/j.bbrc.2014.11.032 ;  PMID:  25446076
• Discovery and characterization of conserved binding of eIF4E 1 (CBE1), a eukaryotic translation initiation factor 4E-binding plant protein.   DOI:  10.1074/jbc.RA118.003945 ;  PMID:  30213859
• Arabidopsis translation initiation factors eIFiso4G1/2 link repression of mRNA cap-binding complex eIFiso4F assembly with RNA-binding protein SOAR1-mediated ABA signaling.   DOI:  10.1111/nph.15880 ;  PMID:  31050354
• eIFiso4G Augments the Synthesis of Specific Plant Proteins Involved in Normal Chloroplast Function.   DOI:  10.1104/pp.19.00557 ;  PMID:  31308150
• Viral silencing suppressors and cellular proteins partner with plant RRP6-like exoribonucleases.   DOI:  10.1007/s11262-020-01775-z ;  PMID:  32519287

Sequences: