Gene Details:
- Gene ID: AT5G17690
- Gene Symbol: AtLHP1, LHP1, TFL2
- Gene Name: LIKE HETEROCHROMATIN PROTEIN 1, TERMINAL FLOWER 2
- Description: like heterochromatin protein (LHP1);(source:Araport11)
- TAIR Accession: locus:2176006
- Genome: Araport11_genome_release
- Species: Arabidopsis thaliana
Transcripts:
Plant Ontology Annotations:
- PO:0009005 — root — raíz (Spanish, exact), radices (exact, plural), radix (exact), 根 (Japanese, exact), aerial root (narrow), climbing root (narrow)
Gene Ontology:
- GO:0035064 — enables — methylated histone binding
- GO:0009910 — acts upstream of or within — negative regulation of flower development
- GO:0045892 — involved in — negative regulation of DNA-templated transcription
- GO:0031507 — involved in — heterochromatin formation
- GO:0005515 — enables — protein binding
- GO:0010016 — acts upstream of or within — shoot system morphogenesis
- GO:0010048 — acts upstream of or within — vernalization response
- GO:0003682 — enables — chromatin binding
- GO:0005634 — located in — nucleus
- GO:0043565 — enables — sequence-specific DNA binding
- GO:0000792 — located in — heterochromatin
- GO:0009825 — acts upstream of or within — multidimensional cell growth
- GO:0003723 — enables — RNA binding
- GO:0009648 — acts upstream of or within — photoperiodism
- GO:0009507 — located in — chloroplast
- GO:0003677 — enables — DNA binding
- GO:0048573 — acts upstream of or within — photoperiodism, flowering
- GO:0042802 — enables — identical protein binding
- GO:0045814 — acts upstream of or within — negative regulation of gene expression, epigenetic
- GO:0006325 — acts upstream of or within — chromatin organization
- GO:0000791 — located in — euchromatin
- GO:0003935 — enables — GTP cyclohydrolase II activity
Germplasm Phenotype:
- CS3796 — early flowering; rosette leaves are smaller than wt or tfl1; reduced plant height (shortened internode length); premature termination of the main inflorescence with the formation of a terminal flower structure, causing the early release of numerous secondary inflorescences; terminal flowers commonly develop as separate flowers with pedicels and are occasionally sessile and fused with the last initiated lateral flower(s), frequently show mixed organ identity, such as carpeloid sepals and stamens, and sometimes chimeric organs are produced; severity and variation of floral defects is greater than in tfl1; reduced photoperiod sensitivity.
- CS3797 — early flowering; rosette leaves are smaller than wt or tfl1; reduced plant height (shortened internode length); premature termination of the main inflorescence with the formation of a terminal flower structure, causing the early release of many secondary inflorescences; terminal flowers commonly develop as separate flowers with pedicels and are occasionally sessile and fused with the last initiated lateral flower(s), frequently show mixed organ identity, such as carpeloid sepals and stamens, and sometimes chimeric organs are produced; severity and variation of floral defects is greater than in tfl1; reduced photoperiod sensitivity
- CS6397 — Morphology similar to tfl2-1 and tfl2-2; early flowering; rosette leaves are smaller than wt or tfl1; reduced plant height (shortened internode length); premature termination of the main inflorescence with the formation of a terminal flower structure, causing the early release of numerous secondary inflorescences; early senescence; altered glucosinolate profile in leaves, seeds and roots; increased sensitivity to clubroot disease (Plasmodiophora brassicae); thermosensitive; reduced Hsp90 expression; increased tryptophan content in seedlings, reduced tryptophan oxidizing enzyme in seedlings; altered auxin (indole acetic acid) metabolism.
- eol1-1/lhp1-3 — Small plants and early flowering.
- icu11-1 tlf2-2 — Strong reduction in body size, seedlings lacked rosette leaves, skipped vegetative growth, flowered upon germination, generating small, sterile flowers, involute cotyledons, aberrant floral tissues comprising a mixture of stamens, carpels, stigma and ovules.
- lhp1-1 — Callus formation is accelerated in experiments performed with lhp1-1 mutant seeds.
- lhp1-1 — The lhp1-1 mutant flowers early and displays aberrant organ development and plant architecture.
- lhp1-2 — The lhp1-2 mutant flowers early and displays aberrant organ development and plant architecture.
- ring1a/ring1b/tfl2-2 — Plants are extremely small with a reduced number of leaves, leaves are sessile and the inflorescences are completely arrested.Enhanced de-repression of KNOX gene expression.
Function-related keywords:
Literature:
- The TERMINAL FLOWER2 (TFL2) gene controls the reproductive transition and meristem identity in Arabidopsis thaliana. DOI: 10.1093/genetics/149.2.597 ; PMID: 9611176
- Arabidopsis TERMINAL FLOWER 2 gene encodes a heterochromatin protein 1 homolog and represses both FLOWERING LOCUS T to regulate flowering time and several floral homeotic genes. DOI: 10.1093/pcp/pcg091 ; PMID: 12826620
- Terminal flower2, an Arabidopsis homolog of heterochromatin protein1, counteracts the activation of flowering locus T by constans in the vascular tissues of leaves to regulate flowering time. DOI: 10.1105/tpc.016345 ; PMID: 14630968
- The Arabidopsis heterochromatin protein1 homolog (TERMINAL FLOWER2) silences genes within the euchromatic region but not genes positioned in heterochromatin. DOI: 10.1093/pcp/pci195 ; PMID: 16131496
- LHP1, the Arabidopsis homologue of HETEROCHROMATIN PROTEIN1, is required for epigenetic silencing of FLC. DOI: 10.1073/pnas.0507427103 ; PMID: 16549797
- DamID, a new tool for studying plant chromatin profiling in vivo, and its use to identify putative LHP1 target loci. DOI: 10.1111/j.1365-313X.2006.02859.x ; PMID: 16972870
- INCURVATA2 encodes the catalytic subunit of DNA Polymerase alpha and interacts with genes involved in chromatin-mediated cellular memory in Arabidopsis thaliana. DOI: 10.1105/tpc.107.054130 ; PMID: 17873092
- Vernalization-induced trimethylation of histone H3 lysine 27 at FLC is not maintained in mitotically quiescent cells. DOI: 10.1016/j.cub.2007.10.026 ; PMID: 17980595
- Arabidopsis TFL2/LHP1 specifically associates with genes marked by trimethylation of histone H3 lysine 27. DOI: 10.1371/journal.pgen.0030086 ; PMID: 17542647
- Global analysis of Arabidopsis gene expression uncovers a complex array of changes impacting pathogen response and cell cycle during geminivirus infection. DOI: 10.1104/pp.108.121038 ; PMID: 18650403
- Diversification of photoperiodic response patterns in a collection of early-flowering mutants of Arabidopsis. DOI: 10.1104/pp.108.127639 ; PMID: 18799658
- The role of auxins and cytokinins in the mutualistic interaction between Arabidopsis and Piriformospora indica. DOI: 10.1094/MPMI-21-10-1371 ; PMID: 18785832
- Polycomb silencing of KNOX genes confines shoot stem cell niches in Arabidopsis. DOI: 10.1016/j.cub.2008.11.019 ; PMID: 19097900
- Regulation of floral patterning by flowering time genes. DOI: 10.1016/j.devcel.2009.03.011 ; PMID: 19460347
- Defining the functional network of epigenetic regulators in Arabidopsis thaliana. DOI: 10.1093/mp/ssp017 ; PMID: 19825647
- EARLY IN SHORT DAYS 7 (ESD7) encodes the catalytic subunit of DNA polymerase epsilon and is required for flowering repression through a mechanism involving epigenetic gene silencing. DOI: 10.1111/j.1365-313X.2009.04093.x ; PMID: 19947980
- A role for CHROMOMETHYLASE3 in mediating transposon and euchromatin silencing during egg cell reprogramming in Arabidopsis. DOI: 10.4161/psb.5.10.11905 ; PMID: 20505370
- cis-Regulatory elements and chromatin state coordinately control temporal and spatial expression of FLOWERING LOCUS T in Arabidopsis. DOI: 10.1105/tpc.110.074682 ; PMID: 20472817
- Vernalization-mediated VIN3 Induction Overcomes the LIKE-HETEROCHROMATIN PROTEIN1/POLYCOMB REPRESSION COMPLEX2-mediated epigenetic repression. DOI: 10.1104/pp.110.161083 ; PMID: 20671111
- Mechanisms underlying vernalization-mediated VIN3 induction in Arabidopsis. DOI: 10.4161/psb.5.11.13465 ; PMID: 21051939
- The cyclophilin AtCYP71 interacts with CAF-1 and LHP1 and functions in multiple chromatin remodeling processes. DOI: 10.1093/mp/ssr036 ; PMID: 21596687
- Arabidopsis thaliana TERMINAL FLOWER2 is involved in light-controlled signalling during seedling photomorphogenesis. DOI: 10.1111/j.1365-3040.2011.02468.x ; PMID: 22145973
- The catalytic subunit of Arabidopsis DNA polymerase α ensures stable maintenance of histone modification. DOI: 10.1242/dev.084624 ; PMID: 23154417
- Starch metabolism and antiflorigenic signals modulate the juvenile-to-adult phase transition in Arabidopsis. DOI: 10.1111/pce.12088 ; PMID: 23452177
- Arabidopsis AL PHD-PRC1 complexes promote seed germination through H3K4me3-to-H3K27me3 chromatin state switch in repression of seed developmental genes. DOI: 10.1371/journal.pgen.1004091 ; PMID: 24465219
- The Arabidopsis GAGA-Binding Factor BASIC PENTACYSTEINE6 Recruits the POLYCOMB-REPRESSIVE COMPLEX1 Component LIKE HETEROCHROMATIN PROTEIN1 to GAGA DNA Motifs. DOI: 10.1104/pp.15.00409 ; PMID: 26025051
- A Domesticated Transposase Antagonises Silencing Mediated by Polycomb Group Proteins and Is an Accessory Component of Polycomb Repressive Complex 2. DOI: 10.1371/journal.pgen.1005660 ; PMID: 26642436
- Complementary Activities of TELOMERE REPEAT BINDING Proteins and Polycomb Group Complexes in Transcriptional Regulation of Target Genes. DOI: 10.1105/tpc.15.00787 ; PMID: 26721861
- Arabidopsis Flower and Embryo Developmental Genes are Repressed in Seedlings by Different Combinations of Polycomb Group Proteins in Association with Distinct Sets of Cis-regulatory Elements. DOI: 10.1371/journal.pgen.1005771 ; PMID: 26760036
- Transcription factors AS1 and AS2 interact with LHP1 to repress KNOX genes in Arabidopsis. DOI: 10.1111/jipb.12485 ; PMID: 27273574
- A cis cold memory element and a trans epigenome reader mediate Polycomb silencing of FLC by vernalization in Arabidopsis. DOI: 10.1038/ng.3712 ; PMID: 27819666
- The Arabidopsis Polycomb Repressive Complex 1 (PRC1) Components AtBMI1A, B, and C Impact Gene Networks throughout All Stages of Plant Development. DOI: 10.1104/pp.16.01259 ; PMID: 27837089
- Correction: Arabidopsis Flower and Embryo Developmental Genes are Repressed in Seedlings by Different Combinations of Polycomb Group Proteins in Association with Distinct Sets of Cis-regulatory Elements. DOI: 10.1371/journal.pgen.1006574 ; PMID: 28122004
- H2A monoubiquitination in Arabidopsis thaliana is generally independent of LHP1 and PRC2 activity. DOI: 10.1186/s13059-017-1197-z ; PMID: 28403905
- Ctf4-related protein recruits LHP1-PRC2 to maintain H3K27me3 levels in dividing cells in Arabidopsis thaliana. DOI: 10.1073/pnas.1620955114 ; PMID: 28428341
- Arabidopsis PWWP domain proteins mediate H3K27 trimethylation on FLC and regulate flowering time. DOI: 10.1111/jipb.12630 ; PMID: 29314758
- A chromatin loop represses WUSCHEL expression in Arabidopsis. DOI: 10.1111/tpj.13921 ; PMID: 29660180
- LHP1 Interacts with ATRX through Plant-Specific Domains at Specific Loci Targeted by PRC2. DOI: 10.1016/j.molp.2018.05.004 ; PMID: 29793052
- INCURVATA11 and CUPULIFORMIS2 Are Redundant Genes That Encode Epigenetic Machinery Components in Arabidopsis. DOI: 10.1105/tpc.18.00300 ; PMID: 29915151
- Plant HP1 protein ADCP1 links multivalent H3K9 methylation readout to heterochromatin formation. DOI: 10.1038/s41422-018-0104-9 ; PMID: 30425322
- Arabidopsis PEAPODs function with LIKE HETEROCHROMATIN PROTEIN1 to regulate lateral organ growth. DOI: 10.1111/jipb.12841 ; PMID: 31099089
- The B3-Domain Transcription Factor VAL1 Regulates the Floral Transition by Repressing FLOWERING LOCUS T. DOI: 10.1104/pp.19.00642 ; PMID: 31289216
- The Polycomb protein LHP1 regulates Arabidopsis thaliana stress responses through the repression of the MYC2-dependent branch of immunity. DOI: 10.1111/tpj.14502 ; PMID: 31437321
- BPC transcription factors and a Polycomb Group protein confine the expression of the ovule identity gene SEEDSTICK in Arabidopsis. DOI: 10.1111/tpj.14673 ; PMID: 31909505
- HSI2/VAL1 and HSL1/VAL2 function redundantly to repress DOG1 expression in Arabidopsis seeds and seedlings. DOI: 10.1111/nph.16559 ; PMID: 32201955
- Nuclear import of LIKE HETEROCHROMATIN PROTEIN1 is redundantly mediated by importins α-1, α-2 and α-3. DOI: 10.1111/tpj.14796 ; PMID: 32365248
- The Arabidopsis epigenetic regulator ICU11 as an accessory protein of Polycomb Repressive Complex 2. DOI: 10.1073/pnas.1920621117 ; PMID: 32601198
- Loss of Polycomb proteins CLF and LHP1 leads to excessive RNA degradation in Arabidopsis. DOI: 10.1093/jxb/erac216 ; PMID: 35595271
- The Arabidopsis APOLO and human UPAT sequence-unrelated long noncoding RNAs can modulate DNA and histone methylation machineries in plants. DOI: 10.1186/s13059-022-02750-7 ; PMID: 36038910
- TOR represses stress responses through global regulation of H3K27 trimethylation in plants. DOI: 10.1093/jxb/erac486 ; PMID: 36515098
- Responsiveness to long days for flowering is reduced in Arabidopsis by yearly variation in growing season temperatures. DOI: 10.1111/pce.14632 ; PMID: 37249162
- Arabidopsis TFL2/LHP1 specifically associates with genes marked by trimethylation of histone H3 lysine 27. DOI: 10.1371/journal.pgen.0030086 ; PMID: 17542647
- Diversification of photoperiodic response patterns in a collection of early-flowering mutants of Arabidopsis. DOI: 10.1104/pp.108.127639 ; PMID: 18799658
Sequences:
cDNA Sequence
- >AT5G17690.1
AAAGAGAATCCAAAAAAGTGAAAAAACTGGTCTTTGAGGTCAGGTCAGGTCTTCTTCCTGCAAAAACAAAAACCTCAGAAATAGAGAAAAAGTTTCAATCTTTCTTCATCTTCTTCCTCCAAAATCCTTGATTTCTAAAAAGGAGAAGAAGAGAAGAGAACGCGATTACCTTGATTCACCCTCCTCCTTCAGGTTTGGGAGGCTCGAATACTCAGGAAATGAAAGGGGCAAGTGGTGCTGTTAAGAAGAAACCCCAGGTGTTGAACGAAGCTGGTGAGGCGGAGACGGCGGTGGAAACAGTCGGAGAAAGCCGGAAAATTAGTGGAGACGGTGGGTTTGGCAGTGACGACGGCGGAGGGGGAGGTGGAGGTGGAAGTGGAGAGTCGATTCTTCGCGAGATTGGTGATGATAGGCCTACGGAGGATGGAGATGAAGAAGAAGAAGAGGACGAGGATGAAGATGATGGAGGTGATGAGGAAGATGAAGAAGGAGAAGGAGAAGGTGGGCAAGAGGAAAGGCCAAAGCTTGATGAAGGGTTTTATGAAATTGAAGCTATTCGTCGTAAGAGAGTTCGAAAAGGCAAGGTTCAGTATCTAATTAAATGGCGCGGATGGCCTGAAACTGCCAACACATGGGAGCCTTTAGAGAATCTCCAGTCTATTGCTGATGTTATAGATGCCTTTGAGGGAAGTTTGAAGCCAGGAAAGCCTGGTAGGAAACGGAAGCGCAAATATGCAGGTCCTCATTCTCAGATGAAGAAGAAGCAACGTTTAACATCTACATCACATGATGCTACTGAGAAATCTGACTCTTCTACGTCTCTCAACAACTCTAGCCTTCCTGACATTCCTGATCCACTAGACCTAAGCGGTTCGAGTCTATTAAATAGAGATGTGGAAGCGAAGAATGCTTATGTATCCAACCAAGTTGAAGCCAACAGTGGGAGTGTTGGGATGGCCCGACAAGTTCGTTTGATTGACAATGAGAAAGAATATGATCCAACACTTAACGAGCTACGAGGACCAGTCAACAATAGTAACGGTGCAGGATGTTCTCAAGGAGGAGGCATTGGTTCTGAAGGTGATAATGTAAGACCCAATGGCCTTCTCAAGGTTTATCCTAAGGAGCTTGATAAGAACAGTCGTTTCATAGGTGCTAAGCGGAGGAAGTCTGGTTCTGTGAAAAGATTCAAACAAGATGGATCCACAAGTAACAACCACACAGCACCTACAGATCAGAATCTGACACCAGATTTGACTACATTAGACTCTTTTGGTAGGATTGCAAGGATGGGGAATGAATATCCTGGTGTGATGGAAAATTGTAATTTGTCTCAGAAAACCAAGATTGAGGAGTTGGACATCACGAAGATACTTAAACCAATGAGTTTTACAGCATCTGTATCAGACAATGTCCAGGAAGTGTTGGTGACCTTTTTAGCGCTGAGGTCTGATGGGAAGGAAGCATTGGTGGACAACAGATTTCTCAAGGCTCACAATCCTCATCTCCTGATTGAATTCTATGAGCAACATCTCAAGTACAATCGAACGCCTTAAATCATCCGGAATGGTAAGAATTTGTTTGTACACAGCCCTTGTAGGTAGAAAAGATTAGATGGCTTCTTTATTCTAGCAGTGCAACATGTAGAGTCGAGGTAGCGACAATTGGATTTTGTATCGCGTCTCCGGGAGGTTTCAGATTGTAATTTATCTCCTCGGGTTCGTTGTGTTCACTCTCTATCTCTATCATAGTAAATCTTGTTACTTGGACCTTTGCTTCTTATAGCGGAAGTTTTCTTGTACTTGCTTCTTCAAAGATCAAGTTCATGATATGTTGATGTTATCAAAATATATGTGATCAATCAATATATAATAATTATGTTTACAAGCAAACCAAGTAATTTTTTTTACTTTCGTAT - >AT5G17690.2
AAAGAGAATCCAAAAAAGTGAAAAAACTGGTCTTTGAGGTCAGGTCAGGTCTTCTTCCTGCAAAAACAAAAACCTCAGAAATAGAGAAAAAGTTTCAATCTTTCTTCATCTTCTTCCTCCAAAATCCTTGATTTCTAAAAAGGAGAAGAAGAGAAGAGAACGCGATTACCTTGATTCACCCTCCTCCTTCAGGTTTGGGAGGCTCGAATACTCAGGAAATGAAAGGGGCAAGTGGTGCTGTTAAGAAGAAACCCCAGGTGTTGAACGAAGCTGGTGAGGCGGAGACGGCGGTGGAAACAGTCGGAGAAAGCCGGAAAATTAGTGGAGACGGTGGGTTTGGCAGTGACGACGGCGGAGGGGGAGGTGGAGGTGGAAGTGGAGAGTCGATTCTTCGCGAGATTGGTGATGATAGGCCTACGGAGGATGGAGATGAAGAAGAAGAAGAGGACGAGGATGAAGATGATGGAGGTGATGAGGAAGATGAAGAAGGAGAAGGAGAAGGTGGGCAAGAGGAAAGGCCAAAGCTTGATGAAGGGTTTTATGAAATTGAAGCTATTCGTCGTAAGAGAGTTCGAAAAGGCAAGGTTCAGTATCTAATTAAATGGCGCGGATGGCCTGAAACTGCCAACACATGGGAGCCTTTAGAGAATCTCCAGTCTATTGCTGATGTTATAGATGCCTTTGAGGGAAGTTTGAAGCCAGGAAAGCCTGGTAGGAAACGGAAGCGCAAATATGCAGGTCCTCATTCTCAGATGAAGAAGAAGCAACGTTTAACATCTACATCACATGATGCTACTGAGAAATCTGACTCTTCTACGTCTCTCAACAACTCTAGCCTTCCTGACATTCCTGATCCACTAGACCTAAGCGGTTCGAGTCTATTAAATAGAGATGTGGAAGCGAAGAATGCTTATGTATCCAACCAAGTTGAAGCCAACAGTGGGAGTGTTGGGATGGCCCGACAAGTTCGTTTGATTGACAATGAGAAAGAATATGATCCAACACTTAACGAGCTACGAGGACCAGTCAACAATAGTAACGGTGCAGGATGTTCTCAAGGAGGAGGCATTGGTTCTGAAGGTGATAATGTAAGACCCAATGGCCTTCTCAAGGTTTATCCTAAGGAGCTTGATAAGAACAGTCGTTTCATAGGTGCTAAGCGGAGGAAGTCTGGTTCTGTGAAAAGATTCAAACAAGATGGATCCACAAGTAACAACCACACAGCACCTACAGATCAGAATCTGACACCAGATTTGACTACATTAGACTCTTTTGGTAGGATTGCAAGGATGGGGAATGAATATCCTGGTGTGATGGAAAATTGTAATTTGTCTCAGAAAACCAAGATTGAGGAGTTGGACATCACGAAGATACTTAAACCAATGAGTTTTACAGCATCTGTATCAGACAATGTCCAGGAAGTGTTGGTGACCTTTTTAGCGCTGAGGTCTGATGGGAAGGAAGCATTGGTGGACAACAGATTTCTCAAGGCTCACAATCCTCATCTCCTGATTGAATTCTATGAGCAACATCTCAAGTACAATCGAACGCCTTAAATCATCCGGAATGGTAAGAATTTGTTTGTACACAGCCCTTGTAGGTAGAAAAGATTAGATGGCTTCTTTATTCTAGCAGTGCAACATGTAGAGTCGAGGTAGCGACAATTGGATTTTGTATCGCGTCTCCGGGAGGTTTCAGATTGTAATTTATCTCCTCGGGTTCGTTGTGTTCACTCTCTATCTCTATCATAGTAAATCTTGTTACTTGGACCTTTGCTTCTTATAGCGGAAGTTTTCTTGTACTTGCTTCTTCAAAGATCAAGTTCATGATATGTTGATGTTATCAAAATATATGTGATCAATCAATATATAATAATTATGTTTACAAGCAAACCAAGTAATTTTTTTTACTTTCGTAT - >AT5G17690.3
AAAGAGAATCCAAAAAAGTGAAAAAACTGGTCTTTGAGGTCAGGTCAGGTCTTCTTCCTGCAAAAACAAAAACCTCAGAAATAGAGAAAAAGTTTCAATCTTTCTTCATCTTCTTCCTCCAAAATCCTTGATTTCTAAAAAGGAGAAGAAGAGAAGAGAACGCGATTACCTTGATTCACCCTCCTCCTTCAGGTTTGGGAGGCTCGAATACTCAGGAAATGAAAGGGGCAAGTGGTGCTGTTAAGAAGAAACCCCAGGTGTTGAACGAAGCTGGTGAGGCGGAGACGGCGGTGGAAACAGTCGGAGAAAGCCGGAAAATTAGTGGAGACGGTGGGTTTGGCAGTGACGACGGCGGAGGGGGAGGTGGAGGTGGAAGTGGAGAGTCGATTCTTCGCGAGATTGGTGATGATAGGCCTACGGAGGATGGAGATGAAGAAGAAGAAGAGGACGAGGATGAAGATGATGGAGGTGATGAGGAAGATGAAGAAGGAGAAGGAGAAGGTGGGCAAGAGGAAAGGCCAAAGCTTGATGAAGGGTTTTATGAAATTGAAGCTATTCGTCGTAAGAGAGTTCGAAAAGGCAAGGTTCAGTATCTAATTAAATGGCGCGGATGGCCTGAAACTGCCAACACATGGGAGCCTTTAGAGAATCTCCAGTCTATTGCTGATGTTATAGATGCCTTTGAGGGAAGTTTGAAGCCAGGAAAGCCTGGTAGGAAACGGAAGCGCAAATATGCAGGTCCTCATTCTCAGATGAAGAAGAAGCAACGTTTAACATCTACATCACATGATGCTACTGAGAAATCTGACTCTTCTACGTCTCTCAACAACTCTAGCCTTCCTGACATTCCTGATCCACTAGACCTAAGCGGTTCGAGTCTATTAAATAGAGATGTGGAAGCGAAGAATGCTTATGTATCCAACCAAGTTGAAGCCAACAGTGGGAGTGTTGGGATGGCCCGACAAGTTCGTTTGATTGACAATGAGAAAGAATATGATCCAACACTTAACGAGCTACGAGGACCAGTCAACAATAGTAACGGTGCAGGATGTTCTCAAGGAGGAGGCATTGGTTCTGAAGGTGATAATGTAAGACCCAATGGCCTTCTCAAGGTTTATCCTAAGGAGCTTGATAAGAACAGTCGTTTCATAGGTGCTAAGCGGAGGAAGTCTGGTTCTGTGAAAAGATTCAAACAAGATGGATCCACAAGTAACAACCACACAGCACCTACAGATCAGAATCTGACACCAGATTTGACTACATTAGACTCTTTTGGTAGGATTGCAAGGATGGGGAATGAATATCCTGGTGTGATGGAAAATTGTAATTTGTCTCAGAAAACCAAGATTGAGGAGTTGGACATCACGAAGATACTTAAACCAATGAGTTTTACAGCATCTGTATCAGACAATGTCCAGGAAGTGTTGGTGACCTTTTTAGCGCTGAGGTCTGATGGGAAGGAAGCATTGGTGGACAACAGATTTCTCAAGGCTCACAATCCTCATCTCCTGATTGAATTCTATGAGCAACATCTCAAGTACAATCGAACGCCTTAAATCATCCGGAATGGTAAGAATTTGTTTGTACACAGCCCTTGTAGGTAGAAAAGATTAGATGGCTTCTTTATTCTAGCAGTGCAACATGTAGAGTCGAGGTAGCGACAATTGGATTTTGTATCGCGTCTCCGGGAGGTTTCAGATTGTAATTTATCTCCTCGGGTTCGTTGTGTTCACTCTCTATCTCTATCATAGTAAATCTTGTTACTTGGACCTTTGCTTCTTATAGCGGAAGTTTTCTTGTACTTGCTTCTTCAAAGATCAAGTTCATGATATGTTGATGTTATCAAAATATATGTGATCAATCAATATATAATAATTATGTTTACAAGCAAACCAAGTAATTTTTTTTACTTTCGTAT
CDS Sequence
Protein Sequence