Gene Details:

• Gene ID: AT5G20930
• Gene Symbol: TSL
• Gene Name: TOUSLED
• Description: Protein kinase superfamily protein;(source:Araport11)
• TAIR Accession: locus:2147087
• Genome: Araport11_genome_release
• Species: Arabidopsis thaliana

Transcripts:

• AT5G20930.1

Plant Ontology Annotations:

• PO:0009005  — root — raíz (Spanish, exact), radices (exact, plural), radix (exact), 根 (Japanese, exact), aerial root (narrow), climbing root (narrow)
• PO:0000084  — plant sperm cell — célula espermática o esperma (Spanish, exact), male gamete (exact), microgamete (exact), 植物精子細胞 (Japanese, exact), sperm nucleus (related), sperm cell (broad)

Gene Ontology:

• GO:0005634  — located in — nucleus
• GO:0005634  — is active in — nucleus
• GO:0004674  — enables — protein serine/threonine kinase activity
• GO:0005515  — enables — protein binding
• GO:0018105  — involved in — peptidyl-serine phosphorylation
• GO:1900368  — acts upstream of or within — regulation of post-transcriptional gene silencing by regulatory ncRNA
• GO:0007059  — involved in — chromosome segregation
• GO:0005737  — located in — cytoplasm
• GO:0035556  — involved in — intracellular signal transduction
• GO:0042802  — enables — identical protein binding

Germplasm Phenotype:

• CS8168  — flowering delayed 1 week compared to wild type; slightly increased number of rosette leaves; deeply serrated leaves; secondary axes arise from axils of cauline leaves on main inflorescence - cauline leaves are rolled around the new axis; abnormal flowers with fewer, variable numbers of organs formed in all whorls (sepals, petals, anthers and gynoecium); no homeotic conversions among organ types occur; some floral organs are misshapen, reduced in size or filamentous; sterile at 22C, slightly fertile at 16C.
• CS8169  — flowering delayed 1 week compared to wild type; slightly increased number of rosette leaves; deeply serrated leaves; secondary axes arise from axils of cauline leaves on main inflorescence - cauline leaves are rolled around the new axis; abnormal flowers with fewer, variable organs formed in all whorls (sepals, petals, anthers and gynoecium); no homeotic conversions among organ types occur; some floral organs are misshapen, reduced in size or filamentous; sterile at 22C; slightly fertile at 16C.

Function-related keywords:

• root ,  plant sperm cell

Literature:

• TOUSLED participates in apical tissue formation during gynoecium development in Arabidopsis.   DOI:  10.1105/tpc.9.3.335 ;  PMID:  9090879
• TOUSLED kinase activity oscillates during the cell cycle and interacts with chromatin regulators.   DOI:  10.1104/pp.103.038117 ;  PMID:  15047893
• High-throughput protein localization in Arabidopsis using Agrobacterium-mediated transient expression of GFP-ORF fusions.   DOI:  10.1111/j.1365-313X.2004.02281.x ;  PMID:  15610358
• Evidence that CRABS CLAW and TOUSLED have conserved their roles in carpel development since the ancestor of the extant angiosperms.   DOI:  10.1073/pnas.0409577102 ;  PMID:  15767586
• The protein kinase TOUSLED is required for maintenance of transcriptional gene silencing in Arabidopsis.   DOI:  10.1038/sj.embor.7400852 ;  PMID:  17110953
• Global analysis of Arabidopsis gene expression uncovers a complex array of changes impacting pathogen response and cell cycle during geminivirus infection.   DOI:  10.1104/pp.108.121038 ;  PMID:  18650403
• Autophosphorylation profiling of Arabidopsis protein kinases using the cell-free system.   DOI:  10.1016/j.phytochem.2011.02.029 ;  PMID:  21477822
• The Arabidopsis thaliana chloroplast proteome reveals pathway abundance and novel protein functions.   DOI:  10.1016/j.cub.2004.02.039 ;  PMID:  15028209

Sequences: