Gene Details:

• Gene ID: AT5G22750
• Gene Symbol: RAD5, RAD5A
• Gene Name:
• Description: DNA/RNA helicase protein;(source:Araport11)
• TAIR Accession:
• Genome: Araport11_genome_release
• Species: Arabidopsis thaliana

Transcripts:

• AT5G22750.1

Plant Ontology Annotations:

• PO:0000084  — plant sperm cell — célula espermática o esperma (Spanish, exact), male gamete (exact), microgamete (exact), 植物精子細胞 (Japanese, exact), sperm nucleus (related), sperm cell (broad)

Germplasm Phenotype:

• hrq1-1 rad5A-2  — Significant hypersensitivity against cisplatin and MMC.
• rad5A-2  — Strong sensitivity against both cisplatin and MMC.

Function-related keywords:

• plant sperm cell

Literature:

• Evaluation and classification of RING-finger domains encoded by the Arabidopsis genome.   DOI:  10.1186/gb-2002-3-4-research0016 ;  PMID:  11983057
• Components of nucleotide excision repair and DNA damage tolerance in Arabidopsis thaliana.   DOI:  10.1002/em.20094 ;  PMID:  15645454
• Genome-wide identification of potential plant E2F target genes.   DOI:  10.1104/pp.105.066290 ;  PMID:  16126853
• A transcriptome-based characterization of habituation in plant tissue culture.   DOI:  10.1104/pp.105.076059 ;  PMID:  16489130
• A homolog of ScRAD5 is involved in DNA repair and homologous recombination in Arabidopsis.   DOI:  10.1104/pp.108.116806 ;  PMID:  18310306
• RAD5A, RECQ4A, and MUS81 have specific functions in homologous recombination and define different pathways of DNA repair in Arabidopsis thaliana.   DOI:  10.1105/tpc.110.078568 ;  PMID:  20971895
• RAD5a and REV3 function in two alternative pathways of DNA-damage tolerance in Arabidopsis.   DOI:  10.1016/j.dnarep.2011.04.009 ;  PMID:  21549648
• The nuclease FAN1 is involved in DNA crosslink repair in Arabidopsis thaliana independently of the nuclease MUS81.   DOI:  10.1093/nar/gkv208 ;  PMID:  25779053
• The Translesion Polymerase ζ Has Roles Dependent on and Independent of the Nuclease MUS81 and the Helicase RECQ4A in DNA Damage Repair in Arabidopsis.   DOI:  10.1104/pp.15.00806 ;  PMID:  26474640
• The DNA translocase RAD5A acts independently of the other main DNA repair pathways, and requires both its ATPase and RING domain for activity in Arabidopsis thaliana.   DOI:  10.1111/tpj.13602 ;  PMID:  28509359
• The RecQ-like helicase HRQ1 is involved in DNA crosslink repair in Arabidopsis in a common pathway with the Fanconi anemia-associated nuclease FAN1 and the postreplicative repair ATPase RAD5A.   DOI:  10.1111/nph.15109 ;  PMID:  29577315
• Genetic analysis of DNA-damage tolerance pathways in Arabidopsis.   DOI:  10.1007/s00299-022-02942-2 ;  PMID:  36319861
• Repertoire of plant RING E3 ubiquitin ligases revisited: New groups counting gene families and single genes.   DOI:  10.1371/journal.pone.0203442 ;  PMID:  30169501

Sequences: