Gene Details:

• Gene ID: AT5G24470
• Gene Symbol: APRR5, PRR5
• Gene Name: pseudo-response regulator 5, pseudo-response regulator 5
• Description: two-component response regulator-like protein;(source:Araport11)
• TAIR Accession: locus:2184007
• Genome: Araport11_genome_release
• Species: Arabidopsis thaliana

Transcripts:

• AT5G24470.1

Plant Ontology Annotations:

• PO:0009005  — root — raíz (Spanish, exact), radices (exact, plural), radix (exact), 根 (Japanese, exact), aerial root (narrow), climbing root (narrow)

Gene Ontology:

• GO:0009640  — acts upstream of or within — photomorphogenesis
• GO:0006355  — acts upstream of or within — regulation of DNA-templated transcription
• GO:0007623  — acts upstream of or within — circadian rhythm
• GO:0005634  — located in — nucleus
• GO:0000156  — enables — phosphorelay response regulator activity
• GO:0051170  — acts upstream of or within — import into nucleus
• GO:0045892  — acts upstream of or within — negative regulation of DNA-templated transcription
• GO:0009736  — involved in — cytokinin-activated signaling pathway
• GO:0003677  — enables — DNA binding
• GO:0010114  — acts upstream of or within — response to red light
• GO:0010218  — acts upstream of or within — response to far red light
• GO:0005515  — enables — protein binding
• GO:0005622  — located in — intracellular anatomical structure

Germplasm Phenotype:

• CS9384  — Has reciprocal period defects for multiple circadian rhythms, consistent with subtly altered expression patterns of the Circadian clock-associated gene (CCA1) and the Timing of CAB Expression gene (TOC1); rising and/or falling phases of transcripts are slightly advanced compared to Col; shorter circadian period relative to Col (1.0-2.4 hours ); alters the period of CCA1 expression in blue light by 2 hours, affects the period of CCR2 expression in red and blue light to a lesser extent, but had no effect on the period of CCA1 expression in red light or of CCR2 expression in darkness; seedlings show mild long-hypocotyl phenotype when grown under constant red or blue light at a range of fluence rates; circadian effects are complementary, light-dependent and inconsistent with the serial activation of PRR genes.
• CS9386  — Pseudo-response regulator double mutant; leaf movements remain robustly rhythmic with a period indistinguishable from the wild type Col.

Function-related keywords:

• root

Literature:

• Light response of the circadian waves of the APRR1/TOC1 quintet: when does the quintet start singing rhythmically in Arabidopsis?   DOI:  10.1093/pcp/pce036 ;  PMID:  11266585
• Two-component circuitry in Arabidopsis cytokinin signal transduction.   DOI:  10.1038/35096500 ;  PMID:  11574878
• Two-component signal transduction pathways in Arabidopsis.   DOI:  10.1104/pp.005504 ;  PMID:  12068096
• Aberrant expression of the Arabidopsis circadian-regulated APRR5 gene belonging to the APRR1/TOC1 quintet results in early flowering and hypersensitiveness to light in early photomorphogenesis.   DOI:  10.1093/pcp/pcf166 ;  PMID:  12461138
• Circadian waves of expression of the APRR1/TOC1 family of pseudo-response regulators in Arabidopsis thaliana: insight into the plant circadian clock.   DOI:  10.1093/pcp/pcd043 ;  PMID:  11100772
• Response regulator homologues have complementary, light-dependent functions in the Arabidopsis circadian clock.   DOI:  10.1007/s00425-003-1106-4 ;  PMID:  12955513
• Identification of ASK and clock-associated proteins as molecular partners of LKP2 (LOV kelch protein 2) in Arabidopsis.   DOI:  10.1093/jxb/erh226 ;  PMID:  15310821
• The Arabidopsis pseudo-response regulators, PRR5 and PRR7, coordinately play essential roles for circadian clock function.   DOI:  10.1093/pcp/pci061 ;  PMID:  15695441
• PSEUDO-RESPONSE REGULATOR 7 and 9 are partially redundant genes essential for the temperature responsiveness of the Arabidopsis circadian clock.   DOI:  10.1105/tpc.104.029504 ;  PMID:  15705949
• PSEUDO-RESPONSE REGULATORS, PRR9, PRR7 and PRR5, together play essential roles close to the circadian clock of Arabidopsis thaliana.   DOI:  10.1093/pcp/pci086 ;  PMID:  15767265
• Pseudo-Response Regulators (PRRs) or True Oscillator Components (TOCs).   DOI:  10.1093/pcp/pci087 ;  PMID:  15767264
• phyA dominates in transduction of red-light signals to rapidly responding genes at the initiation of Arabidopsis seedling de-etiolation.   DOI:  10.1111/j.1365-313X.2006.02914.x ;  PMID:  17076805
• Characterization of circadian-associated pseudo-response regulators: II. The function of PRR5 and its molecular dissection in Arabidopsis thaliana.   DOI:  10.1271/bbb.60584 ;  PMID:  17284847
• Characterization of the rice circadian clock-associated pseudo-response regulators in Arabidopsis thaliana.   DOI:  10.1271/bbb.70048 ;  PMID:  17420570
• Genetic linkages between circadian clock-associated components and phytochrome-dependent red light signal transduction in Arabidopsis thaliana.   DOI:  10.1093/pcp/pcm063 ;  PMID:  17519251
• Arabidopsis clock-associated pseudo-response regulators PRR9, PRR7 and PRR5 coordinately and positively regulate flowering time through the canonical CONSTANS-dependent photoperiodic pathway.   DOI:  10.1093/pcp/pcm056 ;  PMID:  17504813
• Insight into missing genetic links between two evening-expressed pseudo-response regulator genes TOC1 and PRR5 in the circadian clock-controlled circuitry in Arabidopsis thaliana.   DOI:  10.1093/pcp/pcm178 ;  PMID:  18178585
• Involvement of Arabidopsis clock-associated pseudo-response regulators in diurnal oscillations of gene expression in the presence of environmental time cues.   DOI:  10.1093/pcp/pcn165 ;  PMID:  19015137
• Transcript profiling of an Arabidopsis PSEUDO RESPONSE REGULATOR arrhythmic triple mutant reveals a role for the circadian clock in cold stress response.   DOI:  10.1093/pcp/pcp004 ;  PMID:  19131357
• PRR5 (PSEUDO-RESPONSE REGULATOR 5) plays antagonistic roles to CCA1 (CIRCADIAN CLOCK-ASSOCIATED 1) in Arabidopsis thaliana.   DOI:  10.1271/bbb.69.426 ;  PMID:  15725674
• Characterization of genetic links between two clock-associated genes, GI and PRR5 in the current clock model of Arabidopsis thaliana.   DOI:  10.1271/bbb.80321 ;  PMID:  18838788
• Linkage between circadian clock and tricarboxylic acid cycle in Arabidopsis.   DOI:  10.1073/pnas.0900952106 ;  PMID:  19820331
• PSEUDO-RESPONSE REGULATORS 9, 7, and 5 are transcriptional repressors in the Arabidopsis circadian clock.   DOI:  10.1105/tpc.109.072892 ;  PMID:  20233950
• F-box proteins FKF1 and LKP2 act in concert with ZEITLUPE to control Arabidopsis clock progression.   DOI:  10.1105/tpc.109.072843 ;  PMID:  20354196
• TCP transcription factors link the regulation of genes encoding mitochondrial proteins with the circadian clock in Arabidopsis thaliana.   DOI:  10.1105/tpc.110.074518 ;  PMID:  21183706
• LIGHT-REGULATED WD1 and PSEUDO-RESPONSE REGULATOR9 form a positive feedback regulatory loop in the Arabidopsis circadian clock.   DOI:  10.1105/tpc.110.081661 ;  PMID:  21357491
• REVEILLE8 and PSEUDO-REPONSE REGULATOR5 form a negative feedback loop within the Arabidopsis circadian clock.   DOI:  10.1371/journal.pgen.1001350 ;  PMID:  21483796
• Autophosphorylation profiling of Arabidopsis protein kinases using the cell-free system.   DOI:  10.1016/j.phytochem.2011.02.029 ;  PMID:  21477822
• HSP90 functions in the circadian clock through stabilization of the client F-box protein ZEITLUPE.   DOI:  10.1073/pnas.1110406108 ;  PMID:  21949396
• Transcriptional repressor PRR5 directly regulates clock-output pathways.   DOI:  10.1073/pnas.1205156109 ;  PMID:  23027938
• Molecular mechanisms of circadian rhythm in Lotus japonicus and Arabidopsis thaliana are sufficiently compatible to regulate heterologous core clock genes robustly.   DOI:  10.1271/bbb.120538 ;  PMID:  23221703
• The unique function of the Arabidopsis circadian clock gene PRR5 in the regulation of shade avoidance response.   DOI:  10.4161/psb.23534 ;  PMID:  23333981
• A DEAD box RNA helicase is critical for pre-mRNA splicing, cold-responsive gene regulation, and cold tolerance in Arabidopsis.   DOI:  10.1105/tpc.112.108340 ;  PMID:  23371945
• LNK1 and LNK2 are transcriptional coactivators in the Arabidopsis circadian oscillator.   DOI:  10.1105/tpc.114.126573 ;  PMID:  25012192
• LNK1 and LNK2 recruitment to the evening element require morning expressed circadian related MYB-like transcription factors.   DOI:  10.1080/15592324.2015.1010888 ;  PMID:  25848708
• Defining the robust behaviour of the plant clock gene circuit with absolute RNA timeseries and open infrastructure.   DOI:  10.1098/rsob.150042 ;  PMID:  26468131
• A G-Box-Like Motif Is Necessary for Transcriptional Regulation by Circadian Pseudo-Response Regulators in Arabidopsis.   DOI:  10.1104/pp.15.01562 ;  PMID:  26586835
• Direct Repression of Evening Genes by CIRCADIAN CLOCK-ASSOCIATED1 in the Arabidopsis Circadian Clock.   DOI:  10.1105/tpc.15.00737 ;  PMID:  26941090
• LWD-TCP complex activates the morning gene CCA1 in Arabidopsis.   DOI:  10.1038/ncomms13181 ;  PMID:  27734958
• CORRECTION. A G-Box-Like Motif Is Necessary for Transcriptional Regulation by Circadian Pseudo-Response Regulators in Arabidopsis.   DOI:  10.1104/pp.16.00089 ;  PMID:  26826726
• and Low Temperature-Regulated COR27 and COR28 Play Roles in the Arabidopsis Circadian Clock.   DOI:  10.1105/tpc.16.00354 ;  PMID:  27837007
• COR27 and COR28 encode nighttime repressors integrating Arabidopsis circadian clock and cold response.   DOI:  10.1111/jipb.12512 ;  PMID:  27990760
• Circadian Waves of Transcriptional Repression Shape PIF-Regulated Photoperiod-Responsive Growth in Arabidopsis.   DOI:  10.1016/j.cub.2017.12.021 ;  PMID:  29337078
• The HAF2 protein shapes histone acetylation levels of PRR5 and LUX loci in Arabidopsis.   DOI:  10.1007/s00425-018-2921-y ;  PMID:  29789923
• PRR5, 7 and 9 positively modulate TOR signaling-mediated root cell proliferation by repressing TANDEM ZINC FINGER 1 in Arabidopsis.   DOI:  10.1093/nar/gkz191 ;  PMID:  30892623
• Luciferase-Based Screen for Post-translational Control Factors in the Regulation of the Pseudo-Response Regulator PRR7.   DOI:  10.3389/fpls.2019.00667 ;  PMID:  31191580
• 3,4-Dibromo-7-Azaindole Modulates Arabidopsis Circadian Clock by Inhibiting Casein Kinase 1 Activity.   DOI:  10.1093/pcp/pcz183 ;  PMID:  31529098
• TRANSPARENT TESTA GLABRA 1 participates in flowering time regulation in Arabidopsis thaliana.   DOI:  10.7717/peerj.8303 ;  PMID:  31998554
• Pseudo Response Regulators Regulate Photoperiodic Hypocotyl Growth by Repressing PIF4/5 Transcription.   DOI:  10.1104/pp.19.01599 ;  PMID:  32165445
• Co-expression Networks From Gene Expression Variability Between Genetically Identical Seedlings Can Reveal Novel Regulatory Relationships.   DOI:  10.3389/fpls.2020.599464 ;  PMID:  33384705
• The Arabidopsis circadian clock protein PRR5 interacts with and stimulates ABI5 to modulate abscisic acid signaling during seed germination.   DOI:  10.1093/plcell/koab168 ;  PMID:  34152411
• BBX19 fine-tunes the circadian rhythm by interacting with PSEUDO-RESPONSE REGULATOR proteins to facilitate their repressive effect on morning-phased clock genes.   DOI:  10.1093/plcell/koab133 ;  PMID:  34164694
• The 5'-3' mRNA Decay Pathway Modulates the Plant Circadian Network in Arabidopsis.   DOI:  10.1093/pcp/pcac126 ;  PMID:  36066193
• ZTL regulates thermomorphogenesis through TOC1 and PRR5.   DOI:  10.1111/pce.14542 ;  PMID:  36655421
• B-Box proteins BBX28 and BBX29 interplay with PSEUDO-RESPONSE REGULATORS to fine-tune circadian clock in Arabidopsis.   DOI:  10.1111/pce.14648 ;  PMID:  37312621
• Two-component signal transduction pathways in Arabidopsis.   DOI:  10.1104/pp.005504 ;  PMID:  12068096
• Circadian waves of expression of the APRR1/TOC1 family of pseudo-response regulators in Arabidopsis thaliana: insight into the plant circadian clock.   DOI:  10.1093/pcp/pcd043 ;  PMID:  11100772
• phyA dominates in transduction of red-light signals to rapidly responding genes at the initiation of Arabidopsis seedling de-etiolation.   DOI:  10.1111/j.1365-313X.2006.02914.x ;  PMID:  17076805

Sequences: