Gene Details:

• Gene ID: AT5G26680
• Gene Symbol: FEN1, SAV6
• Gene Name: Flap Endonuclease I, SHADE AVOIDANCE 6
• Description:
• TAIR Accession: locus:2146824
• Genome: Araport11_genome_release
• Species: Arabidopsis thaliana

Transcripts:

Plant Ontology Annotations:

• PO:0009005  — root — raíz (Spanish, exact), radices (exact, plural), radix (exact), 根 (Japanese, exact), aerial root (narrow), climbing root (narrow)
• PO:0000084  — plant sperm cell — célula espermática o esperma (Spanish, exact), male gamete (exact), microgamete (exact), 植物精子細胞 (Japanese, exact), sperm nucleus (related), sperm cell (broad)

Gene Ontology:

• GO:0005634  — located in — nucleus
• GO:0008409  — enables — 5-3 exonuclease activity
• GO:0048256  — enables — flap endonuclease activity
• GO:0017108  — enables — 5-flap endonuclease activity GO:0017108 8073 F catalytic activity IBA none PANTHER:PTN000118612|PomBase:SPAC3G6.06c|TAIR:locus:2099463|FB:FBgn0263831|UniProtKB:P39748|SGD:S000005559|SGD:S000001596|TAIR:locus:2025447|UniProtKB:Q17RS7 Communication:501741973 2023-06-07 AT5G26680 gene:1005713743 AT5G26680.1 enables flap endonuclease activity GO:0048256 17229 F nuclease activity IDA Enzyme assays Publication:501767634|PMID:26721386 TAIR 2016-01-21 AT5G26680 locus:2146824 AT5G26680 acts upstream of or within response to UV GO:0009411 4960 P response to light stimulus IGI Functional complementation in heterologous system SGD_ID:S000001596 Publication:501767634|PMID:26721386 TAIR 2016-02-08 AT5G26680 locus:2146824 AT5G26680 enables 5-flap endonuclease activity

Germplasm Phenotype:

• sav6/sav6  — Short roots and hypocotyl. Reduced root apical meristem. Short root due to reduced number of cells and cell elongation defects.Increased sensitivity to UV induced DNA damage.

Function-related keywords:

• root ,  plant sperm cell

Literature:

• Genome-wide analysis of the core DNA replication machinery in the higher plants Arabidopsis and rice.   DOI:  10.1104/pp.107.101105 ;  PMID:  17556508
• A predicted interactome for Arabidopsis.   DOI:  10.1104/pp.107.103465 ;  PMID:  17675552
• A crystallization and preliminary X-ray diffraction study of the Arabidopsis thaliana proliferating cell nuclear antigen (PCNA2) alone and in a complex with a PIP-box peptide from Flap endonuclease 1.   DOI:  10.18388/abp.2020_2896 ;  PMID:  32188236

Sequences: