Gene Details:

• Gene ID: AT5G26920
• Gene Symbol: CBP60G
• Gene Name: Cam-binding protein 60-like G
• Description: Cam-binding protein 60-like G;(source:Araport11)
• TAIR Accession:
• Genome: Araport11_genome_release
• Species: Arabidopsis thaliana

Transcripts:

• AT5G26920.1     AT5G26920.2     AT5G26920.3

Plant Ontology Annotations:

• PO:0009005  — root — raíz (Spanish, exact), radices (exact, plural), radix (exact), 根 (Japanese, exact), aerial root (narrow), climbing root (narrow)

Germplasm Phenotype:

• CS72190  — Plants are less susceptible to infection by Pseudomonas syringae pv. maculicola ES4326. Reduced pattern-triggered immunity (PTI). Mock-inoculated plants show elevated salicylic acid levels.
• CS72191  — Plants are more susceptible to bacterial infection. Salicylic acid (SA) levels and SA-dependent gene expression are dramatically reduced.
• CS72193  — Plants are more susceptible to infection by Pseudomonas syringae pv. maculicola ES4326. Increased pattern-triggered immunity (PTI). Mock-inoculated plants show elevated salicylic acid (SA) levels; reduced SA levels in inoculated plants.
• CS860820  — Plants are more susceptible to infection by Pseudomonas syringae pv. maculicola ES4326. Expression profile of plants challenged with P. syringae pv tomato DC3000 hrcC is altered. Salicylic acid levels are lower compared to wild-type following treatment with flg22 peptide, challenge with P. syringae pv tomato DC3000 hrcC, or infection with P. syringae pv. maculicola ES4326 (only at an early time point).
• CS860821  — Plants are more susceptible to infection by Pseudomonas syringae pv. maculicola ES4326. Salicylic acid levels are lower compared to wild-type following treatment with flg22 peptide or challenge with P. syringae pv. tomato DC3000 hrcC.
• GK-075G12  — cbp60g-2 plants are more susceptible to infection by Pseudomonas syringae pv. maculicola ES4326. Salicylic acid levels are lower in cbp60g-2 than in wild-type following treatment with flg22 peptide or challenge with P. syringae pv. tomato DC3000 hrcC.
• SALK_023199C  — cbp60g-1 plants are more susceptible to infection by Pseudomonas syringae pv. maculicola ES4326. The expression profile of plants challenged with P. syringae pv tomato DC3000 hrcC is altered. Salicylic acid levels are lower in cbp60g-1 than in wild-type following treatment with flg22 peptide, challenge with P. syringae pv tomato DC3000 hrcC, or infection with P. syringae pv. maculicola ES4326 (only at an early time point). CBP60g binds calmodulin, and calmodulin-binding is necessary for complementation of cbp60g-1 pathogen growth and salicylate defects. These phenotypes were interpreted as indicating a defect in activation of salicylate synthesis during a MAMP/PAMP (microbe/pathogen- associated molecular pattern) response.

Function-related keywords:

• root

Literature:

• Genes encoding calmodulin-binding proteins in the Arabidopsis genome.   DOI:  10.1074/jbc.M111626200 ;  PMID:  11782485
• Inactivation of the chloroplast ATP synthase gamma subunit results in high non-photochemical fluorescence quenching and altered nuclear gene expression in Arabidopsis thaliana.   DOI:  10.1074/jbc.M308435200 ;  PMID:  14576160
• Binding of arabinogalactan proteins by Yariv phenylglycoside triggers wound-like responses in Arabidopsis cell cultures.   DOI:  10.1104/pp.104.039370 ;  PMID:  15235117
• Cesium toxicity in Arabidopsis.   DOI:  10.1104/pp.104.046672 ;  PMID:  15489280
• 12-oxo-phytodienoic acid triggers expression of a distinct set of genes and plays a role in wound-induced gene expression in Arabidopsis.   DOI:  10.1104/pp.105.067058 ;  PMID:  16258017
• A high-performance, small-scale microarray for expression profiling of many samples in Arabidopsis-pathogen studies.   DOI:  10.1111/j.1365-313X.2006.02972.x ;  PMID:  17181774
• Global analysis of Arabidopsis gene expression uncovers a complex array of changes impacting pathogen response and cell cycle during geminivirus infection.   DOI:  10.1104/pp.108.121038 ;  PMID:  18650403
• Arabidopsis CaM binding protein CBP60g contributes to MAMP-induced SA accumulation and is involved in disease resistance against Pseudomonas syringae.   DOI:  10.1371/journal.ppat.1000301 ;  PMID:  19214217
• The AP2/ERF transcription factor AtERF73/HRE1 modulates ethylene responses during hypoxia in Arabidopsis.   DOI:  10.1104/pp.111.172486 ;  PMID:  21398256
• Control of salicylic acid synthesis and systemic acquired resistance by two members of a plant-specific family of transcription factors.   DOI:  10.1073/pnas.1005225107 ;  PMID:  20921422
• CBP60g and SARD1 play partially redundant critical roles in salicylic acid signaling.   DOI:  10.1111/j.1365-313X.2011.04655.x ;  PMID:  21615571
• Pseudomonas fluorescens induces strain-dependent and strain-independent host plant responses in defense networks, primary metabolism, photosynthesis, and fitness.   DOI:  10.1094/MPMI-09-11-0253 ;  PMID:  22375709
• Calmodulin-binding protein CBP60g is a positive regulator of both disease resistance and drought tolerance in Arabidopsis.   DOI:  10.1007/s00299-012-1247-7 ;  PMID:  22466450
• Co-expression analysis identifies putative targets for CBP60g and SARD1 regulation.   DOI:  10.1186/1471-2229-12-216 ;  PMID:  23153277
• The CALMODULIN-BINDING PROTEIN60 family includes both negative and positive regulators of plant immunity.   DOI:  10.1104/pp.113.227108 ;  PMID:  24134885
• Spatial and temporal regulation of biosynthesis of the plant immune signal salicylic acid.   DOI:  10.1073/pnas.1511182112 ;  PMID:  26139525
• Phylogeny of Plant CAMTAs and Role of AtCAMTAs in Nonhost Resistance to Xanthomonas oryzae pv. oryzae.   DOI:  10.3389/fpls.2016.00177 ;  PMID:  26973658
• Two Redundant Receptor-Like Cytoplasmic Kinases Function Downstream of Pattern Recognition Receptors to Regulate Activation of SA Biosynthesis.   DOI:  10.1104/pp.15.01954 ;  PMID:  27208222
• Calmodulin-binding protein CBP60g functions as a negative regulator in Arabidopsis anthocyanin accumulation.   DOI:  10.1371/journal.pone.0173129 ;  PMID:  28253311
• TGACG-BINDING FACTOR 1 (TGA1) and TGA4 regulate salicylic acid and pipecolic acid biosynthesis by modulating the expression of SYSTEMIC ACQUIRED RESISTANCE DEFICIENT 1 (SARD1) and CALMODULIN-BINDING PROTEIN 60g (CBP60g).   DOI:  10.1111/nph.14780 ;  PMID:  28898429
• The plant-specific transcription factors CBP60g and SARD1 are targeted by a Verticillium secretory protein VdSCP41 to modulate immunity.   DOI:  10.7554/eLife.34902 ;  PMID:  29757140
• Pathogens Suppress Host Transcription Factors for Rampant Proliferation.   DOI:  10.1016/j.tplants.2018.08.010 ;  PMID:  30241734
• Different Modes of Negative Regulation of Plant Immunity by Calmodulin-Related Genes.   DOI:  10.1104/pp.17.01209 ;  PMID:  29449432
• Calcium-signaling proteins mediate the plant transcriptomic response during a well-established Xanthomonas campestris pv. campestris infection.   DOI:  10.1038/s41438-019-0186-7 ;  PMID:  31645958
• N-3-oxo-octanoyl-homoserine lactone-mediated priming of resistance to Pseudomonas syringae requires the salicylic acid signaling pathway in Arabidopsis thaliana.   DOI:  10.1186/s12870-019-2228-6 ;  PMID:  31992205
• Arabidopsis CBP60b is a central transcriptional activator of immunity.   DOI:  10.1093/plphys/kiab164 ;  PMID:  33848345
• WRKY54 and WRKY70 positively regulate SARD1 and CBP60g expression in plant immunity.   DOI:  10.1080/15592324.2021.1932142 ;  PMID:  34120569
• HISTONE DEACETYLASE 6 suppresses salicylic acid biosynthesis to repress autoimmunity.   DOI:  10.1093/plphys/kiab408 ;  PMID:  34618093
• Pathogen-driven coevolution across the CBP60 plant immune regulator subfamilies confers resilience on the regulator module.   DOI:  10.1111/nph.17769 ;  PMID:  34610150
• Arabidopsis CALMODULIN-BINDING PROTEIN 60b plays dual roles in plant immunity.   DOI:  10.1016/j.xplc.2021.100213 ;  PMID:  34778745
• Drought attenuates plant defence against bacterial pathogens by suppressing the expression of CBP60g/SARD1 during combined stress.   DOI:  10.1111/pce.14275 ;  PMID:  35102557
• Increasing the resilience of plant immunity to a warming climate.   DOI:  10.1038/s41586-022-04902-y ;  PMID:  35768511
• TOUCH 3 and CALMODULIN 1/4/6 cooperate with calcium-dependent protein kinases to trigger calcium-dependent activation of CAM-BINDING PROTEIN 60-LIKE G and regulate fungal resistance in plants.   DOI:  10.1093/plcell/koac209 ;  PMID:  35863056
• AIG2A and AIG2B limit the activation of salicylic acid-regulated defenses by tryptophan-derived secondary metabolism in Arabidopsis.   DOI:  10.1093/plcell/koac255 ;  PMID:  35972413
• Genes encoding calmodulin-binding proteins in the Arabidopsis genome.   DOI:  10.1074/jbc.M111626200 ;  PMID:  11782485

Sequences: